Comparison · NCT01446965-7f5a413c
Wearable Defibrillator vs Conventional Treatment: Sudden Death Mortality
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Wearable Defibrillator vs Conventional Treatment: Sudden Death Mortality. Trial comparisons, record NCT01446965-7f5a413c. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01446965-7f5a413c
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0164 | 0.0111 | 0.0241 | wilson | |
| Risk in group 2 | 0.0244 | 0.0157 | 0.0378 | wilson | |
| Risk difference, group 1 minus group 2 | -0.00802 | -0.0224 | 0.00363 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.672 | 0.372 | 1.21 | log | |
| Odds ratio, group 1 over group 2 | 0.666 | 0.365 | 1.22 | log | |
| Number needed to treat, for one fewer participant with the outcome on Wearable Defibrillator than on Conventional Treatment | 125 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Wearable Defibrillator | subjects in the Device Group will receive a LifeVest® wearable cardioverter-defibrillator (manufacturer: ZOLL Medical Corporation) plus guideline-directed medical therapy for post-myocardial infarction patients~wearable defibrillator: LifeVest wearable defibrillator | 25 | 1,524 | OG000 |
| Group 2 | Conventional Treatment | subjects in the Control Group will only receive guideline-directed medical therapy for post-myocardial infarction patients | 19 | 778 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Sudden Death Mortality
- Description
For witnessed deaths, sudden cardiac death will be defined as an unexpected non-traumatic, non-self-inflicted fatality in otherwise stable participants who die within one hour of the onset of the terminal symptoms. For unwitnessed deaths, participants will meet the definition of sudden death if they are found dead within 24 hours of being well, assuming there is no evidence of another cause of death during that time period.
- Time frame
- three months after myocardial infarction
- Population
- A total of 2302 participants were included in the analyses.
Source ClinicalTrials.gov
Trial
- Title
- Vest Prevention of Early Sudden Death Trial and VEST Registry
- NCT number
- NCT01446965
- Phases
- NA
- Conditions
- Myocardial Infarction, Ventricular Dysfunction, Sudden Death, Ventricular Tachycardia, Ventricular Fibrillation
- Interventions
- wearable defibrillator
- Lead sponsor
- University of California, San Francisco
- Results first posted
- 2021-01-20
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01446965?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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