Comparison · NCT01446965-sae
Wearable Defibrillator vs Conventional Treatment: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Wearable Defibrillator vs Conventional Treatment: serious adverse events. Trial comparisons, record NCT01446965-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01446965-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.312 | 0.289 | 0.335 | wilson | |
| Risk in group 2 | 0.325 | 0.293 | 0.359 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0135 | -0.0542 | 0.0263 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.958 | 0.845 | 1.09 | log | |
| Odds ratio, group 1 over group 2 | 0.94 | 0.781 | 1.13 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on Wearable Defibrillator than on Conventional Treatment | 74 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Wearable Defibrillator | subjects in the Device Group will receive a LifeVest® wearable cardioverter-defibrillator (manufacturer: ZOLL Medical Corporation) plus guideline-directed medical therapy for post-myocardial infarction patients~wearable defibrillator: LifeVest wearable defibrillator | 475 | 1,524 | EG000 |
| Group 2 | Conventional Treatment | subjects in the Control Group will only receive guideline-directed medical therapy for post-myocardial infarction patients | 253 | 778 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- 3 months
Source ClinicalTrials.gov
Trial
- Title
- Vest Prevention of Early Sudden Death Trial and VEST Registry
- NCT number
- NCT01446965
- Phases
- NA
- Conditions
- Myocardial Infarction, Ventricular Dysfunction, Sudden Death, Ventricular Tachycardia, Ventricular Fibrillation
- Interventions
- wearable defibrillator
- Lead sponsor
- University of California, San Francisco
- Results first posted
- 2021-01-20
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01446965?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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