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Comparison · NCT01783860-sae

Doxycycline vs Oral Azithromycin: serious adverse events

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Doxycycline vs Oral Azithromycin: serious adverse events. Trial comparisons, record NCT01783860-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01783860-sae

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.240.1430.374wilson
Risk in group 20.060.02060.162wilson
Risk difference, group 1 minus group 20.180.03910.32newcombe hybrid score
Risk ratio, group 1 over group 241.213.3log
Odds ratio, group 1 over group 24.951.318.8log
Number needed to harm, for one more participant with a serious adverse event on Doxycycline than on Oral Azithromycin5.563.1325.6from the risk difference interval

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1DoxycyclineOral doxycycline 100mg capsule every 12 hours for one month~Doxycycline :1250EG000
Group 2Oral AzithromycinTwo 250 mg capsules (500 mg) of Azithromycin for the first day and 250mg/day for the next 4 days.~Azithromycin :350EG001

Harm

What it counts
Total, serious adverse events
Time frame

Source ClinicalTrials.gov

Trial

Title
Oral Azithromycin Versus Doxycycline in Posterior Blepharitis
NCT number
NCT01783860
Phases
PHASE2
Conditions
Posterior Blepharitis
Interventions
Azithromycin, Doxycycline
Lead sponsor
Tehran University of Medical Sciences
Results first posted
2014-02-12

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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