Comparison · NCT01876212-deaths
Vaccine (Cycle 1, Day 1) + Dasatinib (Cycle 2, D1) vs Vaccine + Dasatinib (Cycle 1, D1): deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Vaccine (Cycle 1, Day 1) + Dasatinib (Cycle 2, D1) vs Vaccine + Dasatinib (Cycle 1, D1): deaths from any cause. Trial comparisons, record NCT01876212-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT01876212-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.889 | 0.565 | 0.98 | wilson | |
| Risk in group 2 | 0.833 | 0.436 | 0.97 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0556 | -0.296 | 0.463 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.07 | 0.697 | 1.63 | log | |
| Odds ratio, group 1 over group 2 | 1.6 | 0.0806 | 31.8 | log | |
| Number needed to harm, for one more death from any cause on Vaccine (Cycle 1, Day 1) + Dasatinib (Cycle 2, D1) than on Vaccine + Dasatinib (Cycle 1, D1) | 18 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Vaccine (Cycle 1, Day 1) + Dasatinib (Cycle 2, D1) | Patients received vaccine on treatment Cycle 1, Day 1, and dasatinib beginning on treatment Cycle 2, Day 1 (week 5).~All patients received dasatinib at a starting oral dose of 70 mg twice daily, and dasatinib as (1) 50 mg and (1) 20 mg tablets twice daily (each 12 hours).~The DC vaccine was administered by a single intradermal injection of approximately 10\^7 cells (in the vicinity of the four nodal drainage groups of the four extremities) , on days 1 and 15 of each cycle. | 8 | 9 | EG000 |
| Group 2 | Vaccine + Dasatinib (Cycle 1, D1) | Patients received both vaccine and dasatinib beginning on treatment Cycle 1, Day 1.~All patients received dasatinib at a starting oral dose of 70 mg twice daily, and dasatinib as (1) 50 mg and (1) 20 mg tablets twice daily (each 12 hours).~The DC vaccine was administered by a single intradermal injection of approximately 10\^7 cells (in the vicinity of the four nodal drainage groups of the four extremities) , on days 1 and 15 of each cycle. | 5 | 6 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- Up to 3 years
Source ClinicalTrials.gov
Trial
- Title
- Dendritic Cell Vaccines + Dasatinib for Metastatic Melanoma
- NCT number
- NCT01876212
- Phases
- PHASE2
- Conditions
- Metastatic Melanoma
- Interventions
- DC vaccine, Dasatinib
- Lead sponsor
- Walter J. Storkus
- Results first posted
- 2019-08-06
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT01876212?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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