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Comparison · NCT02175225-deaths

Deferoxamine Mesylate vs Normal Saline: deaths from any cause

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Deferoxamine Mesylate vs Normal Saline: deaths from any cause. Trial comparisons, record NCT02175225-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02175225-deaths

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.08330.04830.14wilson
Risk in group 20.08160.04730.137wilson
Risk difference, group 1 minus group 20.0017-0.0640.068newcombe hybrid score
Risk ratio, group 1 over group 21.020.4742.2log
Odds ratio, group 1 over group 21.020.4442.36log
Number needed to harm, for one more death from any cause on Deferoxamine Mesylate than on Normal Saline588from the risk difference intervalthe interval includes no difference

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Deferoxamine MesylateDeferoxamine Mesylate (32 mg/kg/day) given by an intravenous infusion for 3 consecutive days~Deferoxamine Mesylate12144EG000
Group 2Normal SalineNormal saline (0.9% sodium chloride) given by intravenous infusion for 3 consecutive days~Placebo (for Deferoxamine Mesylate)12147EG001

Harm

What it counts
Total, all-cause mortality
Time frame
All-cause mortality was collected until 180 days post-randomization. Serious adverse events were collected until 90 days post-randomization. Non-serious adverse events were collected until day 7 post-randomization or hospital discharge, whichever is earlier.

Source ClinicalTrials.gov

Trial

Title
Intracerebral Hemorrhage Deferoxamine Trial - iDEF Ttrial
NCT number
NCT02175225
Phases
PHASE2
Conditions
Intracerebral Hemorrhage
Interventions
Deferoxamine Mesylate, Placebo (for Deferoxamine Mesylate)
Lead sponsor
Beth Israel Deaconess Medical Center
Results first posted
2019-05-30

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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