Comparison · NCT02240667-deaths
Dabigatran (Dabigatran vs VKA) vs Vitamin K Antagonists (VKA): deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Dabigatran (Dabigatran vs VKA) vs Vitamin K Antagonists (VKA): deaths from any cause. Trial comparisons, record NCT02240667-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02240667-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.013 | 0.00706 | 0.0237 | wilson | |
| Risk in group 2 | 0.00769 | 0.00329 | 0.0179 | wilson | |
| Risk difference, group 1 minus group 2 | 0.00528 | -0.0065 | 0.0169 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.69 | 0.579 | 4.91 | log | |
| Odds ratio, group 1 over group 2 | 1.7 | 0.576 | 4.98 | log | |
| Number needed to harm, for one more death from any cause on Dabigatran (Dabigatran vs VKA) than on Vitamin K Antagonists (VKA) | 189 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Dabigatran (Dabigatran vs VKA) | Patients with non-valvular AF treated with Dabigatran as the first Oral Anticoagulants (OACs) for stroke prevention. | 10 | 771 | EG000 |
| Group 2 | Vitamin K Antagonists (VKA) | Patients with non-valvular AF treated with VKA as the first Oral Anticoagulants (OACs) for stroke prevention. | 5 | 650 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- From start of treatment until six days after permanent treatment discontinuation or end of study, up to 12 months.
Source ClinicalTrials.gov
Trial
- Title
- Drug Persistence/Adherence in Patients Treated With Dabigatran or VKA for Stroke Prevention in Non Valvular Atrial Fibrillation (SPAF)
- NCT number
- NCT02240667
- Phases
- Conditions
- Atrial Fibrillation
- Interventions
- Dabigatran etexilate, Vitamin K antagonists
- Lead sponsor
- Boehringer Ingelheim
- Results first posted
- 2019-04-19
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02240667?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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