Comparison · NCT02507505-6c2d3f95
Regional Anesthesia vs General Anesthesia: Major Inpatient Morbidity
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Regional Anesthesia vs General Anesthesia: Major Inpatient Morbidity. Trial comparisons, record NCT02507505-6c2d3f95. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02507505-6c2d3f95
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.123 | 0.102 | 0.148 | wilson | |
| Risk in group 2 | 0.149 | 0.126 | 0.175 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0258 | -0.0595 | 0.00789 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.827 | 0.645 | 1.06 | log | |
| Odds ratio, group 1 over group 2 | 0.803 | 0.602 | 1.07 | log | |
| Number needed to treat, for one fewer participant with the outcome on Regional Anesthesia than on General Anesthesia | 38.8 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Regional Anesthesia | Approximately half of the subjects will be randomized to the arm which receives Regional Anesthesia.~Regional Anesthesia: Regional anesthesia involves temporarily numbing parts of the body with nerve blocks. Spinal anesthesia is a type of regional anesthesia that uses medications injected into the fluid surrounding the spinal cord to temporarily numb the legs and lower abdomen. Spinal anesthesia is the most widely used type of regional anesthesia for hip fracture surgery. While intravenous sedation is typically used for comfort with spinal anesthesia, invasive airway interventions are not typically required. | 98 | 795 | OG000 |
| Group 2 | General Anesthesia | Approximately half of the subjects will be randomized to the arm which receives General Anesthesia.~General Anesthesia: General anesthesia uses injected or inhaled medications to keep people unconscious during surgery. Since general anesthesia depresses breathing and impairs protective airway reflexes, invasive airway interventions such as breathing tube placement and mechanical ventilation are usually required. | 120 | 805 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Major Inpatient Morbidity
- Description
Indicates occurrence of any of 12 complications based on medical record review: Myocardial infarction; Nonfatal cardiac arrest; Stroke; Pneumonia; Pulmonary edema; Pulmonary embolism; Unplanned postoperative intubation; Surgical-site infection; Urinary tract infection; Any return to the operating room; Critical care admission; Acute kidney injury.
- Time frame
- During initial hospitalization until day of discharge or 30 days after randomization, whichever occurs first
- Population
Source ClinicalTrials.gov
Trial
- Title
- Regional Versus General Anesthesia for Promoting Independence After Hip Fracture
- NCT number
- NCT02507505
- Phases
- NA
- Conditions
- Hip Fractures
- Interventions
- Regional Anesthesia, General Anesthesia
- Lead sponsor
- University of Pennsylvania
- Results first posted
- 2024-05-13
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02507505?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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