Comparison · NCT02919683-sae
Nivolumab With Ipilimumab vs Nivolumab: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Nivolumab With Ipilimumab vs Nivolumab: serious adverse events. Trial comparisons, record NCT02919683-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02919683-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.133 | 0.0374 | 0.379 | wilson | |
| Risk in group 2 | 0.2 | 0.0705 | 0.452 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0667 | -0.336 | 0.211 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.667 | 0.129 | 3.44 | log | |
| Odds ratio, group 1 over group 2 | 0.615 | 0.0872 | 4.34 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on Nivolumab With Ipilimumab than on Nivolumab | 15 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Nivolumab With Ipilimumab | * Nivolumab to be delivered at a pre-determine dose for two weeks~* Ipilimumab to be delivered at a pre-determine dose for one week~* Blood Sample Collected~* Standard of Care Surgery~Nivolumab~Ipilimumab~Standard of Care Surgery | 2 | 15 | EG000 |
| Group 2 | Nivolumab | * Nivolumab to be delivered at a pre-determine dose for two weeks~* Blood Sample Collected~* Standard of Care Surgery~Nivolumab~Standard of Care Surgery | 3 | 15 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- All adverse events experienced by participants were collected from the time of the first dose of study treatment, through the study and until the final study visit 1 year after enrollment.
Source ClinicalTrials.gov
Trial
- Title
- Window Study of Nivolumab With or Without Ipilimumab in Squamous Cell Carcinoma of the Oral Cavity
- NCT number
- NCT02919683
- Phases
- PHASE2
- Conditions
- Head and Neck Cancer
- Interventions
- Nivolumab, Ipilimumab, Standard of Care Surgery
- Lead sponsor
- Dana-Farber Cancer Institute
- Results first posted
- 2020-07-31
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02919683?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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