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Comparison · NCT03509350-eb17f150

Treatment Protocol vs Control Protocol: Number of Participants Employed

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Treatment Protocol vs Control Protocol: Number of Participants Employed. Trial comparisons, record NCT03509350-eb17f150. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03509350-eb17f150

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.1720.110.258wilson
Risk in group 20.260.1830.356wilson
Risk difference, group 1 minus group 2-0.0887-0.2030.0271newcombe hybrid score
Risk ratio, group 1 over group 20.6590.3811.14log
Odds ratio, group 1 over group 20.5890.2941.18log
Number needed to treat, for one fewer participant with the outcome on Treatment Protocol than on Control Protocol11.3from the risk difference intervalthe interval includes no difference

Groups2

Group 2 names the comparator: control.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Treatment ProtocolParticipants randomized to the treatment protocol received the VICTAS Intervention, consisting of intravenous vitamin C, thiamine, and hydrocortisone for four days or until ICU discharge.1799OG000
Group 2Control ProtocolParticipants in the control group received a placebo to match the VICTAS intervention, which was administered for four days or until ICU discharge.2596OG001

Outcome

Type
SECONDARY
Title
Number of Participants Employed
Description
The Employment Questionnaire is a brief measure of the participant's employment history and ability or capacity to work. The number of participants who indicated being employed are presented here.
Time frame
Day 180
Population
This analysis includes participants who completed the Employment Questionnaire.

Source ClinicalTrials.gov

Trial

Title
Vitamin C, Thiamine, and Steroids in Sepsis
NCT number
NCT03509350
Phases
PHASE3
Conditions
Sepsis
Interventions
Vitamin C, Thiamine, Hydrocortisone, Vitamin C Placebo, Thiamine Placebo, Hydrocortisone Placebo
Lead sponsor
Emory University
Results first posted
2020-09-18

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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