Comparison · NCT03603496-d648a4ac
Transitional Tobacco Care Management (TTCM) vs eReferral to State Tobacco Quitline (QL): Tobacco Abstinence, Biochemically Confirmed
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Transitional Tobacco Care Management (TTCM) vs eReferral to State Tobacco Quitline (QL): Tobacco Abstinence, Biochemically Confirmed. Trial comparisons, record NCT03603496-d648a4ac. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03603496-d648a4ac
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.156 | 0.131 | 0.184 | wilson | |
| Risk in group 2 | 0.137 | 0.113 | 0.164 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0192 | -0.0177 | 0.0562 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.14 | 0.886 | 1.47 | log | |
| Odds ratio, group 1 over group 2 | 1.17 | 0.868 | 1.57 | log | |
| Number needed to treat, for one more participant with the outcome on Transitional Tobacco Care Management (TTCM) than on eReferral to State Tobacco Quitline (QL) | 51.9 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Transitional Tobacco Care Management (TTCM) | TTCM will provide 8 weeks of nicotine replacement therapy at hospital discharge and proactive contacts over 3 months delivered by automated IVR call. At each contact the patient is offered a return call from the hospital-based tobacco coach for counseling, medication advice, and coordination of care with the patient's outpatient health care team.~Transitional Tobacco Care Management (TTCM): TTCM will provide sustained care after discharge by offering (1) 8 weeks of nicotine replacement therapy at no cost provided at hospital discharge and (2) up to 7 proactive contacts over 3 months delivered by automated IVR call, supplemented by text messaging and email (patient choice). At each contact the patient is offered a return call from the hospital-based tobacco coach who offer counseling, medication advice, and coordination of care with the patient's outpatient health care team.~Nicotine replacement therapy: Up to 8 weeks of nicotine replacement therapy provided at no cost to the patient. | 110 | 706 | OG000 |
| Group 2 | eReferral to State Tobacco Quitline (QL) | Referral from hospital to the state Quitline will be made by the research team on behalf of each enrolled patient. Quitline staff will contact patient to offer up to 5 proactive telephone calls from a tobacco coach. Patient may also be eligible for NRT sample. Feedback from the quitline will be sent back to the patient's medical chart.~eReferral to State Tobacco Quitline (QL): Referral from hospital to the state Quitline will be made by the research team on behalf of each enrolled patient. Feedback from the Quitline will be included in the patient's medical chart.~Nicotine replacement therapy: Up to 8 weeks of nicotine replacement therapy provided at no cost to the patient. | 96 | 703 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Tobacco Abstinence, Biochemically Confirmed
- Description
Participant self-report of no use of any tobacco product (cigarettes, cigars, little cigars, pipes, smokeless tobacco product) in the past 7 days AND either a saliva sample with a cotinine concentration \<=10 ng/ml OR breath sample with a carbon monoxide concentration \<=9 ppm.
- Time frame
- 6 months after hospital discharge
- Population
Source ClinicalTrials.gov
Trial
- Title
- Post-Discharge Smoking Cessation Strategies: Helping HAND 4
- NCT number
- NCT03603496
- Phases
- PHASE4
- Conditions
- Smoking Cessation
- Interventions
- Transitional Tobacco Care Management (TTCM), eReferral to State Tobacco Quitline (QL), Nicotine replacement therapy
- Lead sponsor
- Massachusetts General Hospital
- Results first posted
- 2022-05-05
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03603496?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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