Trial · NCT03603496
Post-Discharge Smoking Cessation Strategies: Helping HAND 4
NCT03603496, Phase 4, Completed, Massachusetts General Hospital; results first posted 2022-05-05
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Post-Discharge Smoking Cessation Strategies: Helping HAND 4. Trials, record NCT03603496. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03603496
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Post-Discharge Smoking Cessation Strategies: Helping HAND 4
- NCT number
- NCT03603496
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 1,416 participants, actual
- Lead sponsor
- Massachusetts General Hospital
- Conditions
- Smoking Cessation
- Interventions
- Transitional Tobacco Care Management (TTCM), eReferral to State Tobacco Quitline (QL), Nicotine replacement therapy
- First posted
- 2018-07-27
- Last updated
- 2022-05-05
- Results first posted
- 2022-05-05
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Tobacco Abstinence, Biochemically Confirmed | 6 months after hospital discharge | Participant self-report of no use of any tobacco product (cigarettes, cigars, little cigars, pipes, smokeless tobacco product) in the past 7 days AND either a saliva sample with a cotinine concentration \<=10 ng/ml OR breath sample with a carbon monoxide concentration \<=9 ppm. |
| Secondary | Tobacco Abstinence, Self-report | 1 month after hospital discharge | Participant self-report of abstinence for the past 7 days from any tobacco product use (cigarettes, cigars, little cigars, pipes, smokeless tobacco product). |
| Secondary | Tobacco Abstinence, Self-report | 3 months after hospital discharge | Participant self-report of abstinence for the past 7 days from any tobacco product use (cigarettes, cigars, little cigars, pipes, smokeless tobacco product). |
| Secondary | Tobacco Abstinence, Self-report | 6 months after hospital discharge | Participant self-report of abstinence for the past 7 days from any tobacco product use (cigarettes, cigars, little cigars, pipes, smokeless tobacco product). |
| Secondary | Engagement in Cessation Treatment | 1 month after hospital discharge | Number of participants who report currently using tobacco treatment (defined as cessation medication or cessation counseling) at the 1 month post-discharge assessment. |
| Secondary | Engagement in Cessation Treatment | 3 months after hospital discharge | Number of participants who report currently using tobacco treatment (defined as cessation medication or cessation counseling) at 3 month post-discharge assessment |
| Secondary | Self-reported Continuous Tobacco Abstinence Since Hospital Discharge | 6 months follow-up | Number of participants who self-report having smoked no cigarettes and used no other tobacco products (cigars, little cigars, pipes, smokeless tobacco) since index hospital discharge |
Source ClinicalTrials.gov
Outcomes7
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Tobacco Abstinence, Biochemically Confirmed | 6 months after hospital discharge | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Tobacco Abstinence, Self-report | 1 month after hospital discharge | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Tobacco Abstinence, Self-report | 3 months after hospital discharge | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Tobacco Abstinence, Self-report | 6 months after hospital discharge | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Engagement in Cessation Treatment | 1 month after hospital discharge | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Engagement in Cessation Treatment | 3 months after hospital discharge | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Self-reported Continuous Tobacco Abstinence Since Hospital Discharge | 6 months follow-up | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group14
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Tobacco Abstinence, Biochemically Confirmed | Transitional Tobacco Care Management (TTCM) | 110 | Participants | ||
| Tobacco Abstinence, Biochemically Confirmed | eReferral to State Tobacco Quitline (QL) | 96 | Participants | ||
| Tobacco Abstinence, Self-report | Transitional Tobacco Care Management (TTCM) | 291 | Participants | ||
| Tobacco Abstinence, Self-report | eReferral to State Tobacco Quitline (QL) | 246 | Participants | ||
| Tobacco Abstinence, Self-report | Transitional Tobacco Care Management (TTCM) | 276 | Participants | ||
| Tobacco Abstinence, Self-report | eReferral to State Tobacco Quitline (QL) | 218 | Participants | ||
| Tobacco Abstinence, Self-report | Transitional Tobacco Care Management (TTCM) | 234 | Participants | ||
| Tobacco Abstinence, Self-report | eReferral to State Tobacco Quitline (QL) | 202 | Participants | ||
| Engagement in Cessation Treatment | Transitional Tobacco Care Management (TTCM) | 489 | Participants | ||
| Engagement in Cessation Treatment | eReferral to State Tobacco Quitline (QL) | 369 | Participants |
1 to 10 of 14Source ClinicalTrials.gov
See all 14 results by groupParticipant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Transitional Tobacco Care Management (TTCM) | 706 | |
| Overall Study | STARTED | eReferral to State Tobacco Quitline (QL) | 703 | |
| Overall Study | COMPLETED | Transitional Tobacco Care Management (TTCM) | 520 | |
| Overall Study | COMPLETED | eReferral to State Tobacco Quitline (QL) | 518 | |
| Overall Study | NOT COMPLETED | Transitional Tobacco Care Management (TTCM) | 186 | |
| Overall Study | NOT COMPLETED | eReferral to State Tobacco Quitline (QL) | 185 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Transitional Tobacco Care Management (TTCM) | 19 | 706 |
| Total, all-cause mortality | eReferral to State Tobacco Quitline (QL) | 24 | 703 |
| Total, other adverse events | Transitional Tobacco Care Management (TTCM) | 0 | 0 |
| Total, other adverse events | eReferral to State Tobacco Quitline (QL) | 0 | 0 |
| Total, serious adverse events | Transitional Tobacco Care Management (TTCM) | 0 | 0 |
| Total, serious adverse events | eReferral to State Tobacco Quitline (QL) | 0 | 0 |
Source ClinicalTrials.gov
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons8
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Transitional Tobacco Care Management (TTCM) vs eReferral to State Tobacco Quitline (QL): Tobacco Abstinence, Self-report | Trial comparisons |
| Transitional Tobacco Care Management (TTCM) vs eReferral to State Tobacco Quitline (QL): Engagement in Cessation Treatment | Trial comparisons |
| Transitional Tobacco Care Management (TTCM) vs eReferral to State Tobacco Quitline (QL): Tobacco Abstinence, Self-report | Trial comparisons |
| Transitional Tobacco Care Management (TTCM) vs eReferral to State Tobacco Quitline (QL): Tobacco Abstinence, Self-report | Trial comparisons |
| Transitional Tobacco Care Management (TTCM) vs eReferral to State Tobacco Quitline (QL): Engagement in Cessation Treatment | Trial comparisons |
| Transitional Tobacco Care Management (TTCM) vs eReferral to State Tobacco Quitline (QL): Self-reported Continuous Tobacco Abstinence Since Hospital Discharge | Trial comparisons |
| Transitional Tobacco Care Management (TTCM) vs eReferral to State Tobacco Quitline (QL): Tobacco Abstinence, Biochemically Confirmed | Trial comparisons |
| Transitional Tobacco Care Management (TTCM) vs eReferral to State Tobacco Quitline (QL): deaths from any cause | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03603496
GET https://conductscience.org/api/trials/v1/NCT03603496/registered