Comparison · NCT04026555-deaths
MEWS++ Monitoring vs Standard of Care Monitoring: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. MEWS++ Monitoring vs Standard of Care Monitoring: deaths from any cause. Trial comparisons, record NCT04026555-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04026555-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0699 | 0.058 | 0.084 | wilson | |
| Risk in group 2 | 0.0935 | 0.0785 | 0.111 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0236 | -0.0446 | -0.00305 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.748 | 0.581 | 0.963 | log | |
| Odds ratio, group 1 over group 2 | 0.729 | 0.553 | 0.96 | log | |
| Number needed to treat, for one fewer death from any cause on MEWS++ Monitoring than on Standard of Care Monitoring | 42.4 | 22.4 | 328 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: standard of care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | MEWS++ Monitoring | This consists of all the patients that will be receiving MEWS++ escalation monitoring and provider alerting.~MEWS++ Monitoring: Patient's electronic medical record data will undergo processing by a machine learning algorithm (MEWS++).~Predictor Score: A score predicting the likelihood that the patient will experience a deterioration in their clinical condition within six hours will be generated. If the prediction score exceeds a predetermined threshold, an alert will be sent to the provider. The alerting protocol is tiered, with both a low and high threshold. If the score is above the low threshold, nursing will be notified. If the score is above the high threshold, RRT will be notified. | 104 | 1,488 | EG000 |
| Group 2 | Standard of Care Monitoring | Patients in the control arm will have a score calculated but no alert will be sent.~Predictor Score: A score predicting the likelihood that the patient will experience a deterioration in their clinical condition within six hours will be generated. If the prediction score exceeds a predetermined threshold, an alert will be sent to the provider. The alerting protocol is tiered, with both a low and high threshold. If the score is above the low threshold, nursing will be notified. If the score is above the high threshold, RRT will be notified. | 117 | 1,252 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
Source ClinicalTrials.gov
Trial
- Title
- Realtime Streaming Clinical Use Engine for Medical Escalation
- NCT number
- NCT04026555
- Phases
- NA
- Conditions
- Clinical Deterioration, Hospital Medicine, Monitoring, Physiologic
- Interventions
- MEWS++ Monitoring, Predictor Score
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Results first posted
- 2025-01-14
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT04026555?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
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