Comparison · NCT05987709-d5cb4693
Guardant Shield Blood Test vs Standard of Care: Assess Colorectal Cancer Screening Completion
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Guardant Shield Blood Test vs Standard of Care: Assess Colorectal Cancer Screening Completion. Trial comparisons, record NCT05987709-d5cb4693. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT05987709-d5cb4693
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.305 | 0.277 | 0.334 | wilson | |
| Risk in group 2 | 0.13 | 0.11 | 0.152 | wilson | |
| Risk difference, group 1 minus group 2 | 0.175 | 0.14 | 0.21 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 2.35 | 1.95 | 2.83 | log | |
| Odds ratio, group 1 over group 2 | 2.94 | 2.34 | 3.7 | log | |
| Number needed to treat, for one more participant with the outcome on Guardant Shield Blood Test than on Standard of Care | 5.71 | 4.76 | 7.17 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: standard of care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Guardant Shield Blood Test | Patients will have the Guardant Shield blood test for colorectal cancer screening.~GuardantSHIELD Blood Test: The GuardantSHIELD CRC screening test is a commercially available test which works by finding signs of colorectal tumor in the blood of patients at average risk for CRC | 305 | 1,001 | OG000 |
| Group 2 | Standard of Care | Patients will have standard of care, which is a reminder to do their FIT test for colorectal cancer screening | 130 | 1,003 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Assess Colorectal Cancer Screening Completion
- Description
Assess the percentage who received any CRC screening test (blood draw, FIT or FIT-DNA, or flexible sigmoidoscopy or colonoscopy) within 3 months of eligibility determination among eligible individuals in the blood test and usual care groups.
- Time frame
- Within 3 months of patient identification
- Population
Source ClinicalTrials.gov
Trial
- Title
- Study of Colorectal Cancer Screening Options
- NCT number
- NCT05987709
- Phases
- NA
- Conditions
- Colon Cancer
- Interventions
- GuardantSHIELD Blood Test
- Lead sponsor
- Kaiser Permanente
- Results first posted
- 2025-12-16
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT05987709?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT05987709-d5cb4693