Comparison · NCT06027593-1c2acf1c
Pre-Intervention: Patients Diagnosed With Conditions of Interest During Study Period vs Post-Intervention: Patients Diagnosed With Conditions of Interest During Study Period: Guideline-concordant Antibiotic Choice Adult Pharyngitis
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Pre-Intervention: Patients Diagnosed With Conditions of Interest During Study Period vs Post-Intervention: Patients Diagnosed With Conditions of Interest During Study Period: Guideline-concordant Antibiotic Choice Adult Pharyngitis. Trial comparisons, record NCT06027593-1c2acf1c. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT06027593-1c2acf1c
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.844 | 0.682 | 0.931 | wilson | |
| Risk in group 2 | 0.914 | 0.863 | 0.947 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0705 | -0.235 | 0.0308 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.923 | 0.79 | 1.08 | log | |
| Odds ratio, group 1 over group 2 | 0.506 | 0.17 | 1.51 | log | |
Number needed to treat, for one fewer participant with the outcome on Pre-Intervention: Patients Diagnosed With Conditions of Interest During Study Period than on Post-Intervention: Patients Diagnosed With Conditions of Interest During Study Period | 14.2 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Pre-Intervention: Patients Diagnosed With Conditions of Interest During Study Period | Four population groups were included in the pre-intervention data: 1) adult inpatients with community acquired pneumonia; 2) pediatric inpatients with community acquired pneumonia; 3) adult outpatients with acute pharyngitis; and 4) pediatric outpatients with acute otitis media | 27 | 32 | OG000 |
| Group 2 | Post-Intervention: Patients Diagnosed With Conditions of Interest During Study Period | Four population groups were included in the post-intervention data: 1) adult inpatients with community acquired pneumonia; 2) pediatric inpatients with community acquired pneumonia; 3) adult outpatients with acute pharyngitis; and 4) pediatric outpatients with acute otitis media | 160 | 175 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Guideline-concordant Antibiotic Choice Adult Pharyngitis
- Description
Count of participants with adult pharyngitis with guideline-concordant antibiotic use for antibiotic choice. The count of participants with pharyngitis with guideline-concordant antibiotic use for this metric was divided by the total number of participants with pharyngitis to generate the percentage of participants receiving guideline-concordant antibiotic use for antibiotic choice. These proportions were compared for the group of participants in the pre intervention period (1 year) and the post intervention period (1 year). There were not individual participant level measures for this outcome.
- Time frame
- Pre-intervention and post-intervention, up to 2 years
- Population
Note: this metric of guideline-concordant antibiotic use was measured using a denominator of those who were prescribed antibiotics for adult pharyngitis (pre-intervention: 32 participants; post-intervention: 175 participants). The overall number of participants with adult pharyngitis (pre-intervention: 2,032 participants; post-intervention: 3,764 participants) was NOT used as the denominator for this reason.
Source ClinicalTrials.gov
Trial
- Title
- Using Electronically Derived Automated Reports of Appropriate Antibiotic Use to Inform Stewardship Interventions
- NCT number
- NCT06027593
- Phases
- NA
- Conditions
- Community-acquired Pneumonia, Acute Otitis Media, Pharyngitis
- Interventions
- Quasi experimental intervention
- Lead sponsor
- Children's Hospital of Philadelphia
- Results first posted
- 2025-11-14
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT06027593?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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