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Comparison · NCT06748040-deaths

Immediate Return of Results vs Delayed Return of Results: deaths from any cause

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Immediate Return of Results vs Delayed Return of Results: deaths from any cause. Trial comparisons, record NCT06748040-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT06748040-deaths

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.003150.001070.00921wilson
Risk in group 20.004340.001690.0111wilson
Risk difference, group 1 minus group 2-0.0012-0.008280.00543newcombe hybrid score
Risk ratio, group 1 over group 20.7250.1633.23log
Odds ratio, group 1 over group 20.7240.1623.24log
Number needed to treat, for one fewer death from any cause on Immediate Return of Results than on Delayed Return of Results837from the risk difference intervalthe interval includes no difference

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Immediate Return of ResultsImmediate return of pharmacogenetic (PGx) results to substudy (APOL1 negative/without APOL1-HR) participant.3953EG000
Group 2Delayed Return of ResultsDelayed return of pharmacogenetic (PGx) results to substudy (APOL1 negative/without APOL1-HR) participant until after the completion of the 6 month final study visit.4921EG001

Harm

What it counts
Total, all-cause mortality
Time frame

Source ClinicalTrials.gov

Trial

Title
Genetic Testing to Understand and Address Renal Disease Disparities Across the United States Pharmacogenetic Substudy
NCT number
NCT06748040
Phases
NA
Conditions
Chronic Kidney Disease, Hypertension
Interventions
Timing of return of results
Lead sponsor
Duke University
Results first posted
2025-04-30

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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