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85,013 comparisons from ClinicalTrials.gov.
Most participants first33,758 with no events in either group come last2,021 to 2,040 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| Cabotegravir vs TDF/FTC: Number of Participants With Documented Incident HIV Infections in Step 2 | 8 of 2,114 37 of 2,079 | -1.4 points -2.1 to -0.8 | 4,193 | NCT02720094 Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men |
| Omarigliptin 25 mg vs Placebo: Number of Participants With an Event of Stroke (Fatal and Non-fatal) | 32 of 2,092 34 of 2,100 | -0.1 points -0.9 to 0.7 | 4,192 | NCT01703208 A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018) |
| Omarigliptin 25 mg vs Placebo: Number of Participants With an Event of CV-Related Death | 37 of 2,092 35 of 2,100 | 0.1 points -0.7 to 0.9 | 4,192 | NCT01703208 A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018) |
| Omarigliptin 25 mg vs Placebo: Number of Participants With an Event of All-Cause Death | 64 of 2,092 50 of 2,100 | 0.7 points -0.3 to 1.7 | 4,192 | NCT01703208 A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018) |
| Omarigliptin 25 mg vs Placebo: Number of Participants With an Event of First Hospitalization for Heart Failure (Exploratory) | 20 of 2,092 33 of 2,100 | -0.6 points -1.3 to 0.1 | 4,192 | NCT01703208 A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018) |
| Omarigliptin 25 mg vs Placebo: Number of Participants With an Event of MACE (Confirmed CV-Related Death, Fatal and Nonfatal MI, and Fatal and Nonfatal Stroke) | 114 of 2,092 114 of 2,100 | 0.0 points -1.4 to 1.4 | 4,192 | NCT01703208 A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018) |
| Omarigliptin 25 mg vs Placebo: Number of Participants With an Event of First MI (Fatal and Non-fatal) | 52 of 2,092 60 of 2,100 | -0.4 points -1.4 to 0.6 | 4,192 | NCT01703208 A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018) |
| Omarigliptin 25 mg vs Placebo: serious adverse events | 512 of 2,092 503 of 2,100 | 0.5 points -2.1 to 3.1 | 4,192 | NCT01703208 A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018) |
| Omarigliptin 25 mg vs Placebo: Number of Participants With MACE-plus (Confirmed Cardiovascular [CV]-Related Death, Nonfatal Myocardial Infarction [MI], Nonfatal Stroke, or Hospitalization Due to Unstable Angina) | 66 of 2,090 70 of 2,100 | -0.2 points -1.3 to 0.9 | 4,190 | NCT01703208 A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018) |
| SMC021 vs Placebo: Number of Patients With New Vertebral Fractures | 94 of 2,064 99 of 2,125 | -0.1 points -1.4 to 1.2 | 4,189 | NCT00525798 A Study to Evaluate Oral Salmon Calcitonin in the Treatment of Osteoporosis in Postmenopausal Women Taking Calcium and Vitamin D |
| BCG-vaccine vs Control Children: Episodic Viral Wheeze | 211 of 2,108 195 of 2,081 | 0.6 points -1.2 to 2.4 | 4,189 | NCT01694108 Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children. |
| Universal PrEP Counselling vs Targeted PrEP Clinics: Partner With Known HIV Status | 1,680 of 2,155 1,648 of 2,030 | -3.2 points -5.7 to -0.8 | 4,185 | NCT03070600 PrEP Implementation for Mothers in Antenatal Care |
| BCG-vaccine vs Control Children: Food Allergy | 15 of 2,107 10 of 2,076 | 0.2 points -0.3 to 0.7 | 4,183 | NCT01694108 Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children. |
| Menhibrix Group vs ActHIB Group: Number of Subjects Reporting Adverse Events Resulting in Emergency Room (ER) Visits | 217 of 3,136 72 of 1,044 | 0.0 points -1.9 to 1.7 | 4,180 | NCT00289783 Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine |
| Menhibrix Group vs ActHIB Group: Number of Subjects Reporting Serious Adverse Events (SAEs) | 126 of 3,136 50 of 1,044 | -0.8 points -2.4 to 0.6 | 4,180 | NCT00289783 Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine |
| Menhibrix Group vs ActHIB Group: Number of Subjects Reporting Unsolicited Adverse Events (AEs) | 1,820 of 3,136 602 of 1,044 | 0.4 points -3.1 to 3.8 | 4,180 | NCT00289783 Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine |
| Menhibrix Group vs ActHIB Group: Number of Subjects Reporting New Onset of Chronic Illness(es) (NOCDs) | 163 of 3,136 52 of 1,044 | 0.2 points -1.4 to 1.6 | 4,180 | NCT00289783 Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine |
| Menhibrix Group vs ActHIB Group: Number of Subjects Reporting Adverse Events Resulting in Physicians (MD) Office Visits. | 1,336 of 3,136 433 of 1,044 | 1.1 points -2.3 to 4.6 | 4,180 | NCT00289783 Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine |
| Menhibrix Group vs ActHIB Group: Number of Subjects Reporting Rash | 470 of 3,136 154 of 1,044 | 0.2 points -2.3 to 2.6 | 4,180 | NCT00289783 Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine |
| Menhibrix Group vs ActHIB Group: serious adverse events | 126 of 3,136 50 of 1,044 | -0.8 points -2.4 to 0.6 | 4,180 | NCT00289783 Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine |
Code
curl "https://conductscience.org/api/comparisons/v1?page=102"
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=102
{
"data": {
"total": 85013,
"results": [
{
"id": "NCT02720094-75a50b74",
"title": "Cabotegravir vs TDF/FTC: Number of Participants With Documented Incident HIV Infections in Step 2",
"summary": "8 of 2114 against 37 of 2079; risk difference -1.4 points, 95% interval -2.1 to -0.8; NCT02720094, Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men",
"record": "/library/comparisons/NCT02720094-75a50b74",
"nct_id": "NCT02720094",
"kind": "outcome",
"participants": 4193,
"risk_difference": {
"value": -0.014012722621994145,
"lower": -0.020906483606117996,
"upper": -0.00792703023425435
},
"group_1": "8 of 2,114",
"group_2": "37 of 2,079",
"difference": "-1.4 points",
"interval": "-2.1 to -0.8",
"trial_title": "Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men"
},
{
"id": "NCT01703208-477b8423",
"title": "Omarigliptin 25 mg vs Placebo: Number of Participants With an Event of Stroke (Fatal and Non-fatal)",
"summary": "32 of 2092 against 34 of 2100; risk difference -0.1 points, 95% interval -0.9 to 0.7; NCT01703208, A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018)",
"record": "/library/comparisons/NCT01703208-477b8423",
"nct_id": "NCT01703208",
"kind": "outcome",
"participants": 4192,
"risk_difference": {
"value": -0.0008941090776654823,
"lower": -0.008641230101680646,
"upper": 0.006828865077302281
},
"group_1": "32 of 2,092",
"group_2": "34 of 2,100",
"difference": "-0.1 points",
"interval": "-0.9 to 0.7",
"trial_title": "A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018)"
}
],
"no_events": 33758,
"columns": [
{
"key": "title",
"label": "Comparison"
},
{
"key": "group_1",
"label": "With the outcome",
"under": "group_2"
},
{
"key": "difference",
"label": "Risk difference, 95% interval",
"under": "interval"
},
{
"key": "participants",
"label": "Participants"
},
{
"key": "nct_id",
"label": "Trial",
"under": "trial_title"
}
],
"order": "Most participants first",
"kinds": {
"all": 85013,
"outcome": 33568,
"serious-adverse-events": 31897,
"deaths": 19548
}
},
"release": "trial-comparisons-2026-03-23-0.1.0",
"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "Freely available. Acknowledgement requested"
},
{
"source": "ClinicalTrials.gov",
"license": "none stated",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "No license stated"
}
],
"next": "/api/comparisons/v1?page=103",
"request_id": "onA2Iis_SFDOIL93"
}Ask about these results. The first 10 go in the prompt.
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
NCBI Gene
One gene with its proteins, patents, drugs, trials, grants and papers.
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For software
Every answer on this page is also JSON, under /api/comparisons/v1. No key.
GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome
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