ConductScience.org, home

85,013 comparisons from ClinicalTrials.gov.

85,013 comparisons

Most participants first33,758 with no events in either group come last2,021 to 2,040 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Cabotegravir vs TDF/FTC: Number of Participants With Documented Incident HIV Infections in Step 28 of 2,114

37 of 2,079

-1.4 points

-2.1 to -0.8

4,193NCT02720094

Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men

Omarigliptin 25 mg vs Placebo: Number of Participants With an Event of Stroke (Fatal and Non-fatal)32 of 2,092

34 of 2,100

-0.1 points

-0.9 to 0.7

4,192NCT01703208

A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018)

Omarigliptin 25 mg vs Placebo: Number of Participants With an Event of CV-Related Death37 of 2,092

35 of 2,100

0.1 points

-0.7 to 0.9

4,192NCT01703208

A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018)

Omarigliptin 25 mg vs Placebo: Number of Participants With an Event of All-Cause Death64 of 2,092

50 of 2,100

0.7 points

-0.3 to 1.7

4,192NCT01703208

A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018)

Omarigliptin 25 mg vs Placebo: Number of Participants With an Event of First Hospitalization for Heart Failure (Exploratory)20 of 2,092

33 of 2,100

-0.6 points

-1.3 to 0.1

4,192NCT01703208

A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018)

Omarigliptin 25 mg vs Placebo: Number of Participants With an Event of MACE (Confirmed CV-Related Death, Fatal and Nonfatal MI, and Fatal and Nonfatal Stroke)114 of 2,092

114 of 2,100

0.0 points

-1.4 to 1.4

4,192NCT01703208

A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018)

Omarigliptin 25 mg vs Placebo: Number of Participants With an Event of First MI (Fatal and Non-fatal)52 of 2,092

60 of 2,100

-0.4 points

-1.4 to 0.6

4,192NCT01703208

A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018)

Omarigliptin 25 mg vs Placebo: serious adverse events512 of 2,092

503 of 2,100

0.5 points

-2.1 to 3.1

4,192NCT01703208

A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018)

Omarigliptin 25 mg vs Placebo: Number of Participants With MACE-plus (Confirmed Cardiovascular [CV]-Related Death, Nonfatal Myocardial Infarction [MI], Nonfatal Stroke, or Hospitalization Due to Unstable Angina)66 of 2,090

70 of 2,100

-0.2 points

-1.3 to 0.9

4,190NCT01703208

A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018)

SMC021 vs Placebo: Number of Patients With New Vertebral Fractures94 of 2,064

99 of 2,125

-0.1 points

-1.4 to 1.2

4,189NCT00525798

A Study to Evaluate Oral Salmon Calcitonin in the Treatment of Osteoporosis in Postmenopausal Women Taking Calcium and Vitamin D

BCG-vaccine vs Control Children: Episodic Viral Wheeze211 of 2,108

195 of 2,081

0.6 points

-1.2 to 2.4

4,189NCT01694108

Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children.

Universal PrEP Counselling vs Targeted PrEP Clinics: Partner With Known HIV Status1,680 of 2,155

1,648 of 2,030

-3.2 points

-5.7 to -0.8

4,185NCT03070600

PrEP Implementation for Mothers in Antenatal Care

BCG-vaccine vs Control Children: Food Allergy15 of 2,107

10 of 2,076

0.2 points

-0.3 to 0.7

4,183NCT01694108

Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children.

Menhibrix Group vs ActHIB Group: Number of Subjects Reporting Adverse Events Resulting in Emergency Room (ER) Visits217 of 3,136

72 of 1,044

0.0 points

-1.9 to 1.7

4,180NCT00289783

Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine

Menhibrix Group vs ActHIB Group: Number of Subjects Reporting Serious Adverse Events (SAEs)126 of 3,136

50 of 1,044

-0.8 points

-2.4 to 0.6

4,180NCT00289783

Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine

Menhibrix Group vs ActHIB Group: Number of Subjects Reporting Unsolicited Adverse Events (AEs)1,820 of 3,136

602 of 1,044

0.4 points

-3.1 to 3.8

4,180NCT00289783

Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine

Menhibrix Group vs ActHIB Group: Number of Subjects Reporting New Onset of Chronic Illness(es) (NOCDs)163 of 3,136

52 of 1,044

0.2 points

-1.4 to 1.6

4,180NCT00289783

Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine

Menhibrix Group vs ActHIB Group: Number of Subjects Reporting Adverse Events Resulting in Physicians (MD) Office Visits.1,336 of 3,136

433 of 1,044

1.1 points

-2.3 to 4.6

4,180NCT00289783

Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine

Menhibrix Group vs ActHIB Group: Number of Subjects Reporting Rash470 of 3,136

154 of 1,044

0.2 points

-2.3 to 2.6

4,180NCT00289783

Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine

Menhibrix Group vs ActHIB Group: serious adverse events126 of 3,136

50 of 1,044

-0.8 points

-2.4 to 0.6

4,180NCT00289783

Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

No key needed

Code

Show the call in
curl "https://conductscience.org/api/comparisons/v1?page=102"

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=102

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT02720094-75a50b74",
        "title": "Cabotegravir vs TDF/FTC: Number of Participants With Documented Incident HIV Infections in Step 2",
        "summary": "8 of 2114 against 37 of 2079; risk difference -1.4 points, 95% interval -2.1 to -0.8; NCT02720094, Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men",
        "record": "/library/comparisons/NCT02720094-75a50b74",
        "nct_id": "NCT02720094",
        "kind": "outcome",
        "participants": 4193,
        "risk_difference": {
          "value": -0.014012722621994145,
          "lower": -0.020906483606117996,
          "upper": -0.00792703023425435
        },
        "group_1": "8 of 2,114",
        "group_2": "37 of 2,079",
        "difference": "-1.4 points",
        "interval": "-2.1 to -0.8",
        "trial_title": "Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men"
      },
      {
        "id": "NCT01703208-477b8423",
        "title": "Omarigliptin 25 mg vs Placebo: Number of Participants With an Event of Stroke (Fatal and Non-fatal)",
        "summary": "32 of 2092 against 34 of 2100; risk difference -0.1 points, 95% interval -0.9 to 0.7; NCT01703208, A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018)",
        "record": "/library/comparisons/NCT01703208-477b8423",
        "nct_id": "NCT01703208",
        "kind": "outcome",
        "participants": 4192,
        "risk_difference": {
          "value": -0.0008941090776654823,
          "lower": -0.008641230101680646,
          "upper": 0.006828865077302281
        },
        "group_1": "32 of 2,092",
        "group_2": "34 of 2,100",
        "difference": "-0.1 points",
        "interval": "-0.9 to 0.7",
        "trial_title": "A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018)"
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "No license stated"
    }
  ],
  "next": "/api/comparisons/v1?page=103",
  "request_id": "onA2Iis_SFDOIL93"
}

Ask about these results. The first 10 go in the prompt.

About this data
Holds
85,013 comparisons
From ClinicalTrials.gov. Counted 10 Nov 2026.
Release
23 Mar 2026
trial-comparisons-2026-03-23-0.1.0
Checked
20 of 20 review comparisons traced to ClinicalTrials.gov, and all 510,078 numbers calculated again apart from the builder agree
Access
Open
No account. 60 calls a minute from one address.

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

Genes

NCBI Gene

One gene with its proteins, patents, drugs, trials, grants and papers.

Trials

ClinicalTrials.gov

Search clinical trials by condition, drug, outcome or NCT number, with the results each one posted.

Sequences

Patent publications

Paste a sequence and see the patents that disclose it.

Opens sequences.conductscience.org

For software

Read Trial comparisons from software.

Every answer on this page is also JSON, under /api/comparisons/v1. No key.

GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome

Ask an assistant

  • In FOURIER, how did serious adverse events compare between evolocumab and placebo?
  • Which metformin trials reported deaths, and what was the risk difference?
  • What was the number needed to treat for HELIOS-B's composite outcome?
  • Which placebo-controlled heart failure trials had the most participants?