Trials
ClinicalTrials.gov
Search clinical trials by condition, drug, outcome or NCT number, with the results each one posted.
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One record for each human gene in NCBI Gene. Each joins the gene to its reviewed protein, the patents that list that exact protein sequence, the drugs that act on it and their trials, and the NIH grants and papers about it.
11 sourcesgene-search-2026-11-11-0.1.0
A gene symbol, alias or name, an NCBI Gene, HGNC, Ensembl or UniProt ID, or a drug's name or ChEMBL ID.
193,990 genes from NCBI Gene. Counted 2026-11-11.
Try searching
Most papers first1 to 20 of 193,990
| Gene | NCBI Gene | Proteins | Patents | Drugs | Trials | NIH grants | Papers |
|---|---|---|---|---|---|---|---|
| TNF tumor necrosis factor | 7124 HGNC:11892 | 1 | 743 | 15 | 1,262 | 74,014 | 466,394 |
| INS insulin | 3630 HGNC:6081 | 1 | 544 | 0 | 0 | 60,160 | 398,943 |
| IL6 interleukin 6 | 3569 HGNC:6018 | 1 | 570 | 9 | 88 | 61,294 | 371,631 |
| CD4 CD4 molecule | 920 HGNC:1678 | 1 | 331 | 10 | 22 | 57,715 | 324,266 |
| CRP C-reactive protein | 1401 HGNC:2367 | 1 | 231 | 0 | 0 | 29,188 | 323,752 |
| TP53 tumor protein p53 | 7157 HGNC:11998 | 1 | 518 | 10 | 79 | 46,938 | 285,478 |
| AKT1 AKT serine/threonine kinase 1 | 207 HGNC:391 | 1 | 274 | 16 | 175 | 49,468 | 262,177 |
| NFKB1 nuclear factor kappa B subunit 1 | 4790 HGNC:7794 | 1 | 68 | 1 | 4 | 51,622 | 257,797 |
| ALB albumin | 213 HGNC:399 | 1 | 618 | 0 | 0 | 34,228 | 236,141 |
| IFNG interferon gamma | 3458 HGNC:5438 | 1 | 462 | 3 | 18 | 48,996 | 231,498 |
| CD8A CD8 subunit alpha | 925 HGNC:1706 | 1 | 565 | 0 | 0 | 44,314 | 228,019 |
| TGFB1 transforming growth factor beta 1 | 7040 HGNC:11766 | 1 | 245 | 5 | 111 | 49,789 | 225,278 |
| VEGFA vascular endothelial growth factor A | 7422 HGNC:12680 | 1 | 106 | 15 | 3,270 | 39,302 | 220,361 |
| IL1B interleukin 1 beta | 3553 HGNC:5992 | 1 | 349 | 5 | 139 | 44,185 | 207,658 |
| EGFR epidermal growth factor receptor | 1956 HGNC:3236 | 1 | 880 | 90 | 3,844 | 34,457 | 188,666 |
| GAPDH glyceraldehyde-3-phosphate dehydrogenase | 2597 HGNC:4141 | 1 | 193 | 0 | 0 | 46,614 | 170,218 |
| IL10 interleukin 10 | 3586 HGNC:5962 | 1 | 616 | 1 | 1 | 34,821 | 157,626 |
| ERBB2 erb-b2 receptor tyrosine kinase 2 | 2064 HGNC:3430 | 1 | 781 | 50 | 2,589 | 24,100 | 150,300 |
| MAPK1 mitogen-activated protein kinase 1 | 5594 HGNC:6871 | 1 | 236 | 6 | 25 | 38,003 | 149,001 |
| CXCL8 C-X-C motif chemokine ligand 8 | 3576 HGNC:6025 | 1 | 363 | 2 | 11 | 33,584 | 146,098 |
Response
The first 2 of this page's 20 results. GET /api/genes/v1
{
"data": {
"total": 193990,
"results": [
{
"id": "7124",
"title": "TNF: tumor necrosis factor",
"summary": "NCBI Gene 7124. 1 protein, 743 patents, 15 drugs, 1,262 trials, 74,014 NIH grants and 466,394 papers.",
"record": "/library/genes/7124",
"gene_id": 7124,
"symbol": "TNF",
"name": "tumor necrosis factor",
"hgnc_id": "HGNC:11892",
"counts": {
"proteins": 1,
"patents": 743,
"drugs": 15,
"trials": 1262,
"grants": 74014,
"papers": 466394
}
},
{
"id": "3630",
"title": "INS: insulin",
"summary": "NCBI Gene 3630. 1 protein, 544 patents, 0 drugs, 0 trials, 60,160 NIH grants and 398,943 papers.",
"record": "/library/genes/3630",
"gene_id": 3630,
"symbol": "INS",
"name": "insulin",
"hgnc_id": "HGNC:6081",
"counts": {
"proteins": 1,
"patents": 544,
"drugs": 0,
"trials": 0,
"grants": 60160,
"papers": 398943
}
}
],
"columns": [
{
"key": "symbol",
"label": "Gene",
"under": "name"
},
{
"key": "id",
"label": "NCBI Gene",
"under": "hgnc_id"
},
{
"key": "counts.proteins",
"label": "Proteins"
},
{
"key": "counts.patents",
"label": "Patents"
},
{
"key": "counts.drugs",
"label": "Drugs"
},
{
"key": "counts.trials",
"label": "Trials"
},
{
"key": "counts.grants",
"label": "NIH grants"
},
{
"key": "counts.papers",
"label": "Papers"
}
],
"order": "Most papers first"
},
"release": "gene-search-2026-11-11-0.1.0",
"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.",
"short": "Freely available. Acknowledgement requested"
},
{
"source": "ChEMBL, through Open Targets",
"license": "CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence",
"notice": null,
"short": "CC BY-SA 3.0"
},
{
"source": "ClinicalTrials.gov",
"license": "none stated",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.",
"short": "None stated"
},
{
"source": "EMBL-EBI's patent proteins",
"license": "EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: \"EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners\" and \"EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools.\" Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use",
"notice": null,
"short": "No added restrictions. Attribution expected"
},
{
"source": "GenBank's patent files",
"license": "GenBank's patent files. NCBI: \"NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted.\" Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/",
"notice": null,
"short": "No restrictions from NCBI. Submitters may hold rights"
},
{
"source": "HGNC",
"license": "CC0: https://www.genenames.org/about/license/",
"notice": null,
"short": "CC0"
},
{
"source": "NCBI Gene",
"license": "None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/",
"notice": null,
"short": "None named. Public domain as US government information"
},
{
"source": "NIH's project files and grant-paper links",
"license": "Public domain (NIH RePORTER)",
"notice": null,
"short": "Public domain"
},
{
"source": "Open Targets",
"license": "CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence",
"notice": null,
"short": "CC0 1.0"
},
{
"source": "PubTator 3",
"license": "Public domain",
"notice": null,
"short": "Public domain"
},
{
"source": "UniProt",
"license": "CC BY 4.0. UniProt's licence file: \"All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy.\" UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license",
"notice": null,
"short": "CC BY 4.0"
}
],
"next": "/api/genes/v1?page=2",
"request_id": "idJ-BhAvQOjrw0yO"
}The 6 lists in a gene's record, and how many genes have each.
Reviewed human proteins whose Swiss-Prot entry states the gene.
20,42810.5% of genes
Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.
19,93110.3% of genes
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
1,5550.8% of genes
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
1,4940.8% of genes
NIH projects whose papers are about the gene, through NIH's grant-paper links.
87,85545.3% of genes
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
154,95079.9% of genes
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov
Search clinical trials by condition, drug, outcome or NCT number, with the results each one posted.
ClinicalTrials.gov
Comparisons of the groups of clinical trials, such as a risk ratio or a number needed to treat, calculated from the counts each trial posted.
Patent publications
Paste a sequence and see the patents that disclose it.
For invited accounts.
Opens sequences.conductscience.org
For software
Every answer on this page is also JSON, under /api/genes/v1. No key.
GET https://conductscience.org/api/genes/v1?q=p53
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