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Genes

One record for each human gene in NCBI Gene. Each joins the gene to its reviewed protein, the patents that list that exact protein sequence, the drugs that act on it and their trials, and the NIH grants and papers about it.

11 sourcesgene-search-2026-11-11-0.1.0

Search Genes.

A gene symbol, alias or name, an NCBI Gene, HGNC, Ensembl or UniProt ID, or a drug's name or ChEMBL ID.

193,990 genes from NCBI Gene. Counted 2026-11-11.

Try searching

Genes 193,990

Most papers first1 to 20 of 193,990

Show the results as
GeneNCBI GeneProteinsPatentsDrugsTrialsNIH grantsPapers
TNF

tumor necrosis factor

7124

HGNC:11892

1743151,26274,014466,394
INS

insulin

3630

HGNC:6081

15440060,160398,943
IL6

interleukin 6

3569

HGNC:6018

157098861,294371,631
CD4

CD4 molecule

920

HGNC:1678

1331102257,715324,266
CRP

C-reactive protein

1401

HGNC:2367

12310029,188323,752
TP53

tumor protein p53

7157

HGNC:11998

1518107946,938285,478
AKT1

AKT serine/threonine kinase 1

207

HGNC:391

12741617549,468262,177
NFKB1

nuclear factor kappa B subunit 1

4790

HGNC:7794

1681451,622257,797
ALB

albumin

213

HGNC:399

16180034,228236,141
IFNG

interferon gamma

3458

HGNC:5438

146231848,996231,498
CD8A

CD8 subunit alpha

925

HGNC:1706

15650044,314228,019
TGFB1

transforming growth factor beta 1

7040

HGNC:11766

1245511149,789225,278
VEGFA

vascular endothelial growth factor A

7422

HGNC:12680

1106153,27039,302220,361
IL1B

interleukin 1 beta

3553

HGNC:5992

1349513944,185207,658
EGFR

epidermal growth factor receptor

1956

HGNC:3236

1880903,84434,457188,666
GAPDH

glyceraldehyde-3-phosphate dehydrogenase

2597

HGNC:4141

11930046,614170,218
IL10

interleukin 10

3586

HGNC:5962

16161134,821157,626
ERBB2

erb-b2 receptor tyrosine kinase 2

2064

HGNC:3430

1781502,58924,100150,300
MAPK1

mitogen-activated protein kinase 1

5594

HGNC:6871

123662538,003149,001
CXCL8

C-X-C motif chemokine ligand 8

3576

HGNC:6025

136321133,584146,098

Request

GET /api/genes/v1

A gene symbol, alias or name, an NCBI Gene, HGNC, Ensembl or UniProt ID, or a drug's name or ChEMBL ID.

No key needed

Response

The first 2 of this page's 20 results. GET /api/genes/v1

{
  "data": {
    "total": 193990,
    "results": [
      {
        "id": "7124",
        "title": "TNF: tumor necrosis factor",
        "summary": "NCBI Gene 7124. 1 protein, 743 patents, 15 drugs, 1,262 trials, 74,014 NIH grants and 466,394 papers.",
        "record": "/library/genes/7124",
        "gene_id": 7124,
        "symbol": "TNF",
        "name": "tumor necrosis factor",
        "hgnc_id": "HGNC:11892",
        "counts": {
          "proteins": 1,
          "patents": 743,
          "drugs": 15,
          "trials": 1262,
          "grants": 74014,
          "papers": 466394
        }
      },
      {
        "id": "3630",
        "title": "INS: insulin",
        "summary": "NCBI Gene 3630. 1 protein, 544 patents, 0 drugs, 0 trials, 60,160 NIH grants and 398,943 papers.",
        "record": "/library/genes/3630",
        "gene_id": 3630,
        "symbol": "INS",
        "name": "insulin",
        "hgnc_id": "HGNC:6081",
        "counts": {
          "proteins": 1,
          "patents": 544,
          "drugs": 0,
          "trials": 0,
          "grants": 60160,
          "papers": 398943
        }
      }
    ],
    "columns": [
      {
        "key": "symbol",
        "label": "Gene",
        "under": "name"
      },
      {
        "key": "id",
        "label": "NCBI Gene",
        "under": "hgnc_id"
      },
      {
        "key": "counts.proteins",
        "label": "Proteins"
      },
      {
        "key": "counts.patents",
        "label": "Patents"
      },
      {
        "key": "counts.drugs",
        "label": "Drugs"
      },
      {
        "key": "counts.trials",
        "label": "Trials"
      },
      {
        "key": "counts.grants",
        "label": "NIH grants"
      },
      {
        "key": "counts.papers",
        "label": "Papers"
      }
    ],
    "order": "Most papers first"
  },
  "release": "gene-search-2026-11-11-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ChEMBL, through Open Targets",
      "license": "CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence",
      "notice": null,
      "short": "CC BY-SA 3.0"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.",
      "short": "None stated"
    },
    {
      "source": "EMBL-EBI's patent proteins",
      "license": "EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: \"EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners\" and \"EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools.\" Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use",
      "notice": null,
      "short": "No added restrictions. Attribution expected"
    },
    {
      "source": "GenBank's patent files",
      "license": "GenBank's patent files. NCBI: \"NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted.\" Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/",
      "notice": null,
      "short": "No restrictions from NCBI. Submitters may hold rights"
    },
    {
      "source": "HGNC",
      "license": "CC0: https://www.genenames.org/about/license/",
      "notice": null,
      "short": "CC0"
    },
    {
      "source": "NCBI Gene",
      "license": "None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/",
      "notice": null,
      "short": "None named. Public domain as US government information"
    },
    {
      "source": "NIH's project files and grant-paper links",
      "license": "Public domain (NIH RePORTER)",
      "notice": null,
      "short": "Public domain"
    },
    {
      "source": "Open Targets",
      "license": "CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence",
      "notice": null,
      "short": "CC0 1.0"
    },
    {
      "source": "PubTator 3",
      "license": "Public domain",
      "notice": null,
      "short": "Public domain"
    },
    {
      "source": "UniProt",
      "license": "CC BY 4.0. UniProt's licence file: \"All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy.\" UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license",
      "notice": null,
      "short": "CC BY 4.0"
    }
  ],
  "next": "/api/genes/v1?page=2",
  "request_id": "idJ-BhAvQOjrw0yO"
}
gene-search-2026-11-11-0.1.0Next page

What it holds

Holds
193,990 genes
From NCBI Gene. Counted 11 Nov 2026.
Release
11 Nov 2026
gene-search-2026-11-11-0.1.0
Checked
20 of 20 review genes traced to the raw source files, every checked row right
Access
Open
No account. 60 calls a minute from one address.

The 6 lists in a gene's record, and how many genes have each.

  • Proteins

    Reviewed human proteins whose Swiss-Prot entry states the gene.

    20,42810.5% of genes

  • Patents

    Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

    19,93110.3% of genes

  • Drugs

    Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

    1,5550.8% of genes

  • Trials

    Trials of those drugs. A trial joins the gene only through a drug that acts on it.

    1,4940.8% of genes

  • NIH grants

    NIH projects whose papers are about the gene, through NIH's grant-paper links.

    87,85545.3% of genes

  • Papers

    Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

    154,95079.9% of genes

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

Trials

ClinicalTrials.gov

Search clinical trials by condition, drug, outcome or NCT number, with the results each one posted.

Open611,552 trials2026-11-12

Trial comparisons

ClinicalTrials.gov

Comparisons of the groups of clinical trials, such as a risk ratio or a number needed to treat, calculated from the counts each trial posted.

Open85,013 comparisons2026-11-10

Sequences

Patent publications

Paste a sequence and see the patents that disclose it.

For invited accounts.

Opens sequences.conductscience.org

By invitation39,249,078 sequences2026-11-05

For software

Read Genes from software.

Every answer on this page is also JSON, under /api/genes/v1. No key.

GET https://conductscience.org/api/genes/v1?q=p53

Ask an assistant

  • Which drugs act on PCSK9, and which of their trials posted results?
  • How many patents list the exact protein sequence of TP53?
  • Which genes does evolocumab act on?
  • Which NIH grants have the most papers about APOE?