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IFNG: interferon gamma

1 protein, 462 patents, 3 drugs, 18 trials, 48,996 NIH grants and 231,498 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIFNGHGNC
Nameinterferon gammaHGNC
NCBI Gene ID3458NCBI Gene
HGNC IDHGNC:5438HGNC
EnsemblENSG00000111537NCBI Gene
AliasesIFG, IFI, IMD69NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P01579Interferon gamma1668Ensembl, GeneID, HGNCUniProt

Patents 462

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026177163 A2026-08-275P01579Espacenet
EP 4791437 A12026-08-19167P01579Espacenet
WO 2026167214 A12026-08-13120P01579Espacenet
US 12653852 B22026-06-1641P01579Espacenet
EP 4750803 A12026-06-031P01579Espacenet
US 12617829 B22026-05-0583P01579Espacenet
JP 2026062601 A52026-04-2410P01579Espacenet
EP 4724500 A22026-04-15313P01579Espacenet
JP 2026048868 A2026-03-1785P01579Espacenet
EP 4705273 A22026-03-11542P01579Espacenet

Drugs 3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AMG-811CHEMBL2109450Interferon gamma inhibitorINHIBITORChEMBL
EMAPALUMABCHEMBL3989977Interferon gamma inhibitorINHIBITORChEMBL
FONTOLIZUMABCHEMBL2108459Interferon gamma inhibitorINHIBITORChEMBL

Trials 18

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07486869EMAPALUMABPHASE2ClinicalTrials.gov
NCT06951971EMAPALUMABPHASE2/PHASE3ClinicalTrials.gov
NCT06694701EMAPALUMABPHASE2ClinicalTrials.gov
NCT06430788EMAPALUMABPHASE2ClinicalTrials.gov
NCT06038422EMAPALUMABPHASE3ClinicalTrials.gov
NCT05787574EMAPALUMABPHASE2ClinicalTrials.gov
NCT05744063EMAPALUMABPHASE42026-03-13ClinicalTrials.gov
NCT05463133EMAPALUMABPHASE1/PHASE2ClinicalTrials.gov
NCT05001737EMAPALUMABPHASE32026-02-19ClinicalTrials.gov
NCT03985423EMAPALUMABPHASE2/PHASE32023-10-06ClinicalTrials.gov

NIH grants 48996

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant7192,025NIH's project files
P30CA016672Cancer Center Support Grant6262,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award3122,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program2212,025NIH's project files
P30CA016058Cancer Center Support Grant2072,025NIH's project files
P30AI027763UCSF-Bay Area Center for AIDS Research1862,025NIH's project files
P30CA006973Regional Oncology Research Center1802,025NIH's project files
P30CA047904Cancer Center Support Grant1802,025NIH's project files
P30AI060354Harvard University Center for AIDS Research1762,025NIH's project files
P51OD011132Emory National Primate Research Center1712,025NIH's project files

Papers 231498

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826830PubTator, text miningPubMed
42826173PubTator, text miningPubMed
42825992PubTator, text miningPubMed
42825916PubTator, text miningPubMed
42825912PubTator, text miningPubMed
42825901PubTator, text miningPubMed
42825488PubTator, text miningPubMed
42825403PubTator, text miningPubMed
42824734PubTator, text miningPubMed
42824414PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license