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85,013 comparisons from ClinicalTrials.gov.
Most participants first33,758 with no events in either group come last2,361 to 2,380 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| Doxorubicin + Cyclophosphamide Followed by Docetaxel (AC -> T) vs Docetaxel + Doxorubicin and Cyclophosphamide (TAC): Death From Any Cause (Overall Survival) | 187 of 1,649 202 of 1,649 | -0.9 points -3.1 to 1.3 | 3,298 | NCT00312208 Docetaxel in Breast Cancer |
| Group 1 rLP2086 vs Group 2 Saline: serious adverse events | 33 of 2,471 11 of 822 | -0.0 points -1.1 to 0.8 | 3,293 | NCT01352845 A Trial to Assess the Safety, Tolerability, and Immunogenicity of Bivalent rLP2086 Vaccine When Given to Healthy Young Adults Aged >=18 to <26 Years. |
| Randomized Blinded Phase: LEN + Placebo-to-match (PTM) F/TDF vs Randomized Blinded Phase: Placebo LEN + F/TDF: deaths from any cause | 4 of 2,195 2 of 1,097 | -0.0 points -0.5 to 0.3 | 3,292 | NCT04925752 Pre-Exposure Prophylaxis Study of Lenacapavir in Cisgender Men, Transgender Women, Transgender Men, and Gender Nonbinary People at Risk for HIV Infection |
| Proton Pump Inhibitor (PPI) vs Normal Saline: Number of Participants With Clinically Important GI Bleeding, Pneumonia, Clostridium Difficile Infection or Acute Myocardial Ischemia | 360 of 1,644 372 of 1,647 | -0.7 points -3.5 to 2.2 | 3,291 | NCT02467621 Stress Ulcer Prophylaxis in the Intensive Care Unit |
| Proton Pump Inhibitor (PPI) vs Normal Saline: Number of Participants With One or More Infectious Adverse Events | 276 of 1,644 279 of 1,647 | -0.2 points -2.7 to 2.4 | 3,291 | NCT02467621 Stress Ulcer Prophylaxis in the Intensive Care Unit |
| Proton Pump Inhibitor (PPI) vs Normal Saline: Number of Participants With Clinically Important GI Bleeding | 41 of 1,644 69 of 1,647 | -1.7 points -3.0 to -0.5 | 3,291 | NCT02467621 Stress Ulcer Prophylaxis in the Intensive Care Unit |
| Proton Pump Inhibitor (PPI) vs Normal Saline: Mortality | 510 of 1,642 499 of 1,640 | 0.6 points -2.5 to 3.8 | 3,282 | NCT02467621 Stress Ulcer Prophylaxis in the Intensive Care Unit |
| Randomized Blinded Phase: LEN + Placebo-to-match (PTM) F/TDF vs Randomized Blinded Phase: Placebo LEN + F/TDF: serious adverse events | 71 of 2,183 43 of 1,088 | -0.7 points -2.2 to 0.6 | 3,271 | NCT04925752 Pre-Exposure Prophylaxis Study of Lenacapavir in Cisgender Men, Transgender Women, Transgender Men, and Gender Nonbinary People at Risk for HIV Infection |
| Doxorubicin + Cyclophosphamide Followed by Docetaxel (AC -> T) vs Docetaxel + Doxorubicin and Cyclophosphamide (TAC): serious adverse events | 331 of 1,634 520 of 1,635 | -11.5 points -14.5 to -8.6 | 3,269 | NCT00312208 Docetaxel in Breast Cancer |
| Proton Pump Inhibitor (PPI) vs Normal Saline: deaths from any cause | 610 of 1,635 601 of 1,626 | 0.3 points -3.0 to 3.7 | 3,261 | NCT02467621 Stress Ulcer Prophylaxis in the Intensive Care Unit |
| Proton Pump Inhibitor (PPI) vs Normal Saline: Mortality | 610 of 1,635 601 of 1,626 | 0.3 points -3.0 to 3.7 | 3,261 | NCT02467621 Stress Ulcer Prophylaxis in the Intensive Care Unit |
| Toujeo vs Standard of Care Basal Insulin: deaths from any cause | 7 of 1,637 4 of 1,621 | 0.2 points -0.3 to 0.7 | 3,258 | NCT02451137 A "Real World" Trial to Determine Efficacy and Health Outcomes of Toujeo (ACHIEVE CONTROL REAL LIFE STUDY PROGRAM) |
| Toujeo vs Standard of Care Basal Insulin: serious adverse events | 161 of 1,637 165 of 1,621 | -0.3 points -2.4 to 1.7 | 3,258 | NCT02451137 A "Real World" Trial to Determine Efficacy and Health Outcomes of Toujeo (ACHIEVE CONTROL REAL LIFE STUDY PROGRAM) |
| Varenicline - With Concomitant Drugs vs Varenicline - Without Concomitant Drugs: Risk Factors for the Frequency of Treatment Related Adverse Events - Concomitant Drugs. | 289 of 738 424 of 2,519 | 22.3 points 18.6 to 26.2 | 3,257 | NCT00772941 Drug Use Investigation Of Varenicline (Regulatory Post Marketing Commitment Plan) |
| Varenicline - With Concomitant Therapies vs Varenicline - Without Concomitant Therapies: Risk Factors for the Frequency of Treatment Related Adverse Events - Concomitant Therapies. | 45 of 101 668 of 3,156 | 23.4 points 14.0 to 33.2 | 3,257 | NCT00772941 Drug Use Investigation Of Varenicline (Regulatory Post Marketing Commitment Plan) |
| Male vs Female: Risk Factors for the Frequency of Treatment Related Adverse Events - Gender. | 377 of 2,179 336 of 1,078 | -13.9 points -17.1 to -10.7 | 3,257 | NCT00772941 Drug Use Investigation Of Varenicline (Regulatory Post Marketing Commitment Plan) |
| <65 Years vs >=65 Years: Risk Factors for the Frequency of Treatment Related Adverse Events - Age. | 571 of 2,768 142 of 489 | -8.4 points -12.8 to -4.3 | 3,257 | NCT00772941 Drug Use Investigation Of Varenicline (Regulatory Post Marketing Commitment Plan) |
| Varenicline - With Chronic Obstructive Pulmonary Disease vs Varenicline - Without Chronic Obstructive Pulmonary Disease: Risk Factors for the Frequency of Treatment Related Adverse Events - Chronic Obstructive Pulmonary Disease as a Complication. | 23 of 46 690 of 3,211 | 28.5 points 14.6 to 42.5 | 3,257 | NCT00772941 Drug Use Investigation Of Varenicline (Regulatory Post Marketing Commitment Plan) |
| Standard Practice vs Personal Hand Hygiene Device: Number of Participants With Postoperative Healthcare Acquired Infections | 108 of 1,620 116 of 1,636 | -0.4 points -2.2 to 1.3 | 3,256 | NCT02252562 Hand Hygiene and Hospital Acquired Infections |
| Standard Practice vs Personal Hand Hygiene Device: Mortality | 6 of 1,620 7 of 1,636 | -0.1 points -0.6 to 0.4 | 3,256 | NCT02252562 Hand Hygiene and Hospital Acquired Infections |
Code
curl "https://conductscience.org/api/comparisons/v1?page=119"
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=119
{
"data": {
"total": 85013,
"results": [
{
"id": "NCT00312208-f73a5fb6",
"title": "Doxorubicin + Cyclophosphamide Followed by Docetaxel (AC -> T) vs Docetaxel + Doxorubicin and Cyclophosphamide (TAC): Death From Any Cause (Overall Survival)",
"summary": "187 of 1649 against 202 of 1649; risk difference -0.9 points, 95% interval -3.1 to 1.3; NCT00312208, Docetaxel in Breast Cancer",
"record": "/library/comparisons/NCT00312208-f73a5fb6",
"nct_id": "NCT00312208",
"kind": "outcome",
"participants": 3298,
"risk_difference": {
"value": -0.009096422073984228,
"lower": -0.031162673666971907,
"upper": 0.012958015905097924
},
"group_1": "187 of 1,649",
"group_2": "202 of 1,649",
"difference": "-0.9 points",
"interval": "-3.1 to 1.3",
"trial_title": "Docetaxel in Breast Cancer"
},
{
"id": "NCT01352845-sae",
"title": "Group 1 rLP2086 vs Group 2 Saline: serious adverse events",
"summary": "33 of 2471 against 11 of 822; risk difference -0.0 points, 95% interval -1.1 to 0.8; NCT01352845, A Trial to Assess the Safety, Tolerability, and Immunogenicity of Bivalent rLP2086 Vaccine When Given to Healthy Young Adults Aged >=18 to <26 Years.",
"record": "/library/comparisons/NCT01352845-sae",
"nct_id": "NCT01352845",
"kind": "serious-adverse-events",
"participants": 3293,
"risk_difference": {
"value": -0.00002707809618336665,
"lower": -0.011129155741582934,
"upper": 0.007926199721466975
},
"group_1": "33 of 2,471",
"group_2": "11 of 822",
"difference": "-0.0 points",
"interval": "-1.1 to 0.8",
"trial_title": "A Trial to Assess the Safety, Tolerability, and Immunogenicity of Bivalent rLP2086 Vaccine When Given to Healthy Young Adults Aged >=18 to <26 Years."
}
],
"no_events": 33758,
"columns": [
{
"key": "title",
"label": "Comparison"
},
{
"key": "group_1",
"label": "With the outcome",
"under": "group_2"
},
{
"key": "difference",
"label": "Risk difference, 95% interval",
"under": "interval"
},
{
"key": "participants",
"label": "Participants"
},
{
"key": "nct_id",
"label": "Trial",
"under": "trial_title"
}
],
"order": "Most participants first",
"kinds": {
"all": 85013,
"outcome": 33568,
"serious-adverse-events": 31897,
"deaths": 19548
}
},
"release": "trial-comparisons-2026-03-23-0.1.0",
"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "Freely available. Acknowledgement requested"
},
{
"source": "ClinicalTrials.gov",
"license": "none stated",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "No license stated"
}
],
"next": "/api/comparisons/v1?page=120",
"request_id": "ZVnjFZYhpXXTidcP"
}Ask about these results. The first 10 go in the prompt.
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
NCBI Gene
One gene with its proteins, patents, drugs, trials, grants and papers.
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For software
Every answer on this page is also JSON, under /api/comparisons/v1. No key.
GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome
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