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85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.

85,013 comparisons

Most participants first33,758 with no events in either group come last221 to 240 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
CVnCoV 12 μg Vaccine vs Placebo: Number of Participants Who Experienced a Fatal SAE11 of 19,787

12 of 19,753

-0.0 points

-0.1 to 0.0

39,540NCT04652102

A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older

CVnCoV 12 μg Vaccine vs Placebo: deaths from any cause17 of 19,787

14 of 19,753

0.0 points

-0.0 to 0.1

39,540NCT04652102

A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older

CVnCoV 12 μg Vaccine vs Placebo: serious adverse events149 of 19,787

111 of 19,753

0.2 points

0.0 to 0.4

39,540NCT04652102

A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older

Cases vs Controls: Number of New Onset Skin Cancers in the White Ethnicity Subgroup103 of 7,932

563 of 31,118

-0.5 points

-0.8 to -0.2

39,050NCT04969419

Incidence of Melanoma and Non-melanoma Skin Cancer in People With Vitiligo

Double-blind Phase: Ad26.COV2.S 5*10^10 vp vs Double-blind Phase: Placebo: Number of Participants With First Occurrence of Molecularly Confirmed Severe/Critical COVID-19 With Seronegative Status With Onset at Least 14 Days After Double-blind Vaccination on Day 1 (Day 15): Double-blind Phase56 of 19,400

205 of 19,398

-0.8 points

-0.9 to -0.6

38,798NCT04505722

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants

Double-blind Phase: Ad26.COV2.S 5*10^10 vp vs Double-blind Phase: Placebo: Number of Participants With Burden of Disease (BOD) Based on First Occurrence of Molecularly Confirmed Symptomatic COVID-19 (Double Blind Phase)495 of 19,400

1,082 of 19,398

-3.0 points

-3.4 to -2.6

38,798NCT04505722

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants

Double-blind Phase: Ad26.COV2.S 5*10^10 vp vs Double-blind Phase: Placebo: Number of Participants With First Occurrence of Molecularly Confirmed Mild COVID-19 (Double Blind Phase11 of 19,400

15 of 19,398

-0.0 points

-0.1 to 0.0

38,798NCT04505722

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants

Double-blind Phase: Ad26.COV2.S 5*10^10 vp vs Double-blind Phase: Placebo: Number of Participants With First Occurrence of COVID-19 Requiring Medical Intervention (Double Blind Phase)18 of 19,400

74 of 19,398

-0.3 points

-0.4 to -0.2

38,798NCT04505722

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants

Double-blind Phase: Ad26.COV2.S 5*10^10 vp vs Double-blind Phase: Placebo: Number of Participants With First Occurrence of Molecularly Confirmed COVID-19 Defined by the US Food and Drug Administration (FDA) Harmonized Case Definition (Double Blind Phase)492 of 19,400

1,067 of 19,398

-3.0 points

-3.4 to -2.6

38,798NCT04505722

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants

Double-blind Phase: Ad26.COV2.S 5*10^10 vp vs Double-blind Phase: Placebo: Number of Participants With First Occurrence of SARS-CoV-2 Infection (Serologically and/or Molecularly Confirmed) (Double Blind Phase)1,038 of 19,113

1,699 of 18,924

-3.5 points

-4.1 to -3.0

38,037NCT04505722

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants

Double-blind Phase: Ad26.COV2.S 5*10^10 vp vs Double-blind Phase: Placebo: Number of Participants With SARS-CoV-2 Seroconversion Based on Antibodies to N Protein Using ELISA and/or SARS-CoV-2 Immunoglobulin Assay (Double Blind Phase)550 of 19,113

724 of 18,924

-0.9 points

-1.3 to -0.6

38,037NCT04505722

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants

Double-blind Phase: Ad26.COV2.S 5*10^10 vp vs Double-blind Phase: Placebo: Number of Participants With First Occurrence of COVID-19 Requiring Medical Intervention (Double Blind Phase)16 of 19,113

64 of 18,924

-0.3 points

-0.4 to -0.2

38,037NCT04505722

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants

Double-blind Phase: Ad26.COV2.S 5*10^10 vp vs Double-blind Phase: Placebo: Number of Participants With First Occurrence of Molecularly Confirmed Mild COVID-19 (Double Blind Phase)10 of 19,113

12 of 18,924

-0.0 points

-0.1 to 0.0

38,037NCT04505722

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants

Double-blind Phase: Ad26.COV2.S 5*10^10 vp vs Double-blind Phase: Placebo: Number of Participants With First Occurrence of Molecularly Confirmed Severe/Critical COVID-19 With Seronegative Status With Onset at Least 28 Days After Double-blind Vaccination on Day 1 (Day 29): Double-blind Phase46 of 19,113

176 of 18,924

-0.7 points

-0.8 to -0.5

38,037NCT04505722

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants

Double-blind Phase: Ad26.COV2.S 5*10^10 vp vs Double-blind Phase: Placebo: Number of Participants With First Occurrence of Molecularly Confirmed COVID-19 Defined by the US Food and Drug Administration (FDA) Harmonized Case Definition (Double Blind Phase)441 of 19,113

884 of 18,924

-2.4 points

-2.7 to -2.0

38,037NCT04505722

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants

Double-blind Phase: Ad26.COV2.S 5*10^10 vp vs Double-blind Phase: Placebo: Number of Participants With BOD Based on First Occurrence of Molecularly Confirmed Symptomatic COVID-19 (Double Blind Phase)443 of 19,113

895 of 18,924

-2.4 points

-2.8 to -2.0

38,037NCT04505722

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants

Double-blind Phase: Ad26.COV2.S 5*10^10 vp vs Double-blind Phase: Placebo: Number of Participants With Asymptomatic Infection Detected by RT-PCR at the Time of the Month 6/Unblinding Visit (Double Blind Phase)10 of 19,113

12 of 18,924

-0.0 points

-0.1 to 0.0

38,037NCT04505722

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants

Cases vs Controls: Number of New Onset Skin Cancers in the Most Deprived Subgroup46 of 7,681

345 of 30,325

-0.5 points

-0.7 to -0.3

38,006NCT04969419

Incidence of Melanoma and Non-melanoma Skin Cancer in People With Vitiligo

Chlorhexidine Cord Care vs Dry Cord Care: deaths from any cause282 of 18,510

263 of 19,346

0.2 points

-0.1 to 0.4

37,856NCT01241318

Zambia Chlorhexidine Application Trial

People With Crohn's Disease (Cases) vs People Without Crohn's Disease (Controls): Prevalence of Depressive Episodes (Crohn's Disease)431 of 7,557

1,233 of 30,228

1.6 points

1.1 to 2.2

37,785NCT03836612

Healthcare Resource Utilisation, Common Mental Health Problems, and Infections in People With Inflammatory Bowel Disease

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Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=12

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        "id": "NCT04652102-84eb655c",
        "title": "CVnCoV 12 μg Vaccine vs Placebo: Number of Participants Who Experienced a Fatal SAE",
        "summary": "11 of 19787 against 12 of 19753; risk difference -0.0 points, 95% interval -0.1 to 0.0; NCT04652102, A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older",
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      },
      {
        "id": "NCT04652102-deaths",
        "title": "CVnCoV 12 μg Vaccine vs Placebo: deaths from any cause",
        "summary": "17 of 19787 against 14 of 19753; risk difference 0.0 points, 95% interval -0.0 to 0.1; NCT04652102, A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older",
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trial-comparisons-2026-03-23-0.1.0Next page

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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