ConductScience.org, home

85,013 comparisons from ClinicalTrials.gov.

85,013 comparisons

Most participants first33,758 with no events in either group come last3,041 to 3,060 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Bronchopulmonary Dysplasia (BPD)8 of 1,208

14 of 1,200

-0.5 points

-1.4 to 0.3

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: 5-min Apgar Score68 of 1,208

80 of 1,200

-1.0 points

-3.0 to 0.9

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Superimposed Gestational Hypertension132 of 1,208

156 of 1,200

-2.1 points

-4.7 to 0.5

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Bradycardia31 of 1,208

35 of 1,200

-0.4 points

-1.7 to 1.0

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Necrotizing Enterocolitis (NEC)2 of 1,208

2 of 1,200

-0.0 points

-0.5 to 0.5

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Cesarean Delivery592 of 1,208

582 of 1,200

0.5 points

-3.5 to 4.5

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Respiratory Distress Syndrome (RDS)149 of 1,208

171 of 1,200

-1.9 points

-4.6 to 0.8

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Intubation/Ventilation298 of 1,208

303 of 1,200

-0.6 points

-4.0 to 2.9

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Composite of Maternal Death or Severe Cardiovascular Morbidity25 of 1,208

33 of 1,200

-0.7 points

-2.0 to 0.6

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Blood Transfusion46 of 1,208

53 of 1,200

-0.6 points

-2.2 to 1.0

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Preterm Birth and Indicated Preterm Birth (<37 Weeks)332 of 1,208

377 of 1,200

-3.9 points

-7.6 to -0.3

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Hyperbilirubinemia266 of 1,208

283 of 1,200

-1.6 points

-4.9 to 1.8

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Severe Hypertension436 of 1,208

531 of 1,200

-8.2 points

-12.0 to -4.2

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: deaths from any cause42 of 1,208

52 of 1,200

-0.9 points

-2.4 to 0.7

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Severe Maternal Hypertension + Components of the Primary Composite Endpoint529 of 1,208

631 of 1,200

-8.8 points

-12.7 to -4.8

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Intraventricular Hemorrhage (IVH)11 of 1,208

17 of 1,200

-0.5 points

-1.4 to 0.4

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: NICU Admission368 of 1,208

402 of 1,200

-3.0 points

-6.8 to 0.7

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Sepsis21 of 1,208

34 of 1,200

-1.1 points

-2.3 to 0.1

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Composite of Severe Neonatal Morbidities24 of 1,208

31 of 1,200

-0.6 points

-1.8 to 0.6

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Hypotension7 of 1,208

16 of 1,200

-0.8 points

-1.6 to 0.0

2,408NCT02299414

Chronic Hypertension and Pregnancy (CHAP) Project

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

No key needed

Code

Show the call in
curl "https://conductscience.org/api/comparisons/v1?page=153"

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=153

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT02299414-2cbb56b8",
        "title": "Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: Bronchopulmonary Dysplasia (BPD)",
        "summary": "8 of 1208 against 14 of 1200; risk difference -0.5 points, 95% interval -1.4 to 0.3; NCT02299414, Chronic Hypertension and Pregnancy (CHAP) Project",
        "record": "/library/comparisons/NCT02299414-2cbb56b8",
        "nct_id": "NCT02299414",
        "kind": "outcome",
        "participants": 2408,
        "risk_difference": {
          "value": -0.0050441501103752765,
          "lower": -0.013518579581555692,
          "upper": 0.002891643525337076
        },
        "group_1": "8 of 1,208",
        "group_2": "14 of 1,200",
        "difference": "-0.5 points",
        "interval": "-1.4 to 0.3",
        "trial_title": "Chronic Hypertension and Pregnancy (CHAP) Project"
      },
      {
        "id": "NCT02299414-2e1e4647",
        "title": "Anti-hypertensive Therapy to Goal <140/90 mmHg vs No Anti-hypertensive Unless BP is Severe (≥160/105 mmHg: 5-min Apgar Score",
        "summary": "68 of 1208 against 80 of 1200; risk difference -1.0 points, 95% interval -3.0 to 0.9; NCT02299414, Chronic Hypertension and Pregnancy (CHAP) Project",
        "record": "/library/comparisons/NCT02299414-2e1e4647",
        "nct_id": "NCT02299414",
        "kind": "outcome",
        "participants": 2408,
        "risk_difference": {
          "value": -0.010375275938189842,
          "lower": -0.02979601402339531,
          "upper": 0.008919529639733848
        },
        "group_1": "68 of 1,208",
        "group_2": "80 of 1,200",
        "difference": "-1.0 points",
        "interval": "-3.0 to 0.9",
        "trial_title": "Chronic Hypertension and Pregnancy (CHAP) Project"
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "No license stated"
    }
  ],
  "next": "/api/comparisons/v1?page=154",
  "request_id": "kxbhtWJrOIO0rh0K"
}

Ask about these results. The first 10 go in the prompt.

About this data
Holds
85,013 comparisons
From ClinicalTrials.gov. Counted 10 Nov 2026.
Release
23 Mar 2026
trial-comparisons-2026-03-23-0.1.0
Checked
20 of 20 review comparisons traced to ClinicalTrials.gov, and all 510,078 numbers calculated again apart from the builder agree
Access
Open
No account. 60 calls a minute from one address.

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

Genes

NCBI Gene

One gene with its proteins, patents, drugs, trials, grants and papers.

Trials

ClinicalTrials.gov

Search clinical trials by condition, drug, outcome or NCT number, with the results each one posted.

Sequences

Patent publications

Paste a sequence and see the patents that disclose it.

Opens sequences.conductscience.org

For software

Read Trial comparisons from software.

Every answer on this page is also JSON, under /api/comparisons/v1. No key.

GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome

Ask an assistant

  • In FOURIER, how did serious adverse events compare between evolocumab and placebo?
  • Which metformin trials reported deaths, and what was the risk difference?
  • What was the number needed to treat for HELIOS-B's composite outcome?
  • Which placebo-controlled heart failure trials had the most participants?