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85,013 comparisons from ClinicalTrials.gov.
Most participants first33,758 with no events in either group come last3,361 to 3,380 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| Symbicort SMART vs Symbicort+Terbutaline As Needed: serious adverse events | 41 of 1,049 74 of 1,042 | -3.2 points -5.2 to -1.2 | 2,091 | NCT00839800 Study to Investigate the Efficacy of Symbicort® SMART. |
| PF-07321332 300 mg + Ritonavir 100 mg vs Placebo: Number of Participants With Treatment Emergent Adverse Events (TEAEs) | 228 of 1,038 256 of 1,053 | -2.3 points -6.0 to 1.3 | 2,091 | NCT04960202 EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19 |
| PF-07321332 300 mg + Ritonavir 100 mg vs Placebo: deaths from any cause | 0 of 1,038 15 of 1,053 | -1.4 points -2.3 to -0.8 | 2,091 | NCT04960202 EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19 |
| PF-07321332 300 mg + Ritonavir 100 mg vs Placebo: serious adverse events | 19 of 1,038 72 of 1,053 | -5.0 points -6.8 to -3.3 | 2,091 | NCT04960202 EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19 |
| Old Lina vs New Lina: Number of Patients With Abnormalities in Clinical Chemistry: Aspartate Transaminase (AST) | 19 of 1,511 3 of 578 | 0.7 points -0.4 to 1.5 | 2,089 | NCT00736099 Safety and Efficacy of Linagliptin (BI 1356) as Monotherapy or in Combination in Type 2 DM |
| Old Lina vs New Lina: Number of Patients With Abnormalities in Clinical Chemistry: Alanine Transaminase (ALT) | 22 of 1,511 5 of 578 | 0.6 points -0.7 to 1.5 | 2,089 | NCT00736099 Safety and Efficacy of Linagliptin (BI 1356) as Monotherapy or in Combination in Type 2 DM |
| Old Lina vs New Lina: Number of Patients With Abnormalities in Clinical Chemistry: Lactate Dehydrogenase (LDH) | 1 of 1,511 0 of 577 | 0.1 points -0.6 to 0.4 | 2,088 | NCT00736099 Safety and Efficacy of Linagliptin (BI 1356) as Monotherapy or in Combination in Type 2 DM |
| DS-5565 15 mg QD Modal vs DS-5565 15 mg BID Modal: deaths from any cause | 3 of 847 2 of 1,241 | 0.2 points -0.3 to 0.9 | 2,088 | NCT02234583 An Open-Label Extension Study of DS-5565 for 52 Weeks in Pain Associated With Fibromyalgia |
| DS-5565 15 mg QD Modal vs DS-5565 15 mg BID Modal: serious adverse events | 41 of 847 94 of 1,241 | -2.7 points -4.8 to -0.6 | 2,088 | NCT02234583 An Open-Label Extension Study of DS-5565 for 52 Weeks in Pain Associated With Fibromyalgia |
| Intervention vs Usual Care: Percentage of Participants Who Receive Influenza Vaccination by April 30 Each Year | 875 of 1,044 843 of 1,042 | 2.9 points -0.4 to 6.2 | 2,086 | NCT03287830 Flu2Text: Text Message Reminders for 2nd Dose of Influenza Vaccine |
| Intervention vs Usual Care: Percentage of Participants Who Receive a Second Vaccination by Day 42 From the Initial Influenza Vaccination | 651 of 1,044 580 of 1,042 | 6.7 points 2.5 to 10.9 | 2,086 | NCT03287830 Flu2Text: Text Message Reminders for 2nd Dose of Influenza Vaccine |
| Narrow Spectrum Antibiotic vs Non-narrow Spectrum Antibiotic: Experience Side Effects | 341 of 1,360 258 of 725 | -10.5 points -14.7 to -6.4 | 2,085 | NCT02297815 Comparative Effectiveness of Antibiotics for Respiratory Infections |
| PF-07321332 300 mg + Ritonavir 100 mg vs Placebo: Number of Participants With Progression to a Worsening Status in 1 or More Self-reported COVID-19 Associated Symptoms Through Day 28-mITT2 Population | 787 of 1,031 790 of 1,050 | 1.1 points -2.6 to 4.8 | 2,081 | NCT04960202 EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19 |
| With Suicidal Ideation (Including Suicide Attempt) vs Without Suicidal Ideation (Including Suicide Attempt): Risk Factors for Incidence Rate of Treatment Related Adverse Events (TRAEs) of Sertraline: Suicidal Ideation (Including Suicide Attempt) | 73 of 469 182 of 1,608 | 4.2 points 0.8 to 8.1 | 2,077 | NCT00605865 Drug Use Investigation of Jzoloft. |
| Warfarin vs NOACs: Number of Participants With Use of Clopidogrel at Start of OAC Treatment | 37 of 459 133 of 1,617 | -0.2 points -2.8 to 2.9 | 2,076 | NCT04234698 Patient Characteristics, Treatment Patterns And Incidence Of Events (Discontinuation, Persistence, Key Primary Clinical Outcomes) In NVAF Patients Initiating OAC Therapy In Colombia |
| Warfarin vs NOACs: Number of Participants With Treatment Discontinuation | 78 of 459 147 of 1,617 | 7.9 points 4.4 to 11.8 | 2,076 | NCT04234698 Patient Characteristics, Treatment Patterns And Incidence Of Events (Discontinuation, Persistence, Key Primary Clinical Outcomes) In NVAF Patients Initiating OAC Therapy In Colombia |
| Warfarin vs NOACs: Number of Participants With Use of Non-Steroidal Anti-Inflammatory Drugs at Start of OAC Treatment | 18 of 459 50 of 1,617 | 0.8 points -0.9 to 3.1 | 2,076 | NCT04234698 Patient Characteristics, Treatment Patterns And Incidence Of Events (Discontinuation, Persistence, Key Primary Clinical Outcomes) In NVAF Patients Initiating OAC Therapy In Colombia |
| Warfarin vs NOACs: Number of Participants With Gastrointestinal Bleeding | 19 of 459 23 of 1,617 | 2.7 points 1.1 to 5.0 | 2,076 | NCT04234698 Patient Characteristics, Treatment Patterns And Incidence Of Events (Discontinuation, Persistence, Key Primary Clinical Outcomes) In NVAF Patients Initiating OAC Therapy In Colombia |
| Warfarin vs NOACs: Number of Participants With Use of Aspirin at Start OAC Treatment | 191 of 459 660 of 1,617 | 0.8 points -4.2 to 5.9 | 2,076 | NCT04234698 Patient Characteristics, Treatment Patterns And Incidence Of Events (Discontinuation, Persistence, Key Primary Clinical Outcomes) In NVAF Patients Initiating OAC Therapy In Colombia |
| Warfarin vs NOACs: Number of Participants With Stroke | 56 of 459 263 of 1,617 | -4.1 points -7.3 to -0.3 | 2,076 | NCT04234698 Patient Characteristics, Treatment Patterns And Incidence Of Events (Discontinuation, Persistence, Key Primary Clinical Outcomes) In NVAF Patients Initiating OAC Therapy In Colombia |
Code
curl "https://conductscience.org/api/comparisons/v1?page=169"
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=169
{
"data": {
"total": 85013,
"results": [
{
"id": "NCT00839800-sae",
"title": "Symbicort SMART vs Symbicort+Terbutaline As Needed: serious adverse events",
"summary": "41 of 1049 against 74 of 1042; risk difference -3.2 points, 95% interval -5.2 to -1.2; NCT00839800, Study to Investigate the Efficacy of Symbicort® SMART.",
"record": "/library/comparisons/NCT00839800-sae",
"nct_id": "NCT00839800",
"kind": "serious-adverse-events",
"participants": 2091,
"risk_difference": {
"value": -0.03193243176482858,
"lower": -0.0519202544611162,
"upper": -0.01242725397395452
},
"group_1": "41 of 1,049",
"group_2": "74 of 1,042",
"difference": "-3.2 points",
"interval": "-5.2 to -1.2",
"trial_title": "Study to Investigate the Efficacy of Symbicort® SMART."
},
{
"id": "NCT04960202-2ca8d32f",
"title": "PF-07321332 300 mg + Ritonavir 100 mg vs Placebo: Number of Participants With Treatment Emergent Adverse Events (TEAEs)",
"summary": "228 of 1038 against 256 of 1053; risk difference -2.3 points, 95% interval -6.0 to 1.3; NCT04960202, EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19",
"record": "/library/comparisons/NCT04960202-2ca8d32f",
"nct_id": "NCT04960202",
"kind": "outcome",
"participants": 2091,
"risk_difference": {
"value": -0.023461730590825014,
"lower": -0.05953172444220046,
"upper": 0.012710387234683367
},
"group_1": "228 of 1,038",
"group_2": "256 of 1,053",
"difference": "-2.3 points",
"interval": "-6.0 to 1.3",
"trial_title": "EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19"
}
],
"no_events": 33758,
"columns": [
{
"key": "title",
"label": "Comparison"
},
{
"key": "group_1",
"label": "With the outcome",
"under": "group_2"
},
{
"key": "difference",
"label": "Risk difference, 95% interval",
"under": "interval"
},
{
"key": "participants",
"label": "Participants"
},
{
"key": "nct_id",
"label": "Trial",
"under": "trial_title"
}
],
"order": "Most participants first",
"kinds": {
"all": 85013,
"outcome": 33568,
"serious-adverse-events": 31897,
"deaths": 19548
}
},
"release": "trial-comparisons-2026-03-23-0.1.0",
"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "Freely available. Acknowledgement requested"
},
{
"source": "ClinicalTrials.gov",
"license": "none stated",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "No license stated"
}
],
"next": "/api/comparisons/v1?page=170",
"request_id": "dDa7g8DLVa21FU5L"
}Ask about these results. The first 10 go in the prompt.
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
NCBI Gene
One gene with its proteins, patents, drugs, trials, grants and papers.
ClinicalTrials.gov
Search clinical trials by condition, drug, outcome or NCT number, with the results each one posted.
Patent publications
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Opens sequences.conductscience.org
For software
Every answer on this page is also JSON, under /api/comparisons/v1. No key.
GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome
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