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85,013 comparisons from ClinicalTrials.gov.

85,013 comparisons

Most participants first33,758 with no events in either group come last3,361 to 3,380 of 85,013

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ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Symbicort SMART vs Symbicort+Terbutaline As Needed: serious adverse events41 of 1,049

74 of 1,042

-3.2 points

-5.2 to -1.2

2,091NCT00839800

Study to Investigate the Efficacy of Symbicort® SMART.

PF-07321332 300 mg + Ritonavir 100 mg vs Placebo: Number of Participants With Treatment Emergent Adverse Events (TEAEs)228 of 1,038

256 of 1,053

-2.3 points

-6.0 to 1.3

2,091NCT04960202

EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19

PF-07321332 300 mg + Ritonavir 100 mg vs Placebo: deaths from any cause0 of 1,038

15 of 1,053

-1.4 points

-2.3 to -0.8

2,091NCT04960202

EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19

PF-07321332 300 mg + Ritonavir 100 mg vs Placebo: serious adverse events19 of 1,038

72 of 1,053

-5.0 points

-6.8 to -3.3

2,091NCT04960202

EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19

Old Lina vs New Lina: Number of Patients With Abnormalities in Clinical Chemistry: Aspartate Transaminase (AST)19 of 1,511

3 of 578

0.7 points

-0.4 to 1.5

2,089NCT00736099

Safety and Efficacy of Linagliptin (BI 1356) as Monotherapy or in Combination in Type 2 DM

Old Lina vs New Lina: Number of Patients With Abnormalities in Clinical Chemistry: Alanine Transaminase (ALT)22 of 1,511

5 of 578

0.6 points

-0.7 to 1.5

2,089NCT00736099

Safety and Efficacy of Linagliptin (BI 1356) as Monotherapy or in Combination in Type 2 DM

Old Lina vs New Lina: Number of Patients With Abnormalities in Clinical Chemistry: Lactate Dehydrogenase (LDH)1 of 1,511

0 of 577

0.1 points

-0.6 to 0.4

2,088NCT00736099

Safety and Efficacy of Linagliptin (BI 1356) as Monotherapy or in Combination in Type 2 DM

DS-5565 15 mg QD Modal vs DS-5565 15 mg BID Modal: deaths from any cause3 of 847

2 of 1,241

0.2 points

-0.3 to 0.9

2,088NCT02234583

An Open-Label Extension Study of DS-5565 for 52 Weeks in Pain Associated With Fibromyalgia

DS-5565 15 mg QD Modal vs DS-5565 15 mg BID Modal: serious adverse events41 of 847

94 of 1,241

-2.7 points

-4.8 to -0.6

2,088NCT02234583

An Open-Label Extension Study of DS-5565 for 52 Weeks in Pain Associated With Fibromyalgia

Intervention vs Usual Care: Percentage of Participants Who Receive Influenza Vaccination by April 30 Each Year875 of 1,044

843 of 1,042

2.9 points

-0.4 to 6.2

2,086NCT03287830

Flu2Text: Text Message Reminders for 2nd Dose of Influenza Vaccine

Intervention vs Usual Care: Percentage of Participants Who Receive a Second Vaccination by Day 42 From the Initial Influenza Vaccination651 of 1,044

580 of 1,042

6.7 points

2.5 to 10.9

2,086NCT03287830

Flu2Text: Text Message Reminders for 2nd Dose of Influenza Vaccine

Narrow Spectrum Antibiotic vs Non-narrow Spectrum Antibiotic: Experience Side Effects341 of 1,360

258 of 725

-10.5 points

-14.7 to -6.4

2,085NCT02297815

Comparative Effectiveness of Antibiotics for Respiratory Infections

PF-07321332 300 mg + Ritonavir 100 mg vs Placebo: Number of Participants With Progression to a Worsening Status in 1 or More Self-reported COVID-19 Associated Symptoms Through Day 28-mITT2 Population787 of 1,031

790 of 1,050

1.1 points

-2.6 to 4.8

2,081NCT04960202

EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19

With Suicidal Ideation (Including Suicide Attempt) vs Without Suicidal Ideation (Including Suicide Attempt): Risk Factors for Incidence Rate of Treatment Related Adverse Events (TRAEs) of Sertraline: Suicidal Ideation (Including Suicide Attempt)73 of 469

182 of 1,608

4.2 points

0.8 to 8.1

2,077NCT00605865

Drug Use Investigation of Jzoloft.

Warfarin vs NOACs: Number of Participants With Use of Clopidogrel at Start of OAC Treatment37 of 459

133 of 1,617

-0.2 points

-2.8 to 2.9

2,076NCT04234698

Patient Characteristics, Treatment Patterns And Incidence Of Events (Discontinuation, Persistence, Key Primary Clinical Outcomes) In NVAF Patients Initiating OAC Therapy In Colombia

Warfarin vs NOACs: Number of Participants With Treatment Discontinuation78 of 459

147 of 1,617

7.9 points

4.4 to 11.8

2,076NCT04234698

Patient Characteristics, Treatment Patterns And Incidence Of Events (Discontinuation, Persistence, Key Primary Clinical Outcomes) In NVAF Patients Initiating OAC Therapy In Colombia

Warfarin vs NOACs: Number of Participants With Use of Non-Steroidal Anti-Inflammatory Drugs at Start of OAC Treatment18 of 459

50 of 1,617

0.8 points

-0.9 to 3.1

2,076NCT04234698

Patient Characteristics, Treatment Patterns And Incidence Of Events (Discontinuation, Persistence, Key Primary Clinical Outcomes) In NVAF Patients Initiating OAC Therapy In Colombia

Warfarin vs NOACs: Number of Participants With Gastrointestinal Bleeding19 of 459

23 of 1,617

2.7 points

1.1 to 5.0

2,076NCT04234698

Patient Characteristics, Treatment Patterns And Incidence Of Events (Discontinuation, Persistence, Key Primary Clinical Outcomes) In NVAF Patients Initiating OAC Therapy In Colombia

Warfarin vs NOACs: Number of Participants With Use of Aspirin at Start OAC Treatment191 of 459

660 of 1,617

0.8 points

-4.2 to 5.9

2,076NCT04234698

Patient Characteristics, Treatment Patterns And Incidence Of Events (Discontinuation, Persistence, Key Primary Clinical Outcomes) In NVAF Patients Initiating OAC Therapy In Colombia

Warfarin vs NOACs: Number of Participants With Stroke56 of 459

263 of 1,617

-4.1 points

-7.3 to -0.3

2,076NCT04234698

Patient Characteristics, Treatment Patterns And Incidence Of Events (Discontinuation, Persistence, Key Primary Clinical Outcomes) In NVAF Patients Initiating OAC Therapy In Colombia

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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Code

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curl "https://conductscience.org/api/comparisons/v1?page=169"

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=169

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT00839800-sae",
        "title": "Symbicort SMART vs Symbicort+Terbutaline As Needed: serious adverse events",
        "summary": "41 of 1049 against 74 of 1042; risk difference -3.2 points, 95% interval -5.2 to -1.2; NCT00839800, Study to Investigate the Efficacy of Symbicort® SMART.",
        "record": "/library/comparisons/NCT00839800-sae",
        "nct_id": "NCT00839800",
        "kind": "serious-adverse-events",
        "participants": 2091,
        "risk_difference": {
          "value": -0.03193243176482858,
          "lower": -0.0519202544611162,
          "upper": -0.01242725397395452
        },
        "group_1": "41 of 1,049",
        "group_2": "74 of 1,042",
        "difference": "-3.2 points",
        "interval": "-5.2 to -1.2",
        "trial_title": "Study to Investigate the Efficacy of Symbicort® SMART."
      },
      {
        "id": "NCT04960202-2ca8d32f",
        "title": "PF-07321332 300 mg + Ritonavir 100 mg vs Placebo: Number of Participants With Treatment Emergent Adverse Events (TEAEs)",
        "summary": "228 of 1038 against 256 of 1053; risk difference -2.3 points, 95% interval -6.0 to 1.3; NCT04960202, EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19",
        "record": "/library/comparisons/NCT04960202-2ca8d32f",
        "nct_id": "NCT04960202",
        "kind": "outcome",
        "participants": 2091,
        "risk_difference": {
          "value": -0.023461730590825014,
          "lower": -0.05953172444220046,
          "upper": 0.012710387234683367
        },
        "group_1": "228 of 1,038",
        "group_2": "256 of 1,053",
        "difference": "-2.3 points",
        "interval": "-6.0 to 1.3",
        "trial_title": "EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19"
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "No license stated"
    }
  ],
  "next": "/api/comparisons/v1?page=170",
  "request_id": "dDa7g8DLVa21FU5L"
}

Ask about these results. The first 10 go in the prompt.

About this data
Holds
85,013 comparisons
From ClinicalTrials.gov. Counted 10 Nov 2026.
Release
23 Mar 2026
trial-comparisons-2026-03-23-0.1.0
Checked
20 of 20 review comparisons traced to ClinicalTrials.gov, and all 510,078 numbers calculated again apart from the builder agree
Access
Open
No account. 60 calls a minute from one address.

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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Every answer on this page is also JSON, under /api/comparisons/v1. No key.

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