Genes
NCBI Gene
One gene with its proteins, patents, drugs, trials, grants and papers.
85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.
Most participants first33,758 with no events in either group come last321 to 340 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| AZD1222 vs Placebo: Number of Participants With First Post-intervention Response for SARS-CoV-2 Nucleocapsid Antibodies Post Second Dose of Study Intervention | 156 of 17,662 202 of 8,550 | -1.5 points -1.8 to -1.1 | 26,212 | NCT04516746 Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults |
| AZD1222 vs Placebo: Number of Participants With COVID-19 Severe or Critical Symptomatic Illness Post Second Dose of Study Intervention | 0 of 17,662 8 of 8,550 | -0.1 points -0.2 to -0.0 | 26,212 | NCT04516746 Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults |
| AZD1222 vs Placebo: Number of Participants With COVID-19-Related Emergency Department Visits Post Second Dose of Study Intervention | 1 of 17,662 9 of 8,550 | -0.1 points -0.2 to -0.0 | 26,212 | NCT04516746 Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults |
| ER Niacin/Laropiprant vs Placebo: Major Vascular Event | 1,696 of 12,838 1,758 of 12,835 | -0.5 points -1.3 to 0.3 | 25,673 | NCT00461630 Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE |
| ER Niacin/Laropiprant vs Placebo: Mortality | 798 of 12,838 732 of 12,835 | 0.5 points -0.1 to 1.1 | 25,673 | NCT00461630 Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE |
| ER Niacin/Laropiprant vs Placebo: Major Coronary Events | 668 of 12,838 694 of 12,835 | -0.2 points -0.8 to 0.3 | 25,673 | NCT00461630 Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE |
| ER Niacin/Laropiprant vs Placebo: Stroke | 498 of 12,838 499 of 12,835 | -0.0 points -0.5 to 0.5 | 25,673 | NCT00461630 Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE |
| ER Niacin/Laropiprant vs Placebo: Coronary or Non-coronary Revascularisation | 807 of 12,838 897 of 12,835 | -0.7 points -1.3 to -0.1 | 25,673 | NCT00461630 Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE |
| ER Niacin/Laropiprant vs Placebo: serious adverse events | 7,137 of 12,838 6,762 of 12,835 | 2.9 points 1.7 to 4.1 | 25,673 | NCT00461630 Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE |
| General Maternal Population (Facility Level) vs General Neonate Population (Facility Level): serious adverse events | 328 of 14,286 260 of 11,063 | -0.1 points -0.4 to 0.3 | 25,349 | NCT03529214 An Evaluation of the Team Birth Project |
| Group 1: Ad26.RSV.preF and RSV preF Protein vs Group 2: Placebo: deaths from any cause | 105 of 16,709 61 of 8,367 | -0.1 points -0.3 to 0.1 | 25,076 | NCT04908683 A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older |
| Group 1: Ad26.RSV.preF and RSV preF Protein vs Group 2: Placebo: serious adverse events | 842 of 16,709 457 of 8,367 | -0.4 points -1.0 to 0.2 | 25,076 | NCT04908683 A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older |
| CVnCoV 12 μg Vaccine vs Placebo: Number of Participants Who Experienced a First Episode of Virologically-confirmed (RT-PCR Positive) Moderate to Severe Case of COVID-19 | 12 of 12,851 37 of 12,211 | -0.2 points -0.3 to -0.1 | 25,062 | NCT04652102 A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older |
| CVnCoV 12 μg Vaccine vs Placebo: Number of Participants Who Experienced a First Episode of Virologically-confirmed {Reverse Transcription Polymerase Chain Reaction (RT-PCR) Positive} Case of COVID-19 of Any Severity | 83 of 12,851 145 of 12,211 | -0.5 points -0.8 to -0.3 | 25,062 | NCT04652102 A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older |
| CVnCoV 12 μg Vaccine vs Placebo: Number of Participants Who Experienced a First Episode of Virologically-confirmed (RT-PCR Positive) Severe Case of COVID-19 | 4 of 12,851 10 of 12,211 | -0.1 points -0.1 to 0.0 | 25,062 | NCT04652102 A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older |
| CVnCoV 12 μg Vaccine vs Placebo: Number of Participants Who Experienced a First Episode of Virologically-confirmed (RT-PCR Positive) Case of COVID-19 of Any Severity Due to Infection With Wild Type and Alpha SARS-CoV-2 Strains in SARS-CoV-2 Naïve Participants | 29 of 12,851 56 of 12,211 | -0.2 points -0.4 to -0.1 | 25,062 | NCT04652102 A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older |
| Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With First Occurrence of Molecularly Confirmed Moderate to Severe/Critical COVID-19 With Onset at Least 28 Days After the First Day 1 Vaccination | 52 of 12,632 161 of 12,402 | -0.9 points -1.1 to -0.7 | 25,034 | NCT04614948 A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults |
| Portal Self-Report vs IVR Self-Report: Intervention Patients With Self-reported Influenza Vaccinations Documented in Electronic Health Record (EHR) | 1,527 of 10,000 6,774 of 15,000 | -29.9 points -30.9 to -28.8 | 25,000 | NCT02266277 System Alignment for VaccinE Delivery (SAVED): Improving Rates of Influenza and Pneumococcal Vaccination Through Patient Outreach, Improved Medical Record Accuracy and Targeted Physician Alerts |
| RSVPreF3 Group vs Placebo Group: Number of Participants With First Episode of RT-PCR Confirmed LRTD Caused by Human Metapneumovirus (hMPV) up to the End of Season 1 Following a Single Dose of the RSVPreF3 OA Vaccine | 53 of 12,469 65 of 12,503 | -0.1 points -0.3 to 0.1 | 24,972 | NCT04886596 Efficacy Study of GSK's Investigational Respiratory Syncytial Virus (RSV) Vaccine in Adults Aged 60 Years and Above |
| RSVPreF3 Group vs Placebo Group: Number of Participants With First Episode of RT-PCR Confirmed RSV A and/or B Associated Lower Respiratory Tract Disease (LRTD) During the First Season Following a Single Dose of the RSVPreF3 OA Vaccine | 7 of 12,466 40 of 12,494 | -0.3 points -0.4 to -0.2 | 24,960 | NCT04886596 Efficacy Study of GSK's Investigational Respiratory Syncytial Virus (RSV) Vaccine in Adults Aged 60 Years and Above |
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=17
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"id": "NCT04516746-c0657a71",
"title": "AZD1222 vs Placebo: Number of Participants With First Post-intervention Response for SARS-CoV-2 Nucleocapsid Antibodies Post Second Dose of Study Intervention",
"summary": "156 of 17662 against 202 of 8550; risk difference -1.5 points, 95% interval -1.8 to -1.1; NCT04516746, Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults",
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{
"id": "NCT04516746-e9c9fa82",
"title": "AZD1222 vs Placebo: Number of Participants With COVID-19 Severe or Critical Symptomatic Illness Post Second Dose of Study Intervention",
"summary": "0 of 17662 against 8 of 8550; risk difference -0.1 points, 95% interval -0.2 to -0.0; NCT04516746, Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults",
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}ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
NCBI Gene
One gene with its proteins, patents, drugs, trials, grants and papers.
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Patent publications
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For software
Every answer on this page is also JSON, under /api/comparisons/v1. No key.
GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome
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