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85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.

85,013 comparisons

Most participants first33,758 with no events in either group come last321 to 340 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
AZD1222 vs Placebo: Number of Participants With First Post-intervention Response for SARS-CoV-2 Nucleocapsid Antibodies Post Second Dose of Study Intervention156 of 17,662

202 of 8,550

-1.5 points

-1.8 to -1.1

26,212NCT04516746

Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults

AZD1222 vs Placebo: Number of Participants With COVID-19 Severe or Critical Symptomatic Illness Post Second Dose of Study Intervention0 of 17,662

8 of 8,550

-0.1 points

-0.2 to -0.0

26,212NCT04516746

Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults

AZD1222 vs Placebo: Number of Participants With COVID-19-Related Emergency Department Visits Post Second Dose of Study Intervention1 of 17,662

9 of 8,550

-0.1 points

-0.2 to -0.0

26,212NCT04516746

Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults

ER Niacin/Laropiprant vs Placebo: Major Vascular Event1,696 of 12,838

1,758 of 12,835

-0.5 points

-1.3 to 0.3

25,673NCT00461630

Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE

ER Niacin/Laropiprant vs Placebo: Mortality798 of 12,838

732 of 12,835

0.5 points

-0.1 to 1.1

25,673NCT00461630

Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE

ER Niacin/Laropiprant vs Placebo: Major Coronary Events668 of 12,838

694 of 12,835

-0.2 points

-0.8 to 0.3

25,673NCT00461630

Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE

ER Niacin/Laropiprant vs Placebo: Stroke498 of 12,838

499 of 12,835

-0.0 points

-0.5 to 0.5

25,673NCT00461630

Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE

ER Niacin/Laropiprant vs Placebo: Coronary or Non-coronary Revascularisation807 of 12,838

897 of 12,835

-0.7 points

-1.3 to -0.1

25,673NCT00461630

Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE

ER Niacin/Laropiprant vs Placebo: serious adverse events7,137 of 12,838

6,762 of 12,835

2.9 points

1.7 to 4.1

25,673NCT00461630

Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE

General Maternal Population (Facility Level) vs General Neonate Population (Facility Level): serious adverse events328 of 14,286

260 of 11,063

-0.1 points

-0.4 to 0.3

25,349NCT03529214

An Evaluation of the Team Birth Project

Group 1: Ad26.RSV.preF and RSV preF Protein vs Group 2: Placebo: deaths from any cause105 of 16,709

61 of 8,367

-0.1 points

-0.3 to 0.1

25,076NCT04908683

A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older

Group 1: Ad26.RSV.preF and RSV preF Protein vs Group 2: Placebo: serious adverse events842 of 16,709

457 of 8,367

-0.4 points

-1.0 to 0.2

25,076NCT04908683

A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older

CVnCoV 12 μg Vaccine vs Placebo: Number of Participants Who Experienced a First Episode of Virologically-confirmed (RT-PCR Positive) Moderate to Severe Case of COVID-1912 of 12,851

37 of 12,211

-0.2 points

-0.3 to -0.1

25,062NCT04652102

A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older

CVnCoV 12 μg Vaccine vs Placebo: Number of Participants Who Experienced a First Episode of Virologically-confirmed {Reverse Transcription Polymerase Chain Reaction (RT-PCR) Positive} Case of COVID-19 of Any Severity83 of 12,851

145 of 12,211

-0.5 points

-0.8 to -0.3

25,062NCT04652102

A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older

CVnCoV 12 μg Vaccine vs Placebo: Number of Participants Who Experienced a First Episode of Virologically-confirmed (RT-PCR Positive) Severe Case of COVID-194 of 12,851

10 of 12,211

-0.1 points

-0.1 to 0.0

25,062NCT04652102

A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older

CVnCoV 12 μg Vaccine vs Placebo: Number of Participants Who Experienced a First Episode of Virologically-confirmed (RT-PCR Positive) Case of COVID-19 of Any Severity Due to Infection With Wild Type and Alpha SARS-CoV-2 Strains in SARS-CoV-2 Naïve Participants29 of 12,851

56 of 12,211

-0.2 points

-0.4 to -0.1

25,062NCT04652102

A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older

Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With First Occurrence of Molecularly Confirmed Moderate to Severe/Critical COVID-19 With Onset at Least 28 Days After the First Day 1 Vaccination52 of 12,632

161 of 12,402

-0.9 points

-1.1 to -0.7

25,034NCT04614948

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults

Portal Self-Report vs IVR Self-Report: Intervention Patients With Self-reported Influenza Vaccinations Documented in Electronic Health Record (EHR)1,527 of 10,000

6,774 of 15,000

-29.9 points

-30.9 to -28.8

25,000NCT02266277

System Alignment for VaccinE Delivery (SAVED): Improving Rates of Influenza and Pneumococcal Vaccination Through Patient Outreach, Improved Medical Record Accuracy and Targeted Physician Alerts

RSVPreF3 Group vs Placebo Group: Number of Participants With First Episode of RT-PCR Confirmed LRTD Caused by Human Metapneumovirus (hMPV) up to the End of Season 1 Following a Single Dose of the RSVPreF3 OA Vaccine53 of 12,469

65 of 12,503

-0.1 points

-0.3 to 0.1

24,972NCT04886596

Efficacy Study of GSK's Investigational Respiratory Syncytial Virus (RSV) Vaccine in Adults Aged 60 Years and Above

RSVPreF3 Group vs Placebo Group: Number of Participants With First Episode of RT-PCR Confirmed RSV A and/or B Associated Lower Respiratory Tract Disease (LRTD) During the First Season Following a Single Dose of the RSVPreF3 OA Vaccine7 of 12,466

40 of 12,494

-0.3 points

-0.4 to -0.2

24,960NCT04886596

Efficacy Study of GSK's Investigational Respiratory Syncytial Virus (RSV) Vaccine in Adults Aged 60 Years and Above

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Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=17

{
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      {
        "id": "NCT04516746-c0657a71",
        "title": "AZD1222 vs Placebo: Number of Participants With First Post-intervention Response for SARS-CoV-2 Nucleocapsid Antibodies Post Second Dose of Study Intervention",
        "summary": "156 of 17662 against 202 of 8550; risk difference -1.5 points, 95% interval -1.8 to -1.1; NCT04516746, Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults",
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      {
        "id": "NCT04516746-e9c9fa82",
        "title": "AZD1222 vs Placebo: Number of Participants With COVID-19 Severe or Critical Symptomatic Illness Post Second Dose of Study Intervention",
        "summary": "0 of 17662 against 8 of 8550; risk difference -0.1 points, 95% interval -0.2 to -0.0; NCT04516746, Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults",
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trial-comparisons-2026-03-23-0.1.0Next page

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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