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85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.

85,013 comparisons

Most participants first33,758 with no events in either group come last801 to 820 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With First Occurrence of Molecularly Confirmed COVID-19 Defined by the US FDA Harmonized Case Definition With Onset at Least 14 Days After the Second Vaccination12 of 6,024

52 of 5,615

-0.7 points

-1.0 to -0.5

11,639NCT04614948

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults

Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With First Occurrence of SARS-CoV-2 Infection (Serologically and/or Molecularly Confirmed) With Onset at Least 14 Days After the Second Vaccination60 of 6,024

113 of 5,615

-1.0 points

-1.5 to -0.6

11,639NCT04614948

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults

Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With First Occurrence of Molecularly Confirmed Moderate to Severe/Critical COVID-19 in Seronegative Participants With Onset at Least 14 Days After the Second Vaccination14 of 6,024

52 of 5,615

-0.7 points

-1.0 to -0.4

11,639NCT04614948

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults

Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With Burden of Disease (BOD) Based on First Occurrence of Molecularly Confirmed Symptomatic COVID-19 With Onset at Least 14 Days After the Second Vaccination14 of 6,024

53 of 5,615

-0.7 points

-1.0 to -0.4

11,639NCT04614948

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults

Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With First Occurrence of Molecularly Confirmed Mild COVID-19 With Onset at Least 14 Days After the Second Vaccination0 of 6,024

1 of 5,615

-0.0 points

-0.1 to 0.0

11,639NCT04614948

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults

Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With Asymptomatic Infection Detected By Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) With Onset at Least 14 Days After the Second Vaccination40 of 6,024

56 of 5,615

-0.3 points

-0.7 to -0.0

11,639NCT04614948

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults

Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With First Occurrence of COVID-19 Requiring Medical Intervention With Onset at Least 14 Days After the Second Vaccination0 of 6,024

5 of 5,615

-0.1 points

-0.2 to -0.0

11,639NCT04614948

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults

Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With Serologic Conversion Between Day 71 up to Unblinding Visit Using an Enzyme-linked Immunosorbent Assay (ELISA)32 of 6,024

45 of 5,615

-0.3 points

-0.6 to 0.0

11,639NCT04614948

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults

Intervention Arm vs Placebo Arm: Maternal Outcome 5 - Incidence of Late Abortion23 of 5,819

30 of 5,808

-0.1 points

-0.4 to 0.1

11,627NCT02409680

Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)

Intervention Arm vs Placebo Arm: Fetal Outcome 4 - Incidence of Fetal Loss303 of 5,818

353 of 5,807

-0.9 points

-1.7 to -0.0

11,625NCT02409680

Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)

Implementation Facilitation Period vs Pre-Implementation Period: Percentage of Patients With OUD Who Experienced a Fatal Opioid-related or Other Drug Overdose During Implementation5 of 6,289

6 of 5,325

-0.0 points

-0.2 to 0.1

11,614NCT04178551

Consortium to Disseminate and Understand Implementation of Opioid Use Disorder Treatment

Implementation Facilitation Period vs Pre-Implementation Period: Percentage of Patients With OUD Who Experienced Opioid-related or Other Drug Overdose During Implementation272 of 6,289

188 of 5,325

0.8 points

0.1 to 1.5

11,614NCT04178551

Consortium to Disseminate and Understand Implementation of Opioid Use Disorder Treatment

Prioritized Clinical Decision Support vs Usual Care: serious adverse events253 of 6,392

151 of 5,159

1.0 points

0.4 to 1.7

11,551NCT01420016

Prioritized Clinical Decision Support (CDS) to Reduce Cardiovascular Risk

Pre-pandemic vs Pandemic: Private2,084 of 8,615

1,356 of 2,930

-22.1 points

-24.1 to -20.1

11,545NCT05532891

Bariatric Surgery and COVID-19

Pre-pandemic vs Pandemic: Revisions746 of 8,615

316 of 2,930

-2.1 points

-3.4 to -0.9

11,545NCT05532891

Bariatric Surgery and COVID-19

Pre-pandemic vs Pandemic: deaths from any cause0 of 8,615

1 of 2,930

-0.0 points

-0.2 to 0.0

11,545NCT05532891

Bariatric Surgery and COVID-19

Intervention Arm vs Placebo Arm: Fetal Outcome 6 - Incidence of All Stillbirth141 of 5,780

166 of 5,764

-0.4 points

-1.0 to 0.1

11,544NCT02409680

Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)

Intervention Arm vs Placebo Arm: Incidence of Preterm Birth668 of 5,780

754 of 5,764

-1.5 points

-2.7 to -0.3

11,544NCT02409680

Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)

Intervention Arm vs Placebo Arm: Maternal Outcome 7 - Incidence of Preterm, Preeclampsia8 of 5,780

21 of 5,764

-0.2 points

-0.4 to -0.0

11,544NCT02409680

Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)

Intervention Arm vs Placebo Arm: Incidence of Hypertensive Disorders of Pregnancy352 of 5,780

325 of 5,764

0.5 points

-0.4 to 1.3

11,544NCT02409680

Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=41

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT04614948-009cba48",
        "title": "Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With First Occurrence of Molecularly Confirmed COVID-19 Defined by the US FDA Harmonized Case Definition With Onset at Least 14 Days After the Second Vaccination",
        "summary": "12 of 6024 against 52 of 5615; risk difference -0.7 points, 95% interval -1.0 to -0.5; NCT04614948, A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults",
        "record": "/library/comparisons/NCT04614948-009cba48",
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          "upper": -0.004620653636096584
        },
        "group_1": "12 of 6,024",
        "group_2": "52 of 5,615",
        "difference": "-0.7 points",
        "interval": "-1.0 to -0.5",
        "trial_title": "A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults"
      },
      {
        "id": "NCT04614948-221d2d82",
        "title": "Double Blind Phase: Ad26.COV2.S vs Double Blind Phase: Placebo: Double Blind Phase: Number of Participants With First Occurrence of SARS-CoV-2 Infection (Serologically and/or Molecularly Confirmed) With Onset at Least 14 Days After the Second Vaccination",
        "summary": "60 of 6024 against 113 of 5615; risk difference -1.0 points, 95% interval -1.5 to -0.6; NCT04614948, A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults",
        "record": "/library/comparisons/NCT04614948-221d2d82",
        "nct_id": "NCT04614948",
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        "group_1": "60 of 6,024",
        "group_2": "113 of 5,615",
        "difference": "-1.0 points",
        "interval": "-1.5 to -0.6",
        "trial_title": "A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults"
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      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
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      "short": "Freely available. Acknowledgement requested"
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      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
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trial-comparisons-2026-03-23-0.1.0Next page

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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