Genes
NCBI Gene
One gene with its proteins, patents, drugs, trials, grants and papers.
85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.
Most participants first33,758 with no events in either group come last921 to 940 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| Pemafibrate vs Placebo: serious adverse events | 1,715 of 5,264 1,663 of 5,274 | 1.0 points -0.7 to 2.8 | 10,538 | NCT03071692 Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT) |
| Pemafibrate vs Placebo: Number of Participants With Occurrence of Any Component of the Primary Endpoint or All-Cause Mortality | 830 of 5,240 806 of 5,257 | 0.5 points -0.9 to 1.9 | 10,497 | NCT03071692 Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT) |
| Pemafibrate vs Placebo: Number of Participants With First Occurrence of Cardiovascular Death | 145 of 5,240 139 of 5,257 | 0.1 points -0.5 to 0.7 | 10,497 | NCT03071692 Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT) |
| Pemafibrate vs Placebo: Number of Participants With First Occurrence of Any Component of the Primary Endpoint or Hospitalization for Heart Failure | 670 of 5,240 645 of 5,257 | 0.5 points -0.8 to 1.8 | 10,497 | NCT03071692 Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT) |
| Pemafibrate vs Placebo: Number of Participants With First Occurrence of the 4-component Composite Secondary Endpoint (Nonfatal MI, Nonfatal Ischemic Stroke, Hospitalization for Unstable Angina Requiring Unplanned Coronary Revascularization, or CV Death) | 447 of 5,240 427 of 5,257 | 0.4 points -0.7 to 1.5 | 10,497 | NCT03071692 Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT) |
| Pemafibrate vs Placebo: Number of Participants With First Occurrence of Nonfatal Ischemic Stroke | 96 of 5,240 106 of 5,257 | -0.2 points -0.7 to 0.3 | 10,497 | NCT03071692 Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT) |
| Pemafibrate vs Placebo: Number of Participants With First Occurrence of Nonfatal Myocardial Infarction | 210 of 5,240 182 of 5,257 | 0.5 points -0.2 to 1.3 | 10,497 | NCT03071692 Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT) |
| Pemafibrate vs Placebo: Number of Participants With First Occurrence of 4-component Composite Primary Endpoint (Nonfatal MI, Nonfatal Ischemic Stroke, Coronary Revascularization, or CV Death) | 590 of 5,240 570 of 5,257 | 0.4 points -0.8 to 1.6 | 10,497 | NCT03071692 Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT) |
| Pemafibrate vs Placebo: Number of Participants With First Occurrence of Coronary Revascularization | 340 of 5,240 347 of 5,257 | -0.1 points -1.1 to 0.8 | 10,497 | NCT03071692 Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT) |
| Pemafibrate vs Placebo: Number of Participants With First Occurrence of the 3-component Composite Endpoint (Nonfatal Myocardial Infarction, Nonfatal Ischemic Stroke, or Cardiovascular Death) | 396 of 5,240 386 of 5,257 | 0.2 points -0.8 to 1.2 | 10,497 | NCT03071692 Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT) |
| Pemafibrate vs Placebo: Number of Participants With First Occurrence of Any New or Worsening Peripheral Artery Disease (PAD) | 138 of 5,240 159 of 5,257 | -0.4 points -1.0 to 0.2 | 10,497 | NCT03071692 Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT) |
| 0.9% Sodium Chloride vs Balanced Crystalloids: Major Adverse Kidney Event Within 30 Days | 551 of 5,214 524 of 5,207 | 0.5 points -0.7 to 1.7 | 10,421 | NCT02547779 Isotonic Solutions and Major Adverse Renal Events Trial in the Non-Medical Intensive Care Unit (SMART-SURG) |
| 0.9% Sodium Chloride vs Balanced Crystalloids: deaths from any cause | 408 of 5,214 400 of 5,207 | 0.1 points -0.9 to 1.2 | 10,421 | NCT02547779 Isotonic Solutions and Major Adverse Renal Events Trial in the Non-Medical Intensive Care Unit (SMART-SURG) |
| 0.9% Sodium Chloride vs Balanced Crystalloids: 30-day In-hospital Mortality | 408 of 5,214 400 of 5,207 | 0.1 points -0.9 to 1.2 | 10,421 | NCT02547779 Isotonic Solutions and Major Adverse Renal Events Trial in the Non-Medical Intensive Care Unit (SMART-SURG) |
| Part A (Open-label): Study Group 1, Analysis Group 1 (AG1) vs Part A (Open-label): Study Group 2, Analysis Group 2-1 (AG2-1): Part A: Number of Participants With a First Occurrence of COVE-defined COVID-19 Starting 1 Day After Month 0 Dose Until Month 6 Dose in FAS Cohort Between Analysis Group 1 (AG1) and Analysis Group 2-1 (AG2-1 | 30 of 2,476 40 of 7,941 | 0.7 points 0.3 to 1.2 | 10,417 | NCT05168813 Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern |
| Part A (Open-label): Study Group 1, Analysis Group 1 (AG1) vs Part A (Open-label): Study Group 2, Analysis Group 2-1 (AG2-1): Part A: Number of Participants With a First Occurrence of CDC-defined COVID-19 Starting 1 Day After Month 0 Dose Until Month 6 Dose in FAS Cohort Between Analysis Group 1 (AG1) and Analysis Group 2-1 (AG2-1) | 76 of 2,476 151 of 7,941 | 1.2 points 0.5 to 2.0 | 10,417 | NCT05168813 Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern |
| Part A (Open-label): Study Group 1, Analysis Group 1 (AG1) vs Part A (Open-label): Study Group 2, Analysis Group 2-1 (AG2-1): Part A: Number of Participants With a First Occurrence of COVE-based Severe COVID-19 Starting 1 Day After Month 0 Dose Until Month 6 Dose in FAS Between Analysis Group 1 (AG1) and Analysis Group 2-1 (AG2-1) | 5 of 2,476 4 of 7,941 | 0.2 points 0.0 to 0.4 | 10,417 | NCT05168813 Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern |
| aQIV (≥6 to <72 Months) vs TIV/QIV (≥6 to <72 Months): serious adverse events | 234 of 5,243 230 of 5,161 | 0.0 points -0.8 to 0.8 | 10,404 | NCT01964989 Clinical Study to Evaluate the Safety, Immunogenicity and Efficacy of Investigational Flu Vaccine Compared to Approved Flu Vaccine in Children. |
| CYD Dengue Vaccine Group vs Placebo Group: deaths from any cause | 10 of 6,848 4 of 3,424 | 0.0 points -0.2 to 0.2 | 10,272 | NCT01373281 Study of a Novel Tetravalent Dengue Vaccine in Healthy Children Aged 2 to 14 Years in Asia |
| CYD Dengue Vaccine Group vs Placebo Group: serious adverse events | 947 of 6,848 552 of 3,424 | -2.3 points -3.8 to -0.8 | 10,272 | NCT01373281 Study of a Novel Tetravalent Dengue Vaccine in Healthy Children Aged 2 to 14 Years in Asia |
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=47
{
"data": {
"total": 85013,
"results": [
{
"id": "NCT03071692-sae",
"title": "Pemafibrate vs Placebo: serious adverse events",
"summary": "1715 of 5264 against 1663 of 5274; risk difference 1.0 points, 95% interval -0.7 to 2.8; NCT03071692, Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)",
"record": "/library/comparisons/NCT03071692-sae",
"nct_id": "NCT03071692",
"kind": "serious-adverse-events",
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"risk_difference": {
"value": 0.01047743244660676,
"lower": -0.007342160015153355,
"upper": 0.028288351194034684
},
"group_1": "1,715 of 5,264",
"group_2": "1,663 of 5,274",
"difference": "1.0 points",
"interval": "-0.7 to 2.8",
"trial_title": "Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)"
},
{
"id": "NCT03071692-09832b7d",
"title": "Pemafibrate vs Placebo: Number of Participants With Occurrence of Any Component of the Primary Endpoint or All-Cause Mortality",
"summary": "830 of 5240 against 806 of 5257; risk difference 0.5 points, 95% interval -0.9 to 1.9; NCT03071692, Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)",
"record": "/library/comparisons/NCT03071692-09832b7d",
"nct_id": "NCT03071692",
"kind": "outcome",
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"upper": 0.01895975940028344
},
"group_1": "830 of 5,240",
"group_2": "806 of 5,257",
"difference": "0.5 points",
"interval": "-0.9 to 1.9",
"trial_title": "Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)"
}
],
"no_events": 33758,
"columns": [
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"deaths": 19548
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},
"release": "trial-comparisons-2026-03-23-0.1.0",
"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "Freely available. Acknowledgement requested"
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{
"source": "ClinicalTrials.gov",
"license": "none stated",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "None stated"
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],
"next": "/api/comparisons/v1?page=48",
"request_id": "jh6IwxPLAQZbtR8d"
}ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
NCBI Gene
One gene with its proteins, patents, drugs, trials, grants and papers.
ClinicalTrials.gov
Search clinical trials by condition, drug, outcome or NCT number, with the results each one posted.
Patent publications
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For invited accounts.
Opens sequences.conductscience.org
For software
Every answer on this page is also JSON, under /api/comparisons/v1. No key.
GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome
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