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85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.

85,013 comparisons

Most participants first33,758 with no events in either group come last921 to 940 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Pemafibrate vs Placebo: serious adverse events1,715 of 5,264

1,663 of 5,274

1.0 points

-0.7 to 2.8

10,538NCT03071692

Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

Pemafibrate vs Placebo: Number of Participants With Occurrence of Any Component of the Primary Endpoint or All-Cause Mortality830 of 5,240

806 of 5,257

0.5 points

-0.9 to 1.9

10,497NCT03071692

Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

Pemafibrate vs Placebo: Number of Participants With First Occurrence of Cardiovascular Death145 of 5,240

139 of 5,257

0.1 points

-0.5 to 0.7

10,497NCT03071692

Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

Pemafibrate vs Placebo: Number of Participants With First Occurrence of Any Component of the Primary Endpoint or Hospitalization for Heart Failure670 of 5,240

645 of 5,257

0.5 points

-0.8 to 1.8

10,497NCT03071692

Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

Pemafibrate vs Placebo: Number of Participants With First Occurrence of the 4-component Composite Secondary Endpoint (Nonfatal MI, Nonfatal Ischemic Stroke, Hospitalization for Unstable Angina Requiring Unplanned Coronary Revascularization, or CV Death)447 of 5,240

427 of 5,257

0.4 points

-0.7 to 1.5

10,497NCT03071692

Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

Pemafibrate vs Placebo: Number of Participants With First Occurrence of Nonfatal Ischemic Stroke96 of 5,240

106 of 5,257

-0.2 points

-0.7 to 0.3

10,497NCT03071692

Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

Pemafibrate vs Placebo: Number of Participants With First Occurrence of Nonfatal Myocardial Infarction210 of 5,240

182 of 5,257

0.5 points

-0.2 to 1.3

10,497NCT03071692

Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

Pemafibrate vs Placebo: Number of Participants With First Occurrence of 4-component Composite Primary Endpoint (Nonfatal MI, Nonfatal Ischemic Stroke, Coronary Revascularization, or CV Death)590 of 5,240

570 of 5,257

0.4 points

-0.8 to 1.6

10,497NCT03071692

Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

Pemafibrate vs Placebo: Number of Participants With First Occurrence of Coronary Revascularization340 of 5,240

347 of 5,257

-0.1 points

-1.1 to 0.8

10,497NCT03071692

Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

Pemafibrate vs Placebo: Number of Participants With First Occurrence of the 3-component Composite Endpoint (Nonfatal Myocardial Infarction, Nonfatal Ischemic Stroke, or Cardiovascular Death)396 of 5,240

386 of 5,257

0.2 points

-0.8 to 1.2

10,497NCT03071692

Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

Pemafibrate vs Placebo: Number of Participants With First Occurrence of Any New or Worsening Peripheral Artery Disease (PAD)138 of 5,240

159 of 5,257

-0.4 points

-1.0 to 0.2

10,497NCT03071692

Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

0.9% Sodium Chloride vs Balanced Crystalloids: Major Adverse Kidney Event Within 30 Days551 of 5,214

524 of 5,207

0.5 points

-0.7 to 1.7

10,421NCT02547779

Isotonic Solutions and Major Adverse Renal Events Trial in the Non-Medical Intensive Care Unit (SMART-SURG)

0.9% Sodium Chloride vs Balanced Crystalloids: deaths from any cause408 of 5,214

400 of 5,207

0.1 points

-0.9 to 1.2

10,421NCT02547779

Isotonic Solutions and Major Adverse Renal Events Trial in the Non-Medical Intensive Care Unit (SMART-SURG)

0.9% Sodium Chloride vs Balanced Crystalloids: 30-day In-hospital Mortality408 of 5,214

400 of 5,207

0.1 points

-0.9 to 1.2

10,421NCT02547779

Isotonic Solutions and Major Adverse Renal Events Trial in the Non-Medical Intensive Care Unit (SMART-SURG)

Part A (Open-label): Study Group 1, Analysis Group 1 (AG1) vs Part A (Open-label): Study Group 2, Analysis Group 2-1 (AG2-1): Part A: Number of Participants With a First Occurrence of COVE-defined COVID-19 Starting 1 Day After Month 0 Dose Until Month 6 Dose in FAS Cohort Between Analysis Group 1 (AG1) and Analysis Group 2-1 (AG2-130 of 2,476

40 of 7,941

0.7 points

0.3 to 1.2

10,417NCT05168813

Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern

Part A (Open-label): Study Group 1, Analysis Group 1 (AG1) vs Part A (Open-label): Study Group 2, Analysis Group 2-1 (AG2-1): Part A: Number of Participants With a First Occurrence of CDC-defined COVID-19 Starting 1 Day After Month 0 Dose Until Month 6 Dose in FAS Cohort Between Analysis Group 1 (AG1) and Analysis Group 2-1 (AG2-1)76 of 2,476

151 of 7,941

1.2 points

0.5 to 2.0

10,417NCT05168813

Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern

Part A (Open-label): Study Group 1, Analysis Group 1 (AG1) vs Part A (Open-label): Study Group 2, Analysis Group 2-1 (AG2-1): Part A: Number of Participants With a First Occurrence of COVE-based Severe COVID-19 Starting 1 Day After Month 0 Dose Until Month 6 Dose in FAS Between Analysis Group 1 (AG1) and Analysis Group 2-1 (AG2-1)5 of 2,476

4 of 7,941

0.2 points

0.0 to 0.4

10,417NCT05168813

Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern

aQIV (≥6 to <72 Months) vs TIV/QIV (≥6 to <72 Months): serious adverse events234 of 5,243

230 of 5,161

0.0 points

-0.8 to 0.8

10,404NCT01964989

Clinical Study to Evaluate the Safety, Immunogenicity and Efficacy of Investigational Flu Vaccine Compared to Approved Flu Vaccine in Children.

CYD Dengue Vaccine Group vs Placebo Group: deaths from any cause10 of 6,848

4 of 3,424

0.0 points

-0.2 to 0.2

10,272NCT01373281

Study of a Novel Tetravalent Dengue Vaccine in Healthy Children Aged 2 to 14 Years in Asia

CYD Dengue Vaccine Group vs Placebo Group: serious adverse events947 of 6,848

552 of 3,424

-2.3 points

-3.8 to -0.8

10,272NCT01373281

Study of a Novel Tetravalent Dengue Vaccine in Healthy Children Aged 2 to 14 Years in Asia

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=47

{
  "data": {
    "total": 85013,
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      {
        "id": "NCT03071692-sae",
        "title": "Pemafibrate vs Placebo: serious adverse events",
        "summary": "1715 of 5264 against 1663 of 5274; risk difference 1.0 points, 95% interval -0.7 to 2.8; NCT03071692, Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)",
        "record": "/library/comparisons/NCT03071692-sae",
        "nct_id": "NCT03071692",
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          "upper": 0.028288351194034684
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        "group_2": "1,663 of 5,274",
        "difference": "1.0 points",
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        "trial_title": "Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)"
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      {
        "id": "NCT03071692-09832b7d",
        "title": "Pemafibrate vs Placebo: Number of Participants With Occurrence of Any Component of the Primary Endpoint or All-Cause Mortality",
        "summary": "830 of 5240 against 806 of 5257; risk difference 0.5 points, 95% interval -0.9 to 1.9; NCT03071692, Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)",
        "record": "/library/comparisons/NCT03071692-09832b7d",
        "nct_id": "NCT03071692",
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        "group_2": "806 of 5,257",
        "difference": "0.5 points",
        "interval": "-0.9 to 1.9",
        "trial_title": "Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)"
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      "serious-adverse-events": 31897,
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  "terms": [
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      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
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      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
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      "source": "ClinicalTrials.gov",
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      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
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trial-comparisons-2026-03-23-0.1.0Next page

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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