Genes
NCBI Gene
One gene with its proteins, patents, drugs, trials, grants and papers.
85,013 comparisons from ClinicalTrials.gov.
Most participants first33,758 with no events in either group come last1,861 to 1,880 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| Sodium Bicarbonate vs Saline: Number of Participants With Serious, Adverse, Patient-Centered Events, Including Death, Need for Acute Dialysis, or Persistent Decline in Kidney Function, Comparing Intravenous Sodium Bicarbonate With Intravenous Sodium Chloride. | 111 of 2,393 116 of 2,379 | -0.2 points -1.5 to 1.0 | 4,772 | NCT01467466 Prevention of Serious Adverse Events Following Angiography |
| Pertuzumab + Trastuzumab + Chemotherapy vs Placebo + Trastuzumab + Chemotherapy: serious adverse events | 792 of 2,364 686 of 2,405 | 5.0 points 2.4 to 7.6 | 4,769 | NCT01358877 A Study of Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer |
| Interactive Two-way SMS Dialogue vs No SMS Control: Cord Care | 1,123 of 2,374 1,104 of 2,378 | 0.9 points -2.0 to 3.7 | 4,752 | NCT04598165 Mobile WACh NEO: Mobile Solutions for Neonatal Health and Maternal Support |
| Colchicine vs Colchicine Placebo: Heart Failure Hospitalization | 25 of 2,366 18 of 2,379 | 0.3 points -0.3 to 0.9 | 4,745 | NCT02551094 Colchicine Cardiovascular Outcomes Trial (COLCOT) |
| Colchicine vs Colchicine Placebo: Coronary Revascularization | 132 of 2,366 164 of 2,379 | -1.3 points -2.7 to 0.1 | 4,745 | NCT02551094 Colchicine Cardiovascular Outcomes Trial (COLCOT) |
| Colchicine vs Colchicine Placebo: First Event of Cardiovascular Death, Resuscitated Cardiac Arrest, Acute Myocardial Infarction, Stroke, or Urgent Hospitalization for Angina Requiring Coronary Revascularization | 131 of 2,366 170 of 2,379 | -1.6 points -3.0 to -0.2 | 4,745 | NCT02551094 Colchicine Cardiovascular Outcomes Trial (COLCOT) |
| Colchicine vs Colchicine Placebo: Cardiovascular Death | 20 of 2,366 24 of 2,379 | -0.2 points -0.7 to 0.4 | 4,745 | NCT02551094 Colchicine Cardiovascular Outcomes Trial (COLCOT) |
| Colchicine vs Colchicine Placebo: Death (Total Mortality) | 43 of 2,366 44 of 2,379 | -0.0 points -0.8 to 0.7 | 4,745 | NCT02551094 Colchicine Cardiovascular Outcomes Trial (COLCOT) |
| Colchicine vs Colchicine Placebo: Atrial Fibrillation | 36 of 2,366 40 of 2,379 | -0.2 points -0.9 to 0.6 | 4,745 | NCT02551094 Colchicine Cardiovascular Outcomes Trial (COLCOT) |
| Colchicine vs Colchicine Placebo: Stroke | 5 of 2,366 19 of 2,379 | -0.6 points -1.0 to -0.2 | 4,745 | NCT02551094 Colchicine Cardiovascular Outcomes Trial (COLCOT) |
| Colchicine vs Colchicine Placebo: Resuscitated Cardiac Arrest | 5 of 2,366 6 of 2,379 | -0.0 points -0.4 to 0.3 | 4,745 | NCT02551094 Colchicine Cardiovascular Outcomes Trial (COLCOT) |
| Colchicine vs Colchicine Placebo: Myocardial Infarction | 89 of 2,366 98 of 2,379 | -0.4 points -1.5 to 0.8 | 4,745 | NCT02551094 Colchicine Cardiovascular Outcomes Trial (COLCOT) |
| Colchicine vs Colchicine Placebo: Urgent Hospitalization for Angina Requiring Coronary Revascularization | 25 of 2,366 50 of 2,379 | -1.0 points -1.8 to -0.3 | 4,745 | NCT02551094 Colchicine Cardiovascular Outcomes Trial (COLCOT) |
| Colchicine vs Colchicine Placebo: First Event of Cardiovascular Death, Resuscitated Cardiac Arrest, Acute MI or Stroke. | 111 of 2,366 130 of 2,379 | -0.8 points -2.0 to 0.5 | 4,745 | NCT02551094 Colchicine Cardiovascular Outcomes Trial (COLCOT) |
| Colchicine vs Colchicine Placebo: First Event of Deep Venous Thrombosis or Pulmonary Embolus | 10 of 2,366 7 of 2,379 | 0.1 points -0.2 to 0.5 | 4,745 | NCT02551094 Colchicine Cardiovascular Outcomes Trial (COLCOT) |
| Dapa 10 mg vs Placebo: Subjects Included in the Composite Endpoint of ≥50% Sustained Decline in eGFR, ESRD or Renal Death. | 28 of 2,373 39 of 2,371 | -0.5 points -1.2 to 0.2 | 4,744 | NCT03036124 Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure |
| Dapa 10 mg vs Placebo: Subjects Included in the Endpoint of All-cause Mortality. | 276 of 2,373 329 of 2,371 | -2.2 points -4.1 to -0.3 | 4,744 | NCT03036124 Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure |
| Dapa 10 mg vs Placebo: Subjects Included in the Composite Endpoint of CV Death or Hospitalization Due to Heart Failure. | 382 of 2,373 495 of 2,371 | -4.8 points -7.0 to -2.6 | 4,744 | NCT03036124 Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure |
| Dapa 10 mg vs Placebo: Subjects Included in the Composite Endpoint of CV Death, Hospitalization Due to Heart Failure or Urgent Visit Due to Heart Failure. | 386 of 2,373 502 of 2,371 | -4.9 points -7.1 to -2.7 | 4,744 | NCT03036124 Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure |
| MACE Events at 1 Year Subject Whose FFRCT Was >0.80 vs MACE Events at 1 Year. Patients With at Least One FFRCT Value ≤ 0.80: Percentage of Major Adverse Coronary Events (MACE) at 1 Year | 12 of 1,592 43 of 3,145 | -0.6 points -1.2 to 0.0 | 4,737 | NCT02499679 Assessing Diagnostic Value of Non-invasive FFRCT in Coronary Care |
Code
curl "https://conductscience.org/api/comparisons/v1?page=94"
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=94
{
"data": {
"total": 85013,
"results": [
{
"id": "NCT01467466-f1c480e5",
"title": "Sodium Bicarbonate vs Saline: Number of Participants With Serious, Adverse, Patient-Centered Events, Including Death, Need for Acute Dialysis, or Persistent Decline in Kidney Function, Comparing Intravenous Sodium Bicarbonate With Intravenous Sodium Chloride.",
"summary": "111 of 2393 against 116 of 2379; risk difference -0.2 points, 95% interval -1.5 to 1.0; NCT01467466, Prevention of Serious Adverse Events Following Angiography",
"record": "/library/comparisons/NCT01467466-f1c480e5",
"nct_id": "NCT01467466",
"kind": "outcome",
"participants": 4772,
"risk_difference": {
"value": -0.002374692755790636,
"lower": -0.01454520879722701,
"upper": 0.009768088710277532
},
"group_1": "111 of 2,393",
"group_2": "116 of 2,379",
"difference": "-0.2 points",
"interval": "-1.5 to 1.0",
"trial_title": "Prevention of Serious Adverse Events Following Angiography"
},
{
"id": "NCT01358877-sae",
"title": "Pertuzumab + Trastuzumab + Chemotherapy vs Placebo + Trastuzumab + Chemotherapy: serious adverse events",
"summary": "792 of 2364 against 686 of 2405; risk difference 5.0 points, 95% interval 2.4 to 7.6; NCT01358877, A Study of Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer",
"record": "/library/comparisons/NCT01358877-sae",
"nct_id": "NCT01358877",
"kind": "serious-adverse-events",
"participants": 4769,
"risk_difference": {
"value": 0.04978629547157465,
"lower": 0.023535280250455357,
"upper": 0.07595430297801115
},
"group_1": "792 of 2,364",
"group_2": "686 of 2,405",
"difference": "5.0 points",
"interval": "2.4 to 7.6",
"trial_title": "A Study of Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer"
}
],
"no_events": 33758,
"columns": [
{
"key": "title",
"label": "Comparison"
},
{
"key": "group_1",
"label": "With the outcome",
"under": "group_2"
},
{
"key": "difference",
"label": "Risk difference, 95% interval",
"under": "interval"
},
{
"key": "participants",
"label": "Participants"
},
{
"key": "nct_id",
"label": "Trial",
"under": "trial_title"
}
],
"order": "Most participants first",
"kinds": {
"all": 85013,
"outcome": 33568,
"serious-adverse-events": 31897,
"deaths": 19548
}
},
"release": "trial-comparisons-2026-03-23-0.1.0",
"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "Freely available. Acknowledgement requested"
},
{
"source": "ClinicalTrials.gov",
"license": "none stated",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "No license stated"
}
],
"next": "/api/comparisons/v1?page=95",
"request_id": "8SKxvKEjyoSc6fpI"
}Ask about these results. The first 10 go in the prompt.
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
NCBI Gene
One gene with its proteins, patents, drugs, trials, grants and papers.
ClinicalTrials.gov
Search clinical trials by condition, drug, outcome or NCT number, with the results each one posted.
Patent publications
Paste a sequence and see the patents that disclose it.
Opens sequences.conductscience.org
For software
Every answer on this page is also JSON, under /api/comparisons/v1. No key.
GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome
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