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85,013 comparisons from ClinicalTrials.gov.

85,013 comparisons

Most participants first33,758 with no events in either group come last1,861 to 1,880 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Sodium Bicarbonate vs Saline: Number of Participants With Serious, Adverse, Patient-Centered Events, Including Death, Need for Acute Dialysis, or Persistent Decline in Kidney Function, Comparing Intravenous Sodium Bicarbonate With Intravenous Sodium Chloride.111 of 2,393

116 of 2,379

-0.2 points

-1.5 to 1.0

4,772NCT01467466

Prevention of Serious Adverse Events Following Angiography

Pertuzumab + Trastuzumab + Chemotherapy vs Placebo + Trastuzumab + Chemotherapy: serious adverse events792 of 2,364

686 of 2,405

5.0 points

2.4 to 7.6

4,769NCT01358877

A Study of Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer

Interactive Two-way SMS Dialogue vs No SMS Control: Cord Care1,123 of 2,374

1,104 of 2,378

0.9 points

-2.0 to 3.7

4,752NCT04598165

Mobile WACh NEO: Mobile Solutions for Neonatal Health and Maternal Support

Colchicine vs Colchicine Placebo: Heart Failure Hospitalization25 of 2,366

18 of 2,379

0.3 points

-0.3 to 0.9

4,745NCT02551094

Colchicine Cardiovascular Outcomes Trial (COLCOT)

Colchicine vs Colchicine Placebo: Coronary Revascularization132 of 2,366

164 of 2,379

-1.3 points

-2.7 to 0.1

4,745NCT02551094

Colchicine Cardiovascular Outcomes Trial (COLCOT)

Colchicine vs Colchicine Placebo: First Event of Cardiovascular Death, Resuscitated Cardiac Arrest, Acute Myocardial Infarction, Stroke, or Urgent Hospitalization for Angina Requiring Coronary Revascularization131 of 2,366

170 of 2,379

-1.6 points

-3.0 to -0.2

4,745NCT02551094

Colchicine Cardiovascular Outcomes Trial (COLCOT)

Colchicine vs Colchicine Placebo: Cardiovascular Death20 of 2,366

24 of 2,379

-0.2 points

-0.7 to 0.4

4,745NCT02551094

Colchicine Cardiovascular Outcomes Trial (COLCOT)

Colchicine vs Colchicine Placebo: Death (Total Mortality)43 of 2,366

44 of 2,379

-0.0 points

-0.8 to 0.7

4,745NCT02551094

Colchicine Cardiovascular Outcomes Trial (COLCOT)

Colchicine vs Colchicine Placebo: Atrial Fibrillation36 of 2,366

40 of 2,379

-0.2 points

-0.9 to 0.6

4,745NCT02551094

Colchicine Cardiovascular Outcomes Trial (COLCOT)

Colchicine vs Colchicine Placebo: Stroke5 of 2,366

19 of 2,379

-0.6 points

-1.0 to -0.2

4,745NCT02551094

Colchicine Cardiovascular Outcomes Trial (COLCOT)

Colchicine vs Colchicine Placebo: Resuscitated Cardiac Arrest5 of 2,366

6 of 2,379

-0.0 points

-0.4 to 0.3

4,745NCT02551094

Colchicine Cardiovascular Outcomes Trial (COLCOT)

Colchicine vs Colchicine Placebo: Myocardial Infarction89 of 2,366

98 of 2,379

-0.4 points

-1.5 to 0.8

4,745NCT02551094

Colchicine Cardiovascular Outcomes Trial (COLCOT)

Colchicine vs Colchicine Placebo: Urgent Hospitalization for Angina Requiring Coronary Revascularization25 of 2,366

50 of 2,379

-1.0 points

-1.8 to -0.3

4,745NCT02551094

Colchicine Cardiovascular Outcomes Trial (COLCOT)

Colchicine vs Colchicine Placebo: First Event of Cardiovascular Death, Resuscitated Cardiac Arrest, Acute MI or Stroke.111 of 2,366

130 of 2,379

-0.8 points

-2.0 to 0.5

4,745NCT02551094

Colchicine Cardiovascular Outcomes Trial (COLCOT)

Colchicine vs Colchicine Placebo: First Event of Deep Venous Thrombosis or Pulmonary Embolus10 of 2,366

7 of 2,379

0.1 points

-0.2 to 0.5

4,745NCT02551094

Colchicine Cardiovascular Outcomes Trial (COLCOT)

Dapa 10 mg vs Placebo: Subjects Included in the Composite Endpoint of ≥50% Sustained Decline in eGFR, ESRD or Renal Death.28 of 2,373

39 of 2,371

-0.5 points

-1.2 to 0.2

4,744NCT03036124

Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure

Dapa 10 mg vs Placebo: Subjects Included in the Endpoint of All-cause Mortality.276 of 2,373

329 of 2,371

-2.2 points

-4.1 to -0.3

4,744NCT03036124

Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure

Dapa 10 mg vs Placebo: Subjects Included in the Composite Endpoint of CV Death or Hospitalization Due to Heart Failure.382 of 2,373

495 of 2,371

-4.8 points

-7.0 to -2.6

4,744NCT03036124

Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure

Dapa 10 mg vs Placebo: Subjects Included in the Composite Endpoint of CV Death, Hospitalization Due to Heart Failure or Urgent Visit Due to Heart Failure.386 of 2,373

502 of 2,371

-4.9 points

-7.1 to -2.7

4,744NCT03036124

Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure

MACE Events at 1 Year Subject Whose FFRCT Was >0.80 vs MACE Events at 1 Year. Patients With at Least One FFRCT Value ≤ 0.80: Percentage of Major Adverse Coronary Events (MACE) at 1 Year12 of 1,592

43 of 3,145

-0.6 points

-1.2 to 0.0

4,737NCT02499679

Assessing Diagnostic Value of Non-invasive FFRCT in Coronary Care

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

No key needed

Code

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curl "https://conductscience.org/api/comparisons/v1?page=94"

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=94

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT01467466-f1c480e5",
        "title": "Sodium Bicarbonate vs Saline: Number of Participants With Serious, Adverse, Patient-Centered Events, Including Death, Need for Acute Dialysis, or Persistent Decline in Kidney Function, Comparing Intravenous Sodium Bicarbonate With Intravenous Sodium Chloride.",
        "summary": "111 of 2393 against 116 of 2379; risk difference -0.2 points, 95% interval -1.5 to 1.0; NCT01467466, Prevention of Serious Adverse Events Following Angiography",
        "record": "/library/comparisons/NCT01467466-f1c480e5",
        "nct_id": "NCT01467466",
        "kind": "outcome",
        "participants": 4772,
        "risk_difference": {
          "value": -0.002374692755790636,
          "lower": -0.01454520879722701,
          "upper": 0.009768088710277532
        },
        "group_1": "111 of 2,393",
        "group_2": "116 of 2,379",
        "difference": "-0.2 points",
        "interval": "-1.5 to 1.0",
        "trial_title": "Prevention of Serious Adverse Events Following Angiography"
      },
      {
        "id": "NCT01358877-sae",
        "title": "Pertuzumab + Trastuzumab + Chemotherapy vs Placebo + Trastuzumab + Chemotherapy: serious adverse events",
        "summary": "792 of 2364 against 686 of 2405; risk difference 5.0 points, 95% interval 2.4 to 7.6; NCT01358877, A Study of Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer",
        "record": "/library/comparisons/NCT01358877-sae",
        "nct_id": "NCT01358877",
        "kind": "serious-adverse-events",
        "participants": 4769,
        "risk_difference": {
          "value": 0.04978629547157465,
          "lower": 0.023535280250455357,
          "upper": 0.07595430297801115
        },
        "group_1": "792 of 2,364",
        "group_2": "686 of 2,405",
        "difference": "5.0 points",
        "interval": "2.4 to 7.6",
        "trial_title": "A Study of Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer"
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "No license stated"
    }
  ],
  "next": "/api/comparisons/v1?page=95",
  "request_id": "8SKxvKEjyoSc6fpI"
}

Ask about these results. The first 10 go in the prompt.

About this data
Holds
85,013 comparisons
From ClinicalTrials.gov. Counted 10 Nov 2026.
Release
23 Mar 2026
trial-comparisons-2026-03-23-0.1.0
Checked
20 of 20 review comparisons traced to ClinicalTrials.gov, and all 510,078 numbers calculated again apart from the builder agree
Access
Open
No account. 60 calls a minute from one address.

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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Every answer on this page is also JSON, under /api/comparisons/v1. No key.

GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome

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