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Disease · HP_0000708

Trials15

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 1 more is not shown, since the checks do not confirm it.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT00584701Pharmacogenomics in Autism TreatmentPhase 2/3492012-07-24AutismRISPERIDONEIts record names the diseaseClinicalTrials.gov
NCT04292457Namsos Anaesthesia Children Outcome StudyNot applicable761Emergence DeliriumPROPOFOL, SEVOFLURANEIts record names the diseaseClinicalTrials.gov
NCT01021696Pain in Patients With Dementia and Behavioural DisturbancesPhase 2/3352Dementia, Pain, AgitationACETAMINOPHEN, BUPRENORPHINE, MORPHINE, PREGABALINIts record names the diseaseClinicalTrials.gov
NCT00249145A Study of the Effectiveness and Safety of Risperidone in the Treatment of Behavioral Disturbances in Patients With DementiaPhase 3349Dementia, Alzheimer Disease, Dementia, VascularRISPERIDONEIts record names the diseaseClinicalTrials.gov
NCT02956226Cannabinoids for Behavioral Problems in Children With ASDPhase 2150Autistic DisorderCANNABIDIOL, DRONABINOLIts record names the diseaseClinicalTrials.gov
NCT03862950A Trial of Metformin in Individuals With Fragile X Syndrome (Met)Phase 2125
Fragile X Syndrome, Fragile X Mental Retardation Syndrome, Mental Retardation, X-Linked, Genetic Diseases, X-Linked, Trinucleotide Repeat Expansion, Fra(X) Syndrome, Intellectual Disability, FXS, Neurobehavioral Manifestations, Sex Chromosome Disorders
METFORMINOpen Targets' reading of its recordClinicalTrials.gov
NCT03479476A Trial of Metformin in Individuals With Fragile X SyndromePhase 2/3120
Fragile X Syndrome, Fragile X Mental Retardation Syndrome, Mental Retardation, X Linked, Genetic Diseases, X-Linked, Trinucleotide Repeat Expansion, Fra(X) Syndrome, Intellectual Disability, FXS, Neurobehavioral Manifestations, Sex Chromosome Disorders
METFORMINOpen Targets' reading of its recordClinicalTrials.gov
NCT00005014Treatment of Autism in Children and AdolescentsPhase 3101Autistic DisorderRISPERIDONEIts record names the diseaseClinicalTrials.gov
NCT00160147Treatment of Elderly Subjects With Psychosis and Behavioral Disturbances Associated With Dementia of the Alzheimer's TypePhase 360Psychosis and Behavioral Disturbances Associated With Dementia of the Alzheimer's TypeBIFEPRUNOXIts record names the diseaseClinicalTrials.gov
NCT01730209Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis ComplexPhase 2/360Tuberous Sclerosis Complex, TSC Related Cognitive Disability, TSC Related Autism, TSC Related Learning ProblemsEVEROLIMUSIts record names the diseaseClinicalTrials.gov
NCT01608217Delta-THC in DementiaPhase 250Behavioural Disturbances, Pain, Dementia, Alzheimer's Dementia, Vascular DementiaACETAMINOPHEN, DRONABINOLIts record names the diseaseClinicalTrials.gov
NCT02942498Clinical Trial for Asses the Safety and Efficacy of Vitamin C and Vitamin E in Combination Versus Placebo for Treating Cognitive and Behavior Disorder in Children With Fragile X SyndromePhase 334X Fragile SyndromeVITAMIN EOpen Targets' reading of its recordClinicalTrials.gov
NCT05818943Honeycomb: Evaluation of Radiprodil in Children with GRIN-related DisorderPhase 124GRIN-related DisordersRADIPRODILIts record names the diseaseClinicalTrials.gov
NCT00254930A Prospective Study of Risperdal (Risperidone) for the Treatment of Behavioral Disorder Following Psychological Therapy for Challenging Behavior in Learning Disabled ChildrenPhase 319Learning Disorders, Child Behavior DisordersRISPERIDONEOpen Targets' reading of its recordClinicalTrials.gov
NCT00347152Comparison of Immediate vs Gradual Switch to Divalproex in Adults With Intellectual DisabilityNot applicable18EpilepsyDIVALPROEX SODIUMOpen Targets' reading of its recordClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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