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Disease · MONDO_0001347

Comparisons in its trials15

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Part A: Losmapimod 15 Milligrams (mg) vs Part A: Placebo: Part A: Number of Participants With Clinically Significant Changes in Vital Parameters0 of 1300 of 130260NCT05397470Trial comparisons
Part A: Losmapimod 15 Milligrams (mg) vs Part A: Placebo: Part A: Number of Participants With Clinically Significant Changes in Physical Examinations0 of 1300 of 130260NCT05397470Trial comparisons
Part A: Losmapimod 15 Milligrams (mg) vs Part A: Placebo: Part A: Number of Participants With Clinically Significant Changes in Electrocardiogram (ECG) Parameters0 of 1300 of 130260NCT05397470Trial comparisons
Part A: Losmapimod 15 Milligrams (mg) vs Part A: Placebo: Part A: Number of Participants With Clinically Significant Changes in Urinalysis0 of 1300 of 130260NCT05397470Trial comparisons
Part A: Losmapimod 15 Milligrams (mg) vs Part A: Placebo: Part A: Number of Participants With Clinically Significant Changes in Hematology Parameters0 of 1300 of 130260NCT05397470Trial comparisons
Part A: Losmapimod 15 Milligrams (mg) vs Part A: Placebo: Part A: Number of Participants With Clinically Significant Changes in Clinical Chemistry Parameters0 of 1300 of 130260NCT05397470Trial comparisons
Losmapimod 15 Milligrams (mg) Twice Daily (BID) vs Placebo: Number of Participants With Adverse Events of Special Interest (AESIs)0 of 400 of 4080NCT04003974Trial comparisons
Losmapimod 15 Milligrams (mg) Twice Daily (BID) vs Placebo: deaths from any cause0 of 400 of 4080NCT04003974Trial comparisons
Losmapimod 15 Milligrams (mg) Twice Daily (BID) vs Placebo: Number of Participants Who Prematurely Discontinued Study Drug Due to a Treatment Emergent Adverse Event (TEAE)0 of 400 of 4080NCT04003974Trial comparisons
Losmapimod 15 Milligrams (mg) Twice Daily (BID) vs Placebo: serious adverse events2 of 400 of 4080NCT04003974Trial comparisons
Group A - FSHD vs Group B - LGMD2B and FSHD: Number of Participants With Vital Sign Abnormality Resulting in a TEAE0 of 43 of 1418NCT02579239Trial comparisons
Group A - FSHD vs Group B - LGMD2B and FSHD: Number of Participants With a Clinical Laboratory Abnormality Leading to an AE0 of 44 of 1418NCT02579239Trial comparisons
Group A - FSHD vs Group B - LGMD2B and FSHD: Number of Participants With a Clinically Significant Pulmonary Function Event Resulting in a TEAE0 of 40 of 1418NCT02579239Trial comparisons
Group A - FSHD vs Group B - LGMD2B and FSHD: Number of Participants With a Clinically Significant Electrocardiogram (ECG) Abnormality Leading to a TEAE0 of 40 of 1418NCT02579239Trial comparisons
Group A - FSHD vs Group B - LGMD2B and FSHD: serious adverse events0 of 40 of 1418NCT02579239Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0001347/comparisons