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Disease · MONDO_0001673

Trials72

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 8 more are not shown, since the checks do not confirm them.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT00547898Safety and Effectiveness of 3 Doses of Crofelemer Compared to Placebo in the Treatment of HIV Associated DiarrheaPhase 33742020-09-03HIV Associated DiarrheaCROFELEMERIts record names the diseaseClinicalTrials.gov
NCT01142089Study to Evaluate Safety and Efficacy of Rifamycin SV Multi-Matrix System (MMX) for the Treatment of Traveler's Diarrhea (TD)Phase 32642018-04-10Traveler's DiarrheaRIFAMYCIN SODIUMOpen Targets' reading of its recordClinicalTrials.gov
NCT01374490Safety and Tolerability of Crofelemer for HIV-Associated DiarrheaPhase 32502020-08-17HIV Enteropathy, Diarrhea With HIVCROFELEMERIts record names the diseaseClinicalTrials.gov
NCT01718873Optimization of Bevacizumab Scheduling With Chemotherapy for Metastatic Colorectal CancerPhase 32302023-04-12Colorectal CancerBEVACIZUMAB, CAPECITABINE, FLUOROURACIL, OXALIPLATINIts record names the diseaseClinicalTrials.gov
NCT03633344Efficacy of the Administration of Colloidal Silicon Dioxide in Tablet Dosage Form in Patients With Acute DiarrheaPhase 21452019-06-06Diarrhoea;AcuteSILICON DIOXIDEIts record names the diseaseClinicalTrials.gov
NCT00774930An Efficacy and Safety Study of Somatuline Depot (Lanreotide) Injection to Treat Carcinoid SyndromePhase 31152016-02-09Carcinoid SyndromeLANREOTIDEIts record names the diseaseClinicalTrials.gov
NCT04150250Cholera Anti-Secretory Treatment TrialPhase 2472021-03-25CholeraIOWH-032Its record names the diseaseClinicalTrials.gov
NCT01591863Safety, Tolerability, and Pharmacokinetics of Fidaxomicin in Pediatric Subjects With Clostridium Difficile-associated Diarrhea (CDAD)Phase 2382015-03-17Clostridium Difficile-associated DiarrheaFIDAXOMICINOpen Targets' reading, confirmed by NLM's indexing of its papersClinicalTrials.gov
NCT03473561Study to Evaluate the Efficacy and Safety of Racecadotril in Children Aged 3 to 60 Months Suffering From Acute DiarrheaPhase 3312023-11-24Diarrhea, InfantileRACECADOTRILIts record names the diseaseClinicalTrials.gov
NCT02920242A Study Comparing Two Rifaximin Tablets in Patients With Travelers' Diarrhea.Phase 3282019-03-25Travelers' DiarrheaRIFAXIMINOpen Targets' reading of its recordClinicalTrials.gov
NCT03767257A Study of Colesevelam for Lenalidomide-Associated DiarrheaPhase 2252025-10-21Multiple Myeloma, DiarrheaCOLESEVELAMIts record names the diseaseClinicalTrials.gov
NCT00853047Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome Not Managed by Stable-Dose Octreotide TherapyPhase 2232018-12-26Carcinoid SyndromeOCTREOTIDE, TELOTRISTATIts record names the diseaseClinicalTrials.gov
NCT00304356Compassionate Use of Nitazoxanide for the Treatment of Clostridium Difficile InfectionPhase 3222017-12-15Clostridium Enterocolitis, Pseudomembranous ColitisNITAZOXANIDEIts record names the diseaseClinicalTrials.gov
NCT04486326Crofelemer for Functional DiarrheaPhase 4172026-03-10DiarrheaCROFELEMERIts record names the diseaseClinicalTrials.gov
NCT04046328Efficacy, Safety and Tolerability of Enteric-Coated Cholestyramine Capsules for Adult Short Bowel SyndromePhase 2132022-07-19Short Bowel SyndromeCHOLESTYRAMINEIts record names the diseaseClinicalTrials.gov
NCT02991768Budesonide for Mycophenolic Acid-induced Diarrhea in Renal Transplant RecipientsPhase 292024-09-19DiarrheaBUDESONIDEIts record names the diseaseClinicalTrials.gov
NCT01327300Efficacy of Mesalamine in Diarrhea-predominant Irritable Bowel Syndrome (dIBS)Phase 272014-02-12Irritable Bowel SyndromeMESALAMINEIts record names the diseaseClinicalTrials.gov
NCT02619812Manage Diarrhea in Patients With Multiple Myeloma While Receiving Conditioning Chemotherapy for Autologous SCTPhase 242017-06-14Multiple MyelomaCOLESEVELAM HYDROCHLORIDEIts record names the diseaseClinicalTrials.gov
NCT04456517Reduce Crohn's-Associated Diarrhea With Sodium Channel TherapyPhase 242025-02-06Crohn's Disease, Inflammatory Bowel DiseaseRANOLAZINEIts record names the diseaseClinicalTrials.gov
NCT01346059Intracolonic Vancomycin Therapy in Severe C. Diff ColitisNot applicable22017-03-29ColitisVANCOMYCINIts record names the diseaseClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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