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Disease · MONDO_0005029

Comparisons in its trials11

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
PEGASYS vs Hydroxyurea: Number of Participants With Major Cardiovascular Events After Therapy1 of 821 of 86168NCT01259856Trial comparisons
PEGASYS vs Hydroxyurea: deaths from any cause0 of 821 of 86168NCT01259856Trial comparisons
PEGASYS vs Hydroxyurea: serious adverse events14 of 824 of 86168NCT01259856Trial comparisons
SPD422: Safety Analysis Set vs SPD422: Post-marketing Trial Safety Analysis Set: serious adverse events21 of 531 of 3386NCT01467661Trial comparisons
JAK2 Positive Participants vs JAK2 Negative Participants: serious adverse events0 of 230 of 2447NCT01352585Trial comparisons
JAK2 Positive Participants vs JAK2 Negative Participants: Number of Patients With Platelet Count ≤600x10^9/L After 12 Months12 of 1414 of 2135NCT01352585Trial comparisons
JAK2 Positive Participants vs JAK2 Negative Participants: Number of Patients With Platelet Count ≤400x10^9/L After 12 Months7 of 148 of 2135NCT01352585Trial comparisons
Agrylin (Young) vs Agrylin (Elderly): serious adverse events0 of 120 of 1224NCT00413634Trial comparisons
Group A : Ruxolitinib and Anagrelide Placebo vs Group B : Anagrelide and Ruxolitinib Placebo: deaths from any cause0 of 50 of 611NCT03123588Trial comparisons
Group A : Ruxolitinib and Anagrelide Placebo vs Group B : Anagrelide and Ruxolitinib PLacebo: Number of Participants With Treatment Emergent Adverse Events (TEAEs)5 of 54 of 611NCT03123588Trial comparisons
Group A : Ruxolitinib and Anagrelide Placebo vs Group B : Anagrelide and Ruxolitinib Placebo: serious adverse events0 of 51 of 611NCT03123588Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0005029/comparisons