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Disease · MONDO_0005082

Comparisons in its trials26

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Neoadjuvant TAS 2 Months Before and During RT vs Radiation Therapy Alone: serious adverse events33 of 1,00316 of 1,0032,006NCT00002597Trial comparisons
TAS x 8 Weeks vs TAS x 28 Weeks: serious adverse events121 of 747109 of 7351,482NCT00005044Trial comparisons
Arm I: Bicalutamide + Goserelin vs Arm II: Mitoxantrone + Prednisone + Bivalutamid + Goserelin: deaths from any cause85 of 46991 of 460929NCT00004124Trial comparisons
Arm I: Bicalutamide + Goserelin vs Arm II: Mitoxantrone + Prednisone + Bivalutamid + Goserelin: serious adverse events3 of 46911 of 460929NCT00004124Trial comparisons
Treatment Group: Sipuleucel-T vs Control Arm: Active Surveillance: Efficacy of Sipuleucel-T Measured as the Percentage of Subjects Without Histological Reclassification (Gleason Group Upgrade).108 of 35648 of 176532NCT03686683Trial comparisons
Treatment Group: Sipuleucel-T vs Control Arm: Active Surveillance: deaths from any cause10 of 3565 of 176532NCT03686683Trial comparisons
Treatment Group: Sipuleucel-T vs Control Arm: Active Surveillance: serious adverse events74 of 34522 of 176521NCT03686683Trial comparisons
Sipuleucel-T vs APC-Placebo: serious adverse events82 of 33840 of 168506NCT00065442Trial comparisons
Abemaciclib vs Placebo: deaths from any cause81 of 20672 of 187393NCT03706365Trial comparisons
Abemaciclib vs Placebo: serious adverse events89 of 20666 of 185391NCT03706365Trial comparisons
Leuprolide Acetate - Formulation A vs Leuprolide Acetate - Formulation B: serious adverse events31 of 15141 of 159310NCT00626431Trial comparisons
PDR001+LAG525 On-treatment Period vs PDR001+LAG525 Extended Safety Follow-up Period: deaths from any cause9 of 7618 of 76152NCT03365791Trial comparisons
PDR001+LAG525 On-treatment Period vs PDR001+LAG525 Extended Safety Follow-up Period: serious adverse events31 of 764 of 76152NCT03365791Trial comparisons
Arm I vs Arm II: serious adverse events20 of 299 of 2857NCT00527124Trial comparisons
Arm A - Enzalutamide for 3 Months vs Arm B - Enzalutamide for 3 Months + PSA-TRICOM: deaths from any cause0 of 190 of 1938NCT01875250Trial comparisons
Arm A - Enzalutamide for 3 Months vs Arm B - Enzalutamide for 3 Months + PSA-TRICOM: Number of Participants With Serious and Non-serious Adverse Events Assessed by the Common Terminology Criteria for Adverse Events (CTCAE v4.0)
19 of 1919 of 1938NCT01875250Trial comparisons
Arm A - Enzalutamide for 3 Months vs Arm B - Enzalutamide for 3 Months + PSA-TRICOM: serious adverse events0 of 191 of 1938NCT01875250Trial comparisons
Arm I vs Arm II: Safety and Tolerability Assessed Using NCI CTCAE Version 4.00 of 50 of 510NCT01200810Trial comparisons
Arm II - RO4929097 vs Arm I - Placebo: serious adverse events0 of 50 of 510NCT01200810Trial comparisons
Group A- GDC-0449 and Androgen Ablation (LHRHa) vs Group B- Androgren Ablation (LHRHa) Alone: deaths from any cause0 of 40 of 59NCT01163084Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0005082/comparisons