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Disease · MONDO_0005235

Comparisons in its trials11

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Arm A: Active Monitoring (ACTM) vs Arm B: Daratumumab SC: deaths from any cause26 of 19615 of 194390NCT03301220Trial comparisons
Arm A: Active Monitoring (ACTM) vs Arm B: Daratumumab SC: serious adverse events38 of 19656 of 193389NCT03301220Trial comparisons
Siltuximab vs Placebo: deaths from any cause3 of 434 of 4285NCT01484275Trial comparisons
Siltuximab vs Placebo: serious adverse events13 of 4313 of 4285NCT01484275Trial comparisons
Arm I: Thal/ZLD vs Arm II: ZLD: Number of Participants With Severe (Grade 3, 4 or 5) Adverse Events17 of 3513 of 3368NCT00432458Trial comparisons
Arm I: Thal/ZLD vs Arm II: ZLD: Number of Participants With a Confirmed Response (Complete Response [CR], Very Good Partial Response [VGPR] or Partial Response [PR]) on Two Consecutive Evaluations at Least 2 Weeks Apart in the First 12 Months of Treatment
13 of 350 of 3368NCT00432458Trial comparisons
Arm I: Thal/ZLD vs Arm II: ZLD: 12-month Progression-free Survival (PFS)30 of 3518 of 3368NCT00432458Trial comparisons
Arm I: Thal/ZLD vs Arm II: ZLD: serious adverse events3 of 351 of 3368NCT00432458Trial comparisons
Elotuzumab(E) : 10 mg/kg/Dose vs Elotuzumab(E) : 20 mg/kg/Dose: serious adverse events7 of 168 of 1531NCT01441973Trial comparisons
Cohort B (Lenalidomide, Dexamethasone) vs Cohort C (Lenalidomide, Dexamethasone, Pomalidomide): deaths from any cause0 of 50 of 1116NCT05288062Trial comparisons
Cohort B (Lenalidomide, Dexamethasone) vs Cohort C (Lenalidomide, Dexamethasone, Pomalidomide): serious adverse events0 of 52 of 1116NCT05288062Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0005235/comparisons