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Disease · MONDO_0005366

Comparisons in its trials64

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
TDF-TDF vs ADV-TDF: deaths from any cause1 of 2570 of 252509NCT01300234Trial comparisons
TDF-TDF vs ADV-TDF: serious adverse events12 of 25720 of 252509NCT01300234Trial comparisons
Tenofovir vs Peginterferon-alfa 2a and Tenofovir: Number of Participants With Serious Adverse Events11 of 1027 of 99201NCT01369212Trial comparisons
Tenofovir vs Peginterferon-alfa 2a and Tenofovir: Number of Participants With Adverse Events50 of 10260 of 99201NCT01369212Trial comparisons
Tenofovir vs Peginterferon-alfa 2a and Tenofovir: deaths from any cause0 of 1020 of 99201NCT01369212Trial comparisons
Tenofovir vs Peginterferon-alfa 2a and Tenofovir: serious adverse events11 of 1027 of 99201NCT01369212Trial comparisons
Peginterferon Alfa-2a + Entecavir vs Entecavir: serious adverse events6 of 970 of 100197NCT00940485Trial comparisons
Tenofovir vs Peginterferon-alfa 2a and Tenofovir: Number of Participants With HBsAg Seroconversion at Week 1921 of 964 of 92188NCT01369212Trial comparisons
Tenofovir vs Peginterferon-alfa 2a and Tenofovir: Number of Participants With Alanine Transaminase(ALT) Levels <= 38 U/L for Males and <=25 for Females at Week 19258 of 9672 of 91187NCT01369212Trial comparisons
Tenofovir vs Peginterferon-alfa 2a and Tenofovir: Number of Participants With Normal Alanine Transaminase (ALT) Levels at Week 19237 of 9651 of 91187NCT01369212Trial comparisons
Tenofovir vs Peginterferon-alfa 2a and Tenofovir: Number of Participants With HBV DNA<1000 IU/mL at Week 19295 of 9690 of 91187NCT01369212Trial comparisons
Tenofovir vs Peginterferon-alfa 2a and Tenofovir: Number of Participants With HBV DNA<20 IU/mL at Week 19282 of 9687 of 91187NCT01369212Trial comparisons
Tenofovir vs Peginterferon-alfa 2a and Tenofovir: Number of Participants With Normal Alanine Transaminase (ALT) Levels at Week 24038 of 9241 of 89181NCT01369212Trial comparisons
Tenofovir vs Peginterferon-alfa 2a and Tenofovir: Number of Participants With HBV DNA<1000 IU/mL at Week 24066 of 9265 of 89181NCT01369212Trial comparisons
Tenofovir vs Peginterferon-alfa 2a and Tenofovir: Number of Participants With HBV DNA<20 IU/mL at Week 24046 of 9248 of 89181NCT01369212Trial comparisons
ETV (Entecavir) vs PLACEBO: deaths from any cause0 of 1200 of 60180NCT01079806Trial comparisons
ETV (Entecavir) vs PLACEBO: serious adverse events4 of 1209 of 60180NCT01079806Trial comparisons
Tenofovir vs Peginterferon-alfa 2a and Tenofovir: Number of Participants With HBsAg Seroconversion at Week 2402 of 914 of 89180NCT01369212Trial comparisons
TDF 300 mg OD vs ETV 0.5 mg OD: Number of Participants With Virological Breakthrough Through End of the Study2 of 1092 of 56165NCT01480284Trial comparisons
TDF 300 mg OD vs ETV 0.5 mg OD: serious adverse events7 of 1092 of 56165NCT01480284Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

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