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Disease · MONDO_0005487

Comparisons in its trials36

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Lurasidone vs Risperidone: Number of Participants With Adverse Events.395 of 427189 of 202629NCT00641745Trial comparisons
Lurasidone vs Risperidone: serious adverse events46 of 41920 of 202621NCT00641745Trial comparisons
Injectable Risperidone vs Oral Antipsychotic: serious adverse events96 of 18791 of 182369NCT00132314Trial comparisons
Paliperidone Extended-Release (ER) vs Placebo: serious adverse events11 of 2148 of 95309NCT00412373Trial comparisons
Paliperidone Extended-Release (ER) vs Placebo: Participants With Response85 of 21126 of 93304NCT00412373Trial comparisons
Seroquel XR vs Risperidone: serious adverse events4 of 1094 of 107216NCT00640562Trial comparisons
Seroquel XR vs Risperidone: Concomitant Use of Antidepressive Drugs From Baseline to Week 1214 of 10717 of 103210NCT00640562Trial comparisons
Seroquel XR vs Risperidone: Concomitant Use of Antidepressive Drugs From Baseline to Week 1212 of 10711 of 103210NCT00640562Trial comparisons
Varenicline vs Placebo: Number of Participants With 7-day Point Prevalence of Non-smoking at Week 1216 of 842 of 43127NCT00644969Trial comparisons
Varenicline vs Placebo: Number of Participants With 7-day Point Prevalence of Non-smoking at Week 2410 of 841 of 43127NCT00644969Trial comparisons
Varenicline vs Placebo: serious adverse events5 of 844 of 43127NCT00644969Trial comparisons
Varenicline vs Placebo: Number of Participants With Suicidal Behavior and / or Ideation (Yes Response) on the Columbia Suicide Severity Rating Scale (C-SSRS) During the Treatment Phase9 of 824 of 43125NCT00644969Trial comparisons
Cognitive Remediation vs Cognitive Activity Control Group: serious adverse events5 of 567 of 64120NCT01173874Trial comparisons
Varenicline vs Placebo: Number of Participants With Suicidal Behavior or Suicical Ideation (Yes Response ) on the Columbia Suicide-Severity Rating Scale (C-SSRS) During the Post Treatment Phase6 of 700 of 39109NCT00644969Trial comparisons
Arm 1: Pregnenolone vs Arm 2: Placebo: serious adverse events3 of 424 of 4688NCT00728728Trial comparisons
CBSST + Oxytocin vs CBSST + Placebo: serious adverse events1 of 310 of 3162NCT01752712Trial comparisons
Levetiracetam vs Placebo: deaths from any cause0 of 300 of 2757NCT03034356Trial comparisons
Levetiracetam vs Placebo: serious adverse events0 of 300 of 2757NCT03034356Trial comparisons
Omega-3 Fatty Acid vs Placebo: serious adverse events0 of 280 of 2452NCT00167310Trial comparisons
Fingolimod vs Placebo: deaths from any cause0 of 180 of 2240NCT01779700Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0005487/comparisons