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Disease · MONDO_0005556

Comparisons in its trials71

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Belimumab 10 mg/kg vs Placebo: Double-blind Period: Number of Participants With Time to Death or Renal Related Event35 of 22363 of 223446NCT01639339Trial comparisons
Abatacept IV vs Placebo IV: Number of Participants With Abatacept Induced Antibody Response Over Time in the Double-blind Period7 of 2029 of 203405NCT01714817Trial comparisons
Abatacept IV vs Placebo IV: deaths from any cause7 of 2026 of 203405NCT01714817Trial comparisons
Abatacept IV vs Placebo IV: serious adverse events62 of 20258 of 203405NCT01714817Trial comparisons
Voclosporin vs Placebo Oral Capsule: deaths from any cause1 of 1785 of 178356NCT03021499Trial comparisons
Voclosporin vs Placebo Oral Capsule: serious adverse events37 of 17838 of 178356NCT03021499Trial comparisons
Secukinumab 300 mg vs Placebo: deaths from any cause1 of 1371 of 138275NCT04181762Trial comparisons
Secukinumab 300 mg vs Placebo: serious adverse events30 of 13739 of 138275NCT04181762Trial comparisons
Obinutuzumab vs Placebo: Number of Participants With Adverse Events (AEs)126 of 136117 of 132268NCT04221477Trial comparisons
Obinutuzumab vs Placebo: deaths from any cause5 of 1364 of 132268NCT04221477Trial comparisons
Obinutuzumab vs Placebo: serious adverse events44 of 13624 of 132268NCT04221477Trial comparisons
Mycophenolate Mofetil (MMF) vs Azathioprine (AZA): Maintenance Phase: Events Contributing to the Primary Endpoint: Number of Participants With End-stage Renal Disease (ESRD)0 of 1163 of 111227NCT00377637Trial comparisons
Mycophenolate Mofetil vs Azathioprine: Maintenance Phase: Participants With Major Extra-renal Flare7 of 1166 of 111227NCT00377637Trial comparisons
Mycophenolate Mofetil vs Azathioprine: Maintenance Phase: Events Contributing to the Primary Endpoint: Number of Participants With Sustained Doubling of Serum Creatinine1 of 1165 of 111227NCT00377637Trial comparisons
Voclosporin vs Placebo Oral Capsule: deaths from any cause0 of 1163 of 100216NCT03597464Trial comparisons
Voclosporin vs Placebo Oral Capsule: serious adverse events21 of 11623 of 100216NCT03597464Trial comparisons
Abatacept vs Placebo: serious adverse events28 of 6926 of 68137NCT00774852Trial comparisons
Abatacept vs Placebo: Number of Participants Fulfilling the Proteinuria and Prednisone Criteria of a Complete Response22 of 6621 of 68134NCT00774852Trial comparisons
Abatacept vs Placebo: Number of Participants Fulfilling the Proteinuria and Prednisone Criteria of a Partial Response39 of 6642 of 68134NCT00774852Trial comparisons
Abatacept vs Placebo: Number of Participants With Partial Response39 of 6640 of 68134NCT00774852Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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