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Disease · MONDO_0005575

Comparisons in its trials324

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Panitumumab vs Concomitant Administration of Panitumumab and Chemotherapy: serious adverse events614 of 1,254747 of 1,8313,085NCT02089737Trial comparisons
Napabucasin + FOLFIRI ± Bevacizumab vs FOLFIRI ± Bevacizumab: deaths from any cause507 of 624499 of 6291,253NCT02753127Trial comparisons
Napabucasin + FOLFIRI ± Bevacizumab vs FOLFIRI ± Bevacizumab: serious adverse events234 of 622201 of 6101,232NCT02753127Trial comparisons
Aflibercept/FOLFIRI vs Placebo/FOLFIRI: serious adverse events294 of 611198 of 6051,216NCT00561470Trial comparisons
Cetuximab Plus FOLFIRI vs FOLFIRI Alone: Safety - Number of Patients Experiencing Any Adverse Event599 of 600597 of 6021,202NCT00154102Trial comparisons
Cetuximab Plus FOLFIRI vs FOLFIRI Alone: serious adverse events263 of 600204 of 6021,202NCT00154102Trial comparisons
Cetuximab Plus FOLFIRI vs FOLFIRI Alone: Participants With No Residual Tumor After Metastatic Surgery29 of 59910 of 5991,198NCT00154102Trial comparisons
Panitumumab Plus FOLFOX vs FOLFOX Alone: serious adverse events262 of 585198 of 5841,169NCT00364013Trial comparisons
Arm A: FOLFOX or FOLFIRI + Bevacizumab vs Arm B: FOLFOX or FOLFIRI + Cetuximab: serious adverse events98 of 559111 of 5781,137NCT00265850Trial comparisons
FOLFIRI + Ramucirumab vs FOLFIRI + Placebo: serious adverse events198 of 529175 of 5281,057NCT01183780Trial comparisons
Panit. Plus Bevacizumab With Chemotherapy vs Bevacizumab With Chemotherapy: serious adverse events306 of 518188 of 5101,028NCT00115765Trial comparisons
Cetuximab vs Panitumumab: serious adverse events169 of 503151 of 496999NCT01001377Trial comparisons
Cediranib 20 mg vs Placebo: Overall Response Rate254 of 502178 of 358860NCT00399035Trial comparisons
Chemotherapy vs Chemotherapy + Bevacizumab: Participants With Progression Free Survival Event394 of 410386 of 409819NCT00700102Trial comparisons
Group P; mFOLFOX6 + Panitumumab Combination Therapy vs Group B; mFOLFOX6 + Bevacizumab Combination Therapy: Number of Participants With Treatment-emergent Adverse Events (TEAE)402 of 404398 of 407811NCT02394795Trial comparisons
Group P; mFOLFOX6 + Panitumumab Combination Therapy vs Group B; mFOLFOX6 + Bevacizumab Combination Therapy: deaths from any cause14 of 4049 of 407811NCT02394795Trial comparisons
Group P; mFOLFOX6 + Panitumumab Combination Therapy vs Group B; mFOLFOX6 + Bevacizumab Combination Therapy: serious adverse events115 of 40495 of 407811NCT02394795Trial comparisons
Chemotherapy vs Chemotherapy + Bevacizumab: serious adverse events137 of 409130 of 401810NCT00700102Trial comparisons
Group P; mFOLFOX6 + Panitumumab Combination Therapy vs Group B; mFOLFOX6 + Bevacizumab Combination Therapy: Number of Participants Treated With Curative Surgical Resection After Chemotherapy66 of 40044 of 402802NCT02394795Trial comparisons
TAS-102 vs Placebo: deaths from any cause17 of 53330 of 265798NCT01607957Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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