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Disease · MONDO_0005607

Comparisons in its trials16

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
R500 vs Placebo: serious adverse events8 of 795 of 79158NCT01509677Trial comparisons
Tozorakimab vs Placebo: Number of Participants With Abnormal Electrocardiograms (ECGs) Reported as TEAEs1 of 670 of 68135NCT04631016Trial comparisons
Tozorakimab vs Placebo: Number of Participants Experiencing First Chronic Obstructive Pulmonary Disease Composite Exacerbations (COPDCompEx) Event28 of 6736 of 68135NCT04631016Trial comparisons
Tozorakimab vs Placebo: deaths from any cause0 of 670 of 68135NCT04631016Trial comparisons
Tozorakimab vs Placebo: serious adverse events14 of 679 of 68135NCT04631016Trial comparisons
N-Acetylcysteine vs Placebo: deaths from any cause0 of 230 of 2245NCT01739790Trial comparisons
N-Acetylcysteine vs Placebo: serious adverse events3 of 232 of 2245NCT01739790Trial comparisons
Ivacaftor vs Placebo: Safety of Ivacaftor - Number of Participants With Abnormal Serum Chemistry0 of 290 of 1039NCT03085485Trial comparisons
Ivacaftor vs Placebo: Safety of Ivacaftor - Number of Participants With Abnormal Hematology0 of 290 of 1039NCT03085485Trial comparisons
Ivacaftor vs Placebo: deaths from any cause19 of 296 of 1039NCT03085485Trial comparisons
Ivacaftor vs Placebo: Safety of Ivacaftor - Number of Participants With Abnormal ECG (Prolonged QT Intervals)1 of 291 of 1039NCT03085485Trial comparisons
Ivacaftor vs Placebo: serious adverse events6 of 291 of 1039NCT03085485Trial comparisons
Roflumilast vs Placebo: serious adverse events0 of 110 of 1627NCT01572948Trial comparisons
Prednisone vs Placebo: deaths from any cause0 of 120 of 1224NCT03861390Trial comparisons
Prednisone vs Placebo: serious adverse events0 of 120 of 1224NCT03861390Trial comparisons
Tozorakimab vs Placebo: Number of Participants Seropositive for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)6 of 66 of 713NCT04631016Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0005607/comparisons