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Disease · MONDO_0005689

Comparisons in its trials41

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

1 to 20 of 41

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ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Gabapentin 1200mg/Day vs Placebo: serious adverse events0 of 1501 of 150300NCT00974376Trial comparisons
N-acetylcysteine vs Placebo: deaths from any cause0 of 980 of 94192NCT03055377Trial comparisons
N-acetylcysteine vs Placebo: serious adverse events0 of 980 of 94192NCT03055377Trial comparisons
Varenicline vs Placebo: deaths from any cause0 of 900 of 84174NCT03980561Trial comparisons
Varenicline vs Placebo: serious adverse events1 of 900 of 84174NCT03980561Trial comparisons
Quetiapine vs Placebo: deaths from any cause0 of 660 of 64130NCT01697709Trial comparisons
Quetiapine vs Placebo: serious adverse events0 of 660 of 64130NCT01697709Trial comparisons
Lofexidine and Dronabinol vs Placebo: 21 Days of Consecutive Abstinence as Measured by the Time-line Followback.17 of 6118 of 61122NCT01020019Trial comparisons
Lofexidine and Dronabinol vs Placebo: serious adverse events1 of 611 of 61122NCT01020019Trial comparisons
N-Acetylcysteine vs Placebo: deaths from any cause0 of 580 of 58116NCT01005810Trial comparisons
N-Acetylcysteine vs Placebo: serious adverse events0 of 580 of 58116NCT01005810Trial comparisons
Vilazodone vs Placebo: serious adverse events0 of 410 of 3576NCT01574183Trial comparisons
Fluoxetine vs Placebo: serious adverse events0 of 340 of 3670NCT00149643Trial comparisons
Aprepitant: 125mg/Day vs Matched Placebo: serious adverse events0 of 320 of 3870NCT01611948Trial comparisons
PF-04457845 (4mg by Mouth Daily for 4 Weeks) vs Placebo (Sugar Pill, by Mouth Daily for 4 Weeks): deaths from any cause0 of 460 of 2470NCT01618656Trial comparisons
PF-04457845 (4mg by Mouth Daily for 4 Weeks) vs Placebo (Sugar Pill, by Mouth Daily for 4 Weeks): serious adverse events0 of 460 of 2470NCT01618656Trial comparisons
Clonazepam vs Placebo: deaths from any cause0 of 340 of 3468NCT02913924Trial comparisons
Clonazepam vs Placebo: serious adverse events1 of 341 of 3468NCT02913924Trial comparisons
Non-Randomized Participants vs Placebo/Dronabinol: deaths from any cause0 of 370 of 2461NCT00480441Trial comparisons
Non-Randomized Participants vs Placebo/Dronabinol: serious adverse events0 of 370 of 2461NCT00480441Trial comparisons

diseases-2026-09-18-0.1.0

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Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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