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Disease · MONDO_0005920

Comparisons in its trials27

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
PA Group vs AL Group: deaths from any cause0 of 8490 of 4231,272NCT00422084Trial comparisons
PA Group vs AL Group: serious adverse events3 of 8492 of 4231,272NCT00422084Trial comparisons
Pyronaridine - Artesunate vs Mefloquine Plus Artesunate: deaths from any cause0 of 8480 of 4231,271NCT00403260Trial comparisons
Pyronaridine - Artesunate vs Mefloquine Plus Artesunate: serious adverse events6 of 8483 of 4231,271NCT00403260Trial comparisons
Artemether-lumefantrine for 3 Days Plus Primaquine at Hour 24 vs Artemether-lumefantrine for 3 Days Plus Amodiaquine for 3 Days Plus Primaquine at Hour 24: Polymerase Chain Reaction Corrected Efficacy Defined as Adequate Clinical and Parasitological Response (ACPR) by Study Arm
146 of 154151 of 156310NCT03355664Trial comparisons
Artemether-lumefantrine for 3 Days Plus Primaquine at Hour 24 vs Artemether-lumefantrine for 3 Days Plus Amodiaquine for 3 Days Plus Primaquine at Hour 24: Number of Severe Adverse Events by Study Arm2 of 1545 of 156310NCT03355664Trial comparisons
Artemether-lumefantrine for 3 Days Plus Primaquine at Hour 24 vs Artemether-lumefantrine for 3 Days Plus Amodiaquine for 3 Days Plus Primaquine at Hour 24: deaths from any cause0 of 1540 of 156310NCT03355664Trial comparisons
Artemether-lumefantrine for 3 Days Plus Primaquine at Hour 24 vs Artemether-lumefantrine for 3 Days Plus Amodiaquine for 3 Days Plus Primaquine at Hour 24: serious adverse events2 of 1545 of 156310NCT03355664Trial comparisons
Artemether-lumefantrine (Coartem™) + Primaquine vs Chloroquine + Primaquine: deaths from any cause0 of 840 of 75159NCT04222088Trial comparisons
Artemether-lumefantrine (Coartem™) + Primaquine vs Chloroquine + Primaquine: serious adverse events0 of 840 of 75159NCT04222088Trial comparisons
ArTiMist vs Quinine: serious adverse events4 of 7710 of 74151NCT01258049Trial comparisons
Artemether-lumefantrine (Coartem™) + Primaquine vs Chloroquine + Primaquine: Adequate Clinical and Parasitological Response (ACPR)74 of 7572 of 74149NCT04222088Trial comparisons
Artemether-lumefantrine (Coartem™) + Primaquine vs Chloroquine + Primaquine: Early Treatment Failure (ETF)0 of 750 of 74149NCT04222088Trial comparisons
Artemether-lumefantrine (Coartem™) + Primaquine vs Chloroquine + Primaquine: Late Clinical Failure (LCF)1 of 750 of 74149NCT04222088Trial comparisons
Artemether-lumefantrine (Coartem™) + Primaquine vs Chloroquine + Primaquine: Late Parasitological Failure (LPF)0 of 752 of 74149NCT04222088Trial comparisons
ArTiMist vs Quinine: Late Parasitological Failure12 of 7014 of 71141NCT01258049Trial comparisons
ArTiMist vs Quinine: Number of Participants With Treatment Emergent Adverse Events and Serious Adverse Events, of Possible, Probably and Definite Causalities5 of 706 of 71141NCT01258049Trial comparisons
ArTiMist vs Quinine: Number of Deaths or Neurological Sequelae at Day 280 of 700 of 71141NCT01258049Trial comparisons
ArTiMist vs Quinine: Late Clinical Failure3 of 701 of 71141NCT01258049Trial comparisons
ArTiMist vs Quinine: Early Treatment Failure0 of 7014 of 71141NCT01258049Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0005920/comparisons