Disease · MONDO_0005921
Trials55
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.
1 to 20 of 55
Download this page as JSON| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01376167 | Ph 2B/3 Tafenoquine (TFQ) Study in Prevention of Vivax Relapse | Phase 2 | 851 | 2018-04-23 | Malaria, Vivax | CHLOROQUINE, PRIMAQUINE, TAFENOQUINE | Its record names the disease | ClinicalTrials.gov |
| NCT00440999 | Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria | Phase 3 | 456 | 2021-09-20 | Malaria | ARTESUNATE, CHLOROQUINE, PYRONARIDINE | Its record names the disease | ClinicalTrials.gov |
| NCT03610399 | Efficacy of 3 Regimens of Chloroquine and Primaquine for Treatment of P. Vivax Malaria, Cruzeiro do Sul, Acre, Brazil | Not applicable | 257 | 2021-08-09 | P Vivax, Malaria, Vivax | CHLOROQUINE, PRIMAQUINE | Its record names the disease | ClinicalTrials.gov |
| NCT02216123 | Study to Assess the Incidence of Hemolysis, Safety, and Efficacy of Tafenoquine (SB-252263, WR238605) Versus Primaquine in Subjects With Plasmodium Vivax Malaria | Phase 3 | 251 | 2018-05-16 | Malaria, Vivax | PRIMAQUINE, TAFENOQUINE | Its record names the disease | ClinicalTrials.gov |
| NCT04222088 | TES of Artemether-lumefantrine for Pf and Chloroquine for Pv in the Philippines From 2013-2014 | 159 | 2023-02-23 | Malaria, Falciparum Malaria, Vivax Malaria, Malaria Recrudescence | ARTEMETHER, CHLOROQUINE, LUMEFANTRINE, LUMEFANTRINE CO-ARTEMETHER, PRIMAQUINE | Its record names the disease | ClinicalTrials.gov | |
| NCT02802501 | Efficacy and Safety Study of Tafenoquine (TQ) Co-administered With Dihydroartemisinin-piperaquine (DHA-PQP) for the Radical Cure of Plasmodium Vivax (P. Vivax) Malaria | Phase 3 | 150 | 2020-07-24 | Malaria, Vivax | ARTENIMOL, PIPERAQUINE, PRIMAQUINE, TAFENOQUINE | Its record names the disease | ClinicalTrials.gov |
| NCT01290601 | Study to Evaluate the Efficacy and Safety of Tafenoquine for the Treatment of Plasmodium Vivax in Adults | Phase 2 | 70 | 2018-01-25 | Malaria, Plasmodium Vivax | CHLOROQUINE, PRIMAQUINE, TAFENOQUINE | Its record names the disease | ClinicalTrials.gov |
| NCT02563496 | A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) Malaria | Phase 2 | 60 | 2020-11-02 | Malaria, Vivax | TAFENOQUINE | Its record names the disease | ClinicalTrials.gov |
| NCT01753323 | Efficacy, Safety, Tolerability and Pharmacokinetics of KAF156 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infection | Phase 2 | 43 | 2015-08-19 | Malaria | GANAPLACIDE | Its record names the disease | ClinicalTrials.gov |
| NCT04368910 | Safety and Efficacy of Pyronaridine Artesunate Vs Chloroquine in Children and Adult Patients With Acute Vivax Malaria | Phase 3 | 30 | 2022-01-26 | Malaria | ARTESUNATE, CHLOROQUINE, PYRONARIDINE | Its record names the disease | ClinicalTrials.gov |
| NCT02573857 | A Study to Characterise the Antimalarial and Transmission Blocking Activity of a Single Dose of DSM265 or OZ439 in Healthy Subjects With Induced Blood Stage Plasmodium Falciparum or Plasmodium Vivax Infection | Phase 1/2 | 16 | 2020-06-05 | Malaria | ARTEFENOMEL, DSM-265 | Its record names the disease | ClinicalTrials.gov |
| NCT02880241 | MMV390048 POC in Patients With P. Vivax and P. Falciparum Malaria | Phase 2 | 8 | 2021-12-09 | Malaria | MMV-048 | Its record names the disease | ClinicalTrials.gov |
| NCT05096702 | Operational Feasibility of Appropriate Radical Cure of Plasmodium Vivax With Tafenoquine or Primaquine After Quantitative G6PD Testing in Brazil | 16,000 | Malaria, Vivax, G6PD Deficiency | PRIMAQUINE, TAFENOQUINE | Its record names the disease | ClinicalTrials.gov | ||
| NCT05879224 | Short Course Primaquine for the Radical Cure of P. Vivax Malaria - Indonesia | Not applicable | 2,999 | Vivax Malaria, G6PD Deficiency | PRIMAQUINE | Its record names the disease | ClinicalTrials.gov | |
| NCT01814683 | IMPROV (Improving the Radical Cure of Vivax Malaria) | Not applicable | 2,388 | Uncomplicated Vivax Malaria | PRIMAQUINE | Its record names the disease | ClinicalTrials.gov | |
| NCT06575647 | Vivax Elimination With Tafenoquine (VET) Study | Phase 4 | 1,242 | Malaria, Malaria, Vivax, Plasmodium Vivax, Plasmodium Vivax Malaria | TAFENOQUINE | Its record names the disease | ClinicalTrials.gov | |
| NCT06148792 | A Revised Tafenoquine Dose to Improve Radical Cure for Vivax Malaria | Phase 3 | 1,090 | Vivax Malaria | PRIMAQUINE, TAFENOQUINE | Its record names the disease | ClinicalTrials.gov | |
| NCT00682578 | A Comparative Study of Artekin With Standard Malarial Treatment Regimes in Afghanistan | Phase 3 | 1,086 | Uncomplicated Falciparum Malaria, Vivax Malaria | ARTENIMOL, ARTESUNATE, PIPERAQUINE, PYRIMETHAMINE, SULFADOXINE | Its record names the disease | ClinicalTrials.gov | |
| NCT07468526 | An Ultra-short Course of Primaquine for the Radical Cure of Vivax Malaria | Phase 3 | 1,019 | Malaria | PRIMAQUINE | Its record names the disease | ClinicalTrials.gov | |
| NCT04411836 | Effectiveness of Novel Approaches to Radical Cure With Tafenoquine and Primaquine | Phase 3 | 960 | Vivax Malaria, Plasmodium Vivax, Malaria, Vivax, Malaria Relapse | PRIMAQUINE, TAFENOQUINE | Its record names the disease | ClinicalTrials.gov |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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