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Disease · MONDO_0006502

Comparisons in its trials92

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Early Neuromuscular Blockade (NMB) vs Control: No Routine Early NMB: deaths from any cause213 of 501216 of 5051,006NCT02509078Trial comparisons
Early Neuromuscular Blockade (NMB) vs Control: No Routine Early NMB: serious adverse events28 of 50121 of 5051,006NCT02509078Trial comparisons
Rosuvastatin vs Placebo: serious adverse events34 of 37932 of 366745NCT00979121Trial comparisons
Vadadustat vs Placebo: deaths from any cause19 of 22119 of 227448NCT04478071Trial comparisons
Vadadustat vs Placebo: serious adverse events61 of 22173 of 227448NCT04478071Trial comparisons
Vadadustat vs Placebo: Number of Participants Who Are Classified 8 (Dead), 7 (Hospitalized, on Invasive Mechanical Ventilation or ECMO), or 6 (Hospitalized, on Non-invasive Ventilation or High Flow Oxygen Devices) on the NIAID Ordinal Scale
43 of 21653 of 223439NCT04478071Trial comparisons
Vadadustat vs Placebo: Number of Participants With a Total Score of 0 on the Modified Sequential Organ Failure Assessment (MSOFA) Scale156 of 214157 of 223437NCT04478071Trial comparisons
Brensocatib vs Placebo: Cumulative Incidence of Serious Adverse Events (SAEs)40 of 19235 of 214406NCT04817332Trial comparisons
Brensocatib vs Placebo: Discontinuation or Temporary Suspension of Treatment13 of 19212 of 214406NCT04817332Trial comparisons
Brensocatib vs Placebo: deaths from any cause29 of 19223 of 214406NCT04817332Trial comparisons
Brensocatib vs Placebo: serious adverse events40 of 19235 of 214406NCT04817332Trial comparisons
Brensocatib vs Placebo: Improvement of One Category From Admission Using 7-point Ordinal Scale.159 of 190186 of 214404NCT04817332Trial comparisons
Brensocatib vs Placebo: Number of Participants Discharged or to a National Early Warning Score (NEWS) of Equal or Less Than 2 and Maintained for 24 Hours, Whichever Occurs First.172 of 190195 of 214404NCT04817332Trial comparisons
Brensocatib vs Placebo: 28-day Mortality29 of 19023 of 214404NCT04817332Trial comparisons
FP-1201-lyo 10 μg vs Placebo: Exploratory, Extended Long-term Follow-up: Overall Mortality at Day 36051 of 14453 of 152296NCT02622724Trial comparisons
FP-1201-lyo 10 μg vs Placebo: Efficacy Endpoint: Mortality in Hospital1 of 1440 of 152296NCT02622724Trial comparisons
FP-1201-lyo 10 μg vs Placebo: deaths from any cause51 of 14453 of 152296NCT02622724Trial comparisons
FP-1201-lyo 10 μg vs Placebo: serious adverse events77 of 14477 of 152296NCT02622724Trial comparisons
Albuterol Sulfate vs Placebo: serious adverse events1 of 1521 of 130282NCT00434993Trial comparisons
Early Neuromuscular Blockade (NMB) vs Control: No Routine Early NMB: PTSS-14: Post-traumatic Stress-like Symptoms Scores >/= 4538 of 14531 of 122267NCT02509078Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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