Disease · MONDO_0006733
Comparisons in its trials67
Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.
1 to 20 of 67
Download this page as JSON| Comparison | Group 1, with the outcome | Group 2, with the outcome | Participants | Trial | Source |
|---|---|---|---|---|---|
| Reproxalap vs Vehicle: TE-SAEs of the Retina | 0 of 503 | 0 of 251 | 754 | NCT04735393 | Trial comparisons |
| Reproxalap vs Vehicle: TE-SAEs of Increase in Intraocular Pressure | 0 of 503 | 0 of 251 | 754 | NCT04735393 | Trial comparisons |
| Reproxalap vs Vehicle: Treatment-Emergent Serious Adverse Events (TE-SAEs) of Visual Acuity Decrease | 0 of 503 | 0 of 251 | 754 | NCT04735393 | Trial comparisons |
| Reproxalap vs Vehicle: TE-SAEs of the Cornea | 0 of 503 | 0 of 251 | 754 | NCT04735393 | Trial comparisons |
| OTX-101 0.09% vs Vehicle: deaths from any cause | 1 of 372 | 0 of 372 | 744 | NCT02688556 | Trial comparisons |
| OTX-101 0.09% vs Vehicle: serious adverse events | 6 of 372 | 2 of 372 | 744 | NCT02688556 | Trial comparisons |
| Lifitegrast vs Placebo: serious adverse events | 3 of 359 | 4 of 359 | 718 | NCT01743729 | Trial comparisons |
| Lifitegrast vs Placebo: serious adverse events | 4 of 357 | 4 of 354 | 711 | NCT02284516 | Trial comparisons |
| NOV03 vs Saline Solution: deaths from any cause | 0 of 311 | 0 of 309 | 620 | NCT04567329 | Trial comparisons |
| NOV03 vs Saline Solution: serious adverse events | 0 of 311 | 0 of 309 | 620 | NCT04567329 | Trial comparisons |
| RGN-259 vs Placebo: deaths from any cause | 0 of 299 | 0 of 302 | 601 | NCT02974907 | Trial comparisons |
| RGN-259 vs Placebo: serious adverse events | 3 of 299 | 2 of 302 | 601 | NCT02974907 | Trial comparisons |
| Lifitegrast 5.0% vs Placebo: serious adverse events | 5 of 293 | 2 of 295 | 588 | NCT01421498 | Trial comparisons |
| Carboxymethylcellulose Based Eye Drop Formulation A vs OPTIVE™: serious adverse events | 5 of 224 | 4 of 236 | 460 | NCT01664949 | Trial comparisons |
| Reproxalap vs Vehicle: TE-SAEs of the Retina | 0 of 299 | 0 of 148 | 447 | NCT04735393 | Trial comparisons |
| Reproxalap vs Vehicle: TE-SAEs of Visual Acuity Decrease | 0 of 299 | 0 of 148 | 447 | NCT04735393 | Trial comparisons |
| Reproxalap vs Vehicle: TE-SAEs of Increase in Intraocular Pressure | 0 of 299 | 0 of 148 | 447 | NCT04735393 | Trial comparisons |
| Reproxalap vs Vehicle: TE-SAEs of the Cornea | 0 of 299 | 0 of 148 | 447 | NCT04735393 | Trial comparisons |
| Lifitegrast vs Placebo: serious adverse events | 9 of 220 | 6 of 111 | 331 | NCT01636206 | Trial comparisons |
| CyclASol Ophthalmic Solution vs Vehicle Ophthalmic Solution: deaths from any cause | 0 of 162 | 0 of 166 | 328 | NCT03292809 | Trial comparisons |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/diseases/v1/MONDO_0006733/comparisons