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Disease · MONDO_0006781

Comparisons in its trials50

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Test Group vs Control Group: Safety by Assessment of the Number of Participants With Adverse Events (AEs)131 of 351184 of 346697NCT05857163Trial comparisons
Test Group vs Control Group: Eradication Rate of H.Pylori Infection323 of 351304 of 346697NCT05857163Trial comparisons
Test Group vs Control Group: deaths from any cause0 of 3510 of 346697NCT05857163Trial comparisons
Test Group vs Control Group: serious adverse events2 of 3512 of 346697NCT05857163Trial comparisons
TAK-438 20 mg vs Lansoprazole 30 mg: deaths from any cause0 of 2630 of 268531NCT03050359Trial comparisons
TAK-438 20 mg vs Lansoprazole 30 mg: serious adverse events1 of 2633 of 268531NCT03050359Trial comparisons
Vonoprazan 20 mg vs Esomeprazole 20 mg: deaths from any cause0 of 2560 of 254510NCT04198363Trial comparisons
Vonoprazan 20 mg vs Esomeprazole 20 mg: serious adverse events3 of 2565 of 254510NCT04198363Trial comparisons
RHB-105 vs Active Comparator: Number of Participants With Eradication of H. Pylori191 of 228131 of 227455NCT03198507Trial comparisons
RHB-105 vs Active Comparator: deaths from any cause0 of 2280 of 227455NCT03198507Trial comparisons
RHB-105 vs Active Comparator: serious adverse events1 of 2281 of 227455NCT03198507Trial comparisons
Reverse Hybrid Therapy vs Standard Triple Therapy: Number of Participants in Which H. Pylori Was Eradicated206 of 220191 of 220440NCT02359435Trial comparisons
Reverse Hybrid Therapy vs Standard Triple Therapy: serious adverse events0 of 2200 of 220440NCT02359435Trial comparisons
Quadruple Therapy (OBMT) 10 Days vs Triple Therapy (OAC) 7 Days: Number of Patients Experiencing Treatment Emergent Adverse Events.101 of 216112 of 222438NCT00669955Trial comparisons
Quadruple Therapy (OBMT) 10 Days vs Triple Therapy (OAC) 7 Days: serious adverse events4 of 2163 of 222438NCT00669955Trial comparisons
RHB-105 vs Active Comparator: Number of Participants With Eradication of H. Pylori in the Pharmacokinetic Population (PKP)187 of 207119 of 184391NCT03198507Trial comparisons
Sequential Therapy vs Modified Bismuth Quadruple Therapy: Counts of Participants With Adverse Event93 of 19572 of 195390NCT02159976Trial comparisons
Sequential Therapy vs Modified Bismuth Quadruple Therapy: Counts of Participants With Successful H. Pylori Eradication146 of 195134 of 195390NCT02159976Trial comparisons
Sequential Therapy vs Modified Bismuth Quadruple Therapy: serious adverse events0 of 1950 of 195390NCT02159976Trial comparisons
Sequential Therapy vs Modified Bismuth Quadruple Therapy: Counts of Participants Whose Drug Compliance is More Than 85%165 of 176170 of 177353NCT02159976Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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