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Disease · MONDO_0007039

Trials12

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT00863122Concentration and Activity of Lapatinib in Vestibular SchwannomasEarly phase 1262018-11-26Vestibular Schwannoma, NF2, Neurofibromatosis 2, Acoustic Neuroma, Auditory TumorLAPATINIBIts record names the diseaseClinicalTrials.gov
NCT01767792Phase 2 Study of Bevacizumab in Children and Young Adults With NF 2 and Progressive Vestibular SchwannomasPhase 2222020-05-27Neurofibromatosis Type 2, Progressive Vestibular SchwannomasBEVACIZUMABIts record names the diseaseClinicalTrials.gov
NCT00973739Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related TumorsPhase 2212016-03-22Neurofibromatosis 2, Vestibular SchwannomaLAPATINIBIts record names the diseaseClinicalTrials.gov
NCT02129647Study of Axitinib in Patients With Neurofibromatosis Type 2 and Progressive Vestibular SchwannomasPhase 2132021-12-01Neurofibromatosis Type 2, Vestibular SchwannomasAXITINIBIts record names the diseaseClinicalTrials.gov
NCT04283669Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular SchwannomasPhase 2122026-03-13Neurofibromatosis 2, Progressive Vestibular Schwannoma (VS)CRIZOTINIBIts record names the diseaseClinicalTrials.gov
NCT01419639Phase II Study of Everolimus (RAD001) in Children and Adults With Neurofibromatosis Type 2Phase 2102015-08-07Neurofibromatosis Type IIEVEROLIMUSIts record names the diseaseClinicalTrials.gov
NCT06553365Phase II Study of FCN-159 in NF2 Nerve Sheath TumorsPhase 230Nerve Sheath TumorLUVOMETINIBIts record names the diseaseClinicalTrials.gov
NCT02104323Endostatin Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related TumorsPhase 220Vestibular Schwannoma, Neurofibromatosis Type 2ENDOSTATINIts record names the diseaseClinicalTrials.gov
NCT00911248PTC299 for Treatment of Neurofibromatosis Type 2Phase 211Neurofibromatosis 2EMVODODSTATIts record names the diseaseClinicalTrials.gov
NCT01490476Efficacy and Safety Study of RAD001 in the Growth of the Vestibular Schwannoma(s) in Neurofibromatosis 2 (NF2) PatientsPhase 210Neurofibromatosis 2EVEROLIMUSIts record names the diseaseClinicalTrials.gov
NCT02934256Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related TumorsPhase 210Vestibular Schwannoma, Neurofibromatosis Type 2ICOTINIBIts record names the diseaseClinicalTrials.gov
NCT01345136Study of RAD001 for Treatment of NF2-related Vestibular SchwannomaPhase 24Neurofibromatosis Type 2, Neuroma, AcousticEVEROLIMUSIts record names the diseaseClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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