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Disease · MONDO_0009691

Comparisons in its trials17

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
PG -Mechlorethamine-MCH (Nitrogen Mustard) 0.02% PG Gel vs AP- Mechlorethamine-MCH (NM) 0.02% Compounded in Aquaphor: serious adverse events0 of 1280 of 127255NCT00168064Trial comparisons
Bexarotene Exposed vs Bexarotene Naive: deaths from any cause3 of 793 of 60139NCT00425555Trial comparisons
Bexarotene Exposed vs Bexarotene Naive: serious adverse events33 of 7923 of 60139NCT00425555Trial comparisons
Brentuximab Vedotin vs Methotrexate or Bexarotene: deaths from any cause22 of 6625 of 62128NCT01578499Trial comparisons
Brentuximab Vedotin vs Methotrexate or Bexarotene: serious adverse events18 of 6618 of 62128NCT01578499Trial comparisons
TSEBT Only vs TSEBT & Vorinostat: serious adverse events1 of 140 of 1428NCT01187446Trial comparisons
Group I (Pembrolizumab, Interferon Gamma-1b) vs Group II (Pembrolizumab, Interferon Gamma-1b): Overall Response Rate (ORR)6 of 160 of 1228NCT03063632Trial comparisons
Group I (Pembrolizumab, Interferon Gamma-1b) vs Group II (Pembrolizumab, Interferon Gamma-1b): Incidence of Adverse Events15 of 1612 of 1228NCT03063632Trial comparisons
Group I (Pembrolizumab, Interferon Gamma-1b) vs Group II (Pembrolizumab, Interferon Gamma-1b): deaths from any cause4 of 166 of 1228NCT03063632Trial comparisons
Group I (Pembrolizumab, Interferon Gamma-1b) vs Group II (Pembrolizumab, Interferon Gamma-1b): serious adverse events4 of 165 of 1228NCT03063632Trial comparisons
TSEBT Only vs TSEBT Plus Vorinostat: Complete Clinical Response (CCR)3 of 143 of 1327NCT01187446Trial comparisons
HyBryte (0.25 % Hypericin) vs Valchlor (Mechlorethamine): Number of Participants With a Treatment Response in the Modified Composite Assessment of Index Lesion Disease Severity (mCAILS) Score3 of 51 of 510NCT06149247Trial comparisons
HyBryte (0.25 % Hypericin) vs Valchlor (Mechlorethamine): deaths from any cause0 of 50 of 510NCT06149247Trial comparisons
HyBryte (0.25 % Hypericin) vs Valchlor (Mechlorethamine): serious adverse events0 of 50 of 510NCT06149247Trial comparisons
Dose Level 1 (Interleukin-15 2mcg/kg/Day) vs Dose Level 2 (Interleukin-15 4mcg/kg/Day): Number of Participants With Serious and Non-serious Adverse Events Assessed by the Common Terminology Criteria for Adverse Events (CTCAE v5.0)
3 of 33 of 36NCT04185220Trial comparisons
Dose Level 1 (Interleukin-15 2mcg/kg/Day) vs Dose Level 2 (Interleukin-15 4mcg/kg/Day): deaths from any cause2 of 31 of 36NCT04185220Trial comparisons
Dose Level 1 (Interleukin-15 2mcg/kg/Day) vs Dose Level 2 (Interleukin-15 4mcg/kg/Day): serious adverse events3 of 32 of 36NCT04185220Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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