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Disease · MONDO_0009807

Comparisons in its trials20

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Osteosarcoma vs Ewing Sarcoma: Incidence of Adverse Events45 of 4545 of 4590NCT02243605Trial comparisons
Osteosarcoma vs Ewing Sarcoma: deaths from any cause42 of 4537 of 4590NCT02243605Trial comparisons
Osteosarcoma vs Ewing Sarcoma: serious adverse events30 of 4531 of 4590NCT02243605Trial comparisons
Cohort 1: Measurable vs Cohort 2: Resection: deaths from any cause13 of 1520 of 3853NCT02470091Trial comparisons
Cohort 1: Measurable vs Cohort 2: Resection: serious adverse events6 of 154 of 3853NCT02470091Trial comparisons
Group 1 (Unilateral Recurrence) vs Group 2 (Bilateral Recurrence): serious adverse events4 of 270 of 1643NCT00066365Trial comparisons
A: Localized Resectable Disease vs C: Metastatic Tumors: serious adverse events3 of 310 of 1142NCT00667342Trial comparisons
Cohort A: Liposarcoma Crossover vs Cohort B: Osteosarcoma Crossover: Response Rate (RR), Cohorts A and B, After Crossover.0 of 150 of 1126NCT02048371Trial comparisons
Cisplatin Liposomal 24 mg/m2 vs Cisplatin Liposomal 36 mg/m2: deaths from any cause0 of 70 of 1219NCT00102531Trial comparisons
Cisplatin Liposomal 24 mg/m2 vs Cisplatin Liposomal 36 mg/m2: serious adverse events1 of 72 of 1219NCT00102531Trial comparisons
Dose Level 1 vs Dose Level 2: Number of Patients With Clinically Significant 12-Lead Electrocardiogram (ECG) Abnormalities1 of 100 of 313NCT05093322Trial comparisons
Dose Level 1 vs Dose Level 2: Number of Patients With Clinically Significant Laboratory Abnormalities0 of 101 of 313NCT05093322Trial comparisons
Dose Level 1 vs Dose Level 2: Number of Patients With Clinically Significant Physical Examination Abnormalities6 of 101 of 313NCT05093322Trial comparisons
Dose Level 1 vs Dose Level 2: deaths from any cause6 of 102 of 313NCT05093322Trial comparisons
Dose Level 1 vs Dose Level 2: Number of Patients With Clinically Significant Vital Signs Abnormalities0 of 100 of 313NCT05093322Trial comparisons
Dose Level 1 vs Dose Level 2: serious adverse events7 of 101 of 313NCT05093322Trial comparisons
Part A: 20 mg/kg (Phase 1) vs Part A PK: 20 mg/kg (Expansion): Disease Control Rate (Part A)0 of 60 of 612NCT03320330Trial comparisons
Dose Level 1 vs Dose Level 2: Number of Patients With Dose-Limiting Toxicities (DLT)0 of 82 of 311NCT05093322Trial comparisons
Dose Escalation Part With Sirolimus (Si) Dose 4 mg vs Dose Escalation Part With Sirolimus (SI) Dose 6 mg: Dose Escalation Part : Antitumor Activity Observed With Sirolimus Combined With CP, MT and ZA, 1-year Progression-free Survival (PFS)
6 of 61 of 39NCT02517918Trial comparisons
Dose Escalation Part With Sirolimus (Si) Dose 4 mg vs Dose Escalation Part With Sirolimus (SI) Dose 6 mg: Dose Escalation Part : Antitumor Activity Observed With Sirolimus Combined With CP, MT and ZA, 1-year Overall Survival (OS)
3 of 60 of 39NCT02517918Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

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