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Disease · MONDO_0011122

Comparisons in its trials224

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Sema 2.4 mg vs Placebo: deaths from any cause1 of 1,3061 of 6551,961NCT03548935Trial comparisons
Sema 2.4 mg vs Placebo: serious adverse events128 of 1,30642 of 6551,961NCT03548935Trial comparisons
NB32/48 vs Placebo: serious adverse events21 of 9927 of 4921,484NCT00567255Trial comparisons
NB32 vs Placebo: serious adverse events22 of 5841 of 200784NCT00456521Trial comparisons
15 mg or MTD - Tirzepatide vs 2.4 mg or MTD - Semaglutide: deaths from any cause0 of 3740 of 376750NCT05822830Trial comparisons
15 mg or MTD - Tirzepatide vs 2.4 mg or MTD - Semaglutide: serious adverse events18 of 37413 of 376750NCT05822830Trial comparisons
Tirzepatide - MTD vs Placebo: Number of Participants With Time to All-Cause Death19 of 36415 of 367731NCT04847557Trial comparisons
Tirzepatide - MTD vs Placebo: Number of Participants With Time to First Occurrence of HF Events29 of 36452 of 367731NCT04847557Trial comparisons
Tirzepatide - MTD vs Placebo: deaths from any cause19 of 36415 of 367731NCT04847557Trial comparisons
Tirzepatide - MTD vs Placebo: serious adverse events96 of 36494 of 367731NCT04847557Trial comparisons
Semaglutide 2.4 mg vs Placebo: deaths from any cause0 of 4070 of 204611NCT03611582Trial comparisons
Semaglutide 2.4 mg vs Placebo: serious adverse events37 of 4076 of 204611NCT03611582Trial comparisons
Tirzepatide vs Placebo: deaths from any cause1 of 2871 of 292579NCT04657016Trial comparisons
Tirzepatide vs Placebo: serious adverse events17 of 28714 of 292579NCT04657016Trial comparisons
Semaglutide 2.4 mg vs Placebo: deaths from any cause3 of 2634 of 266529NCT04788511Trial comparisons
Semaglutide 2.4 mg vs Placebo: serious adverse events35 of 26371 of 266529NCT04788511Trial comparisons
NB32 vs Placebo: serious adverse events13 of 3338 of 169502NCT00474630Trial comparisons
Lira 3.0 mg vs Placebo: serious adverse events9 of 2125 of 210422NCT00781937Trial comparisons
Semaglutide 2.4 mg vs Placebo: deaths from any cause0 of 2690 of 135404NCT05064735Trial comparisons
Semaglutide 2.4 mg vs Placebo: serious adverse events27 of 26911 of 135404NCT05064735Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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