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Disease · MONDO_0011385

Comparisons in its trials12

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Treatment vs Placebo: deaths from any cause0 of 430 of 4083NCT04272606Trial comparisons
Treatment vs Placebo: serious adverse events0 of 432 of 4083NCT04272606Trial comparisons
Intradiscal rhGDF-5 (1.0mg) vs Intradiscal rhGDF-5 (2.0mg): Treatment Emergent Adverse Events- Relationship to Study Drug2 of 141 of 2640NCT01158924Trial comparisons
Intradiscal rhGDF-5 (1.0mg) vs Intradiscal rhGDF-5 (2.0mg): serious adverse events1 of 144 of 2640NCT01158924Trial comparisons
Intradiscal rhGDF-5 (1.0mg) vs Intradiscal rhGDF-5 (2.0mg): Neurological Assessment for Motor Function and Reflexes/Sensory0 of 132 of 2538NCT01158924Trial comparisons
Intradiscal rhGDF-5 (0.25mg) vs Intradiscal rhGDF-5 (1.0mg): Neurological Assessment for Motor Function and Reflexes/Sensory0 of 70 of 2532NCT00813813Trial comparisons
Intradiscal rhGDF-5 (0.25mg) vs Intradiscal rhGDF-5 (1.0mg): Treatment Emergent Adverse Events- Relationship to Study Drug2 of 71 of 2532NCT00813813Trial comparisons
Intradiscal rhGDF-5 (0.25mg) vs Intradiscal rhGDF-5 (1.0mg): serious adverse events2 of 72 of 2532NCT00813813Trial comparisons
Intradiscal rhGDF-5 vs Vehicle Control: Treatment Emergent Adverse Events- Relationship to Study Drug0 of 221 of 931NCT01182337Trial comparisons
Intradiscal rhGDF-5 1.0mg vs Vehicle Control: Treatment Emergent Adverse Events- Relationship to Study Drug0 of 220 of 931NCT01182337Trial comparisons
Intradiscal rhGDF-5 vs Vehicle Control: serious adverse events5 of 222 of 931NCT01182337Trial comparisons
Intradiscal rhGDF-5 1.0mg vs Vehicle Control: Neurological Assessment for Motor Function and Reflexes/Sensory0 of 210 of 526NCT01182337Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0011385/comparisons