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Disease · MONDO_0011962

Comparisons in its trials64

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Arm I (Doxorubicin, Cisplatin, Paclitaxel) vs Arm II (Paclitaxel, Carboplatin): deaths from any cause271 of 647280 of 6651,312NCT00063999Trial comparisons
Arm I (Doxorubicin, Cisplatin, Paclitaxel) vs Arm II (Paclitaxel, Carboplatin): serious adverse events217 of 647156 of 6651,312NCT00063999Trial comparisons
Lenvatinib + Pembrolizumab vs Paclitaxel + Carboplatin: Number of Participants Who Experienced a Serious Adverse Event (SAE)230 of 42084 of 411831NCT03884101Trial comparisons
Lenvatinib + Pembrolizumab vs Paclitaxel + Carboplatin: Number of Participants Who Discontinued Study Intervention Due to an AE203 of 42080 of 411831NCT03884101Trial comparisons
Lenvatinib + Pembrolizumab vs Paclitaxel + Carboplatin: Number of Participants Who Experienced an Adverse Event (AE)418 of 420405 of 411831NCT03884101Trial comparisons
Lenvatinib + Pembrolizumab vs Paclitaxel + Carboplatin: Number of Participants Who Experienced an Immune-Related Adverse Event (irAE)316 of 42056 of 411831NCT03884101Trial comparisons
Lenvatinib 20 mg + Pembrolizumab 200 mg vs Treatment of Physician's Choice(TPC):Doxorubicin or Paclitaxel: Number of Participants Who Discontinued Study Treatment Due to a TEAE in All-comer Participants
180 of 40649 of 388794NCT03517449Trial comparisons
Lenvatinib 20 mg + Pembrolizumab 200 mg vs Treatment of Physician's Choice(TPC):Doxorubicin or Paclitaxel: Number of Partricipants With Treatment-emergent Adverse Events (TEAEs), Serious Adverse Events (SAEs), and Immune-Related Adverse Events (irAEs)
237 of 406121 of 388794NCT03517449Trial comparisons
Lenvatinib 20 mg + Pembrolizumab 200 mg vs Treatment of Physician's Choice(TPC):Doxorubicin or Paclitaxel: Number of Participants Who Discontinued Study Treatment Due to a TEAE in pMMR Participants140 of 34242 of 325667NCT03517449Trial comparisons
Arm I (Pelvic Radiation Therapy) vs Arm II (Brachytherapy, Paclitaxel, Carboplatin): Number of Participants With Recurrence or Death Events at Primary Analysis44 of 30143 of 300601NCT00807768Trial comparisons
Arm I (Pelvic Radiation Therapy) vs Arm II (Brachytherapy, Paclitaxel, Carboplatin): Number of Participants With Death Events39 of 30137 of 300601NCT00807768Trial comparisons
Arm I (Pelvic Radiation Therapy) vs Arm II (Brachytherapy, Paclitaxel, Carboplatin): serious adverse events9 of 28332 of 290573NCT00807768Trial comparisons
Arm 1 vs Arm 2: serious adverse events10 of 26121 of 278539NCT00006011Trial comparisons
AEZS-108 / Zoptarelin Doxorubicin vs Doxorubicin/ Standard Chemotherapy: deaths from any cause196 of 252188 of 249501NCT01767155Trial comparisons
AEZS-108 / Zoptarelin Doxorubicin vs Doxorubicin/ Standard Chemotherapy: serious adverse events92 of 25275 of 249501NCT01767155Trial comparisons
Arm I (Paclitaxel, Carboplatin, Metformin Hydrochloride) vs Arm II (Paclitaxel, Carboplatin, Placebo): deaths from any cause95 of 23495 of 235469NCT02065687Trial comparisons
Arm I (Paclitaxel, Carboplatin, Metformin Hydrochloride) vs Arm II (Paclitaxel, Carboplatin, Placebo): serious adverse events46 of 23453 of 235469NCT02065687Trial comparisons
Arm I (Brachytherapy, Radiation Therapy) vs Arm II (Brachytherapy, Radiation Therapy, Cisplatin): Number of Participants That Experienced Death on Study18 of 7421 of 82156NCT00492778Trial comparisons
Arm I (Brachytherapy, Radiation Therapy) vs Arm II (Brachytherapy, Radiation Therapy, Cisplatin): Number of Participants With Disease Progression or Death.27 of 7435 of 82156NCT00492778Trial comparisons
Arm I (Brachytherapy, Radiation Therapy) vs Arm II (Brachytherapy, Radiation Therapy, Cisplatin): deaths from any cause18 of 7421 of 82156NCT00492778Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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