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Disease · MONDO_0016367

Trials62

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 6 more are not shown, since the checks do not confirm them.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT00106184Rituximab for the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)Phase 22002015-03-04Myositis, Dermatomyositis, Polymyositis, Juvenile DermatomyositisRITUXIMABIts record names the diseaseClinicalTrials.gov
NCT00979654A Study to Evaluate the Long-Term Safety of MEDI-545 in Adult Participants With Systemic Lupus Erythematosus or MyositisPhase 21182016-08-23Systemic Lupus ErythematosusSIFALIMUMABIts record names the diseaseClinicalTrials.gov
NCT02728752Study Evaluating Efficacy and Safety of Octagam 10% in Patients With Dermatomyositis (Idiopathic Inflammatory Myopathy)Phase 3952021-04-21DermatomyositisHUMAN IMMUNOGLOBULIN GIts record names the diseaseClinicalTrials.gov
NCT03181893A Study In Adults With Moderate To Severe DermatomyositisPhase 2752023-09-14DermatomyositisDAZUKIBARTIts record names the diseaseClinicalTrials.gov
NCT03981744A Study of Ustekinumab in Participants With Active Polymyositis and Dermatomyositis Who Have Not Adequately Responded to One or More Standard-of-care TreatmentsPhase 3512024-05-13Polymyositis, DermatomyositisUSTEKINUMABIts record names the diseaseClinicalTrials.gov
NCT04999020Ravulizumab Versus Placebo in Adult Participants With DermatomyositisPhase 2/3382024-12-06DermatomyositisRAVULIZUMABIts record names the diseaseClinicalTrials.gov
NCT02043548Tocilizumab in the Treatment of Refractory Polymyositis and DermatomyositisPhase 2362020-10-30Dermatomyositis, PolymyositisTOCILIZUMABIts record names the diseaseClinicalTrials.gov
NCT00651040Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With PM and DMPhase 3312016-05-12Polymyositis, DermatomyositisMETHOTREXATE, PREDNISONEIts record names the diseaseClinicalTrials.gov
NCT02612857Trial of IMO-8400 in Adult Patients With DermatomyositisPhase 2302019-10-10DermatomyositisBAZLITORANIts record names the diseaseClinicalTrials.gov
NCT00504348Investigation in Myositis-associated Pneumonitis of Prednisolone And Concomitant TacrolimusPhase 2/3252020-03-24Interstitial Pneumonitis, Polymyositis, DermatomyositisPREDNISOLONE, TACROLIMUSIts record names the diseaseClinicalTrials.gov
NCT04033926A Phase 2 Study of KZR-616 to Evaluate Safety and Efficacy in Patients With Active Polymyositis or DermatomyositisPhase 2252024-01-03Polymyositis, DermatomyositisZETOMIPZOMIBIts record names the diseaseClinicalTrials.gov
NCT05192200An Extension Study for Participants Who Have Completed the Treatment Period of a Qualifying Parent StudyPhase 2242025-02-06DermatomyositisDAZUKIBARTIts record names the diseaseClinicalTrials.gov
NCT02466243Safety, Tolerability, and Efficacy of JBT-101 in Subjects With DermatomyositisPhase 2222023-01-19DermatomyositisLENABASUMIts record names the diseaseClinicalTrials.gov
NCT01148810Efficacy and Tolerability of BAF312 in Patients With Polymyositis and DermatomyositisPhase 2182019-04-25Polymyositis, DermatomyositisSIPONIMODIts record names the diseaseClinicalTrials.gov
NCT04628936Open-label Extension to the Phase 2 Crossover Study (PRESIDIO) Evaluating KZR-616 in Patients With PM and DM.Phase 2182024-06-05Polymyositis, DermatomyositisZETOMIPZOMIBIts record names the diseaseClinicalTrials.gov
NCT02029274Safety and Efficacy of BAF312 in DermatomyositisPhase 2172019-01-15Active DermatomyositisSIPONIMODIts record names the diseaseClinicalTrials.gov
NCT02347891Belimumab in Idiopathic Inflammatory MyositisPhase 2/3172024-02-09MyositisBELIMUMABIts record names the diseaseClinicalTrials.gov
NCT00112385A Pilot Study of Etanercept in DermatomyositisPhase 1162011-06-21DermatomyositisETANERCEPTIts record names the diseaseClinicalTrials.gov
NCT03267277Sodium Thiosulfate for Treatment of Calcinosis Associated With Juvenile and Adult DermatomyositisPhase 2/3152024-02-26Dermatomyositis, Idiopathic Inflammatory MyopathiesSODIUM THIOSULFATEIts record names the diseaseClinicalTrials.gov
NCT01906372Acthar in Treatment of Refractory Dermatomyositis and PolymyositisPhase 2122017-08-02Dermatomyositis, PolymyositisCORTICOTROPINIts record names the diseaseClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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